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Korean J Hepatol > Volume 13(3); 2007 > Article
The Korean Journal of Hepatology 2007;13(3): 363-369.
doi: http://dx.doi.org/10.3350/kjhep.2007.13.3.363
Comparison of Recent IgG Anti-HAV Prevalence between Two Hospitals in Seoul and Gyeonggi area
Tae Yeob Kim , Joo Hyun Sohn , Sang Bong Ahn , Byoung Kwan Son , Hang Lak Lee , Chang Soo Eun , Yong Cheol Jeon , Dong Soo Han
Department of Internal Medicine, Hanyang University, Guri, Korea
Abstract

Background/Aims:
Recently, the incidence of acute hepatitis A has increased nationwide and is related to the low rate of IgG anti-HAV. This study compared the prevalence of IgG anti-HAV in two university hospitals located in a large city and in a small city including a rural region according to age, gender, and the year of diagnosis.
Methods:
IgG anti-HAV was measured in a total of 4299 patients, who visited Seoul or Guri Hanyang University Hospital between January 2002 and December 2006.
Results:
The positive rates of the antibody in Seoul and Guri hospitals were 52.7% vs 57.1% in under the age of 1, 40.7% vs 42.2% in age of 1 to 4, 31.8% vs 30.3% in age of 5 to 9, 24.8% vs 27.1% in age of 10 to 14, 11.6% vs 18.2% in age of 15 to 19, 23.0% vs 20.3% in age of 20 to 24, 40.5% vs 42.9% in age of 25 to 29, 67.5% vs 75.0% in age of 30 to 34, 86.5% vs 88.1% in age of 35 to 39, 95.3% vs 93.6% in age of 40 to 44, 97.0% vs 98.7% in age of 45 to 49, and 98.5% vs 98.6% in patients who were more than 50, respectively. The positive rates of the antibody were not significantly different between two sites according to each age group and gender.
Conclusions:
The results confirmed the low rates of IgG anti-HAV, particularly in the ages of 10-24 that match the age group of recently increased incidence of acute hepatitis A nationwide. Therefore, measurement of the antibody and vaccination should be considered in this age group. (Korean J Hepatol 2007;13:363-369)
KeyWords: Hepatitis A; IgG anti-HAV; Prevalence; Korea
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