Clinical and Molecular Hepatology (Clin Mol Hepatol, CMH)

Review

Criteria and prognostic models for patients with hepatocellular carcinoma undergoing liver transplantation

Meng Sha, Jun Wang, Jie Cao, Zhi-Hui Zou, Xiao-ye Qu, Zhi-feng Xi, Chuan Shen, Ying Tong, Jian-jun Zhang, Seogsong Jeong, Qiang Xia

Clin Mol Hepatol. 2025;31(Suppl):S285-S300. Published online August 19, 2024

DOI: https://doi.org/10.3350/cmh.2024.0323

View: 1458 Download: 162 Crossref: 1

Liquid biopsy in hepatocellular carcinoma: Challenges, advances, and clinical implications

Jaeho Park, Yi-Te Lee, Vatche G. Agopian, Jessica S Liu, Ekaterina K. Koltsova, Sungyong You, Yazhen Zhu, Hsian-Rong Tseng, Ju Dong Yang

Clin Mol Hepatol. 2025;31(Suppl):S255-S284. Published online November 28, 2024

DOI: https://doi.org/10.3350/cmh.2024.0541

View: 1371 Download: 169

Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment

Soo Young Hwang, Pojsakorn Danpanichkul, Vatche Agopian, Neil Mehta, Neehar D. Parikh, Ghassan K. Abou-Alfa, Amit G. Singal, Ju Dong Yang

Clin Mol Hepatol. 2025;31(Suppl):S228-S254. Published online December 26, 2024

DOI: https://doi.org/10.3350/cmh.2024.0824

View: 3369 Download: 618 Crossref: 2

Mechanisms of hepatocellular carcinoma and cirrhosis development in concurrent steatotic liver disease and chronic hepatitis B

Saisai Zhang, Lung-Yi Mak, Man-Fung Yuen, Wai-Kay Seto

Clin Mol Hepatol. 2025;31(Suppl):S182-S195. Published online November 21, 2024

DOI: https://doi.org/10.3350/cmh.2024.0837

View: 1390 Download: 143 Crossref: 1

Role of noninvasive tests in the prognostication of metabolic dysfunction-associated steatotic liver disease

Yue Wang, Sherlot Juan Song, Yichong Jiang, Jimmy Che-To Lai, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Terry Cheuk-Fung Yip

Clin Mol Hepatol. 2025;31(Suppl):S51-S75. Published online June 27, 2024

DOI: https://doi.org/10.3350/cmh.2024.0246

View: 5694 Download: 203 Crossref: 2

Reply to Correspondence

Reply to correspondence on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial”

Hiroaki Kanzaki, Yujin Hoshida

Clin Mol Hepatol. 2025;31(1):e121-e122. Published online October 11, 2024

DOI: https://doi.org/10.3350/cmh.2024.0886

View: 866 Download: 35

Reply to correspondence on “UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma”

Martina Mang Leng Lei, Terence Kin Wah Lee

Clin Mol Hepatol. 2025;31(1):e119-e120. Published online August 5, 2024

DOI: https://doi.org/10.3350/cmh.2024.0621

View: 821 Download: 32

Reply to correspondence on “Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using vibration-controlled transient elastography: Systematic review and meta-analysis”

Mirko Zoncapè, Emmanuel A. Tsochatzis

Clin Mol Hepatol. 2025;31(1):e117-e118. Published online November 11, 2024

DOI: https://doi.org/10.3350/cmh.2024.0994

View: 693 Download: 19

Reply to correspondence on “Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting”

Antonio Bertoletti, Anthony T Tan

Clin Mol Hepatol. 2025;31(1):e113-e116. Published online October 11, 2024

DOI: https://doi.org/10.3350/cmh.2024.0867

View: 926 Download: 31

Correspondence

Correspondence to letter to the editor on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial”

Sung Hwan Lee, Sun Young Yim, Ji Hoon Kim, Sunyoung S Lee, Ahmed O Kaseb, Peng Wei, Ju-Seog Lee

Clin Mol Hepatol. 2025;31(1):e110-e112. Published online October 2, 2024

DOI: https://doi.org/10.3350/cmh.2024.0828

View: 885 Download: 47

Correspondence to letter to the editor on “Non-linear association between liver fibrosis scores and viral load in patients with chronic hepatitis B”

Gi-Ae Kim, Seung Won Choi, Young-Suk Lim

Clin Mol Hepatol. 2025;31(1):e108-e109. Published online August 5, 2024

DOI: https://doi.org/10.3350/cmh.2024.0619

View: 907 Download: 31

Correspondence to letter to the editor 2 on “Conventional and machine learning-based risk scores for patients with early-stage hepatocellular carcinoma”

Chun-Ting Ho, Elise Chia-Hui Tan, Chien-Wei Su

Clin Mol Hepatol. 2025;31(1):e101-e102. Published online November 6, 2024

DOI: https://doi.org/10.3350/cmh.2024.0946

View: 590 Download: 12

Correspondence to letter to the editor on “Sorafenib vs. lenvatinib in advanced hepatocellular carcinoma after atezolizumab/bevacizumab failure: a real-world study”

Young Eun Chon, Dong Yun Kim, Hong Jae Chon, Do Young Kim

Clin Mol Hepatol. 2025;31(1):e98-e100. Published online October 21, 2024

DOI: https://doi.org/10.3350/cmh.2024.0916

View: 767 Download: 45

Correspondence to editorial on “Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma”

Yu-Hang Ye, Shao-Lai Zhou

Clin Mol Hepatol. 2025;31(1):e90-e92. Published online November 11, 2024

DOI: https://doi.org/10.3350/cmh.2024.0998

View: 670 Download: 17

Correspondence to editorial 1 on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: insights from the IMbrave150 Trial”

Sung Hwan Lee, Sun Young Yim, Ji Hoon Kim, Sunyoung S. Lee, Ahmed O. Kaseb, Ju-Seog Lee

Clin Mol Hepatol. 2025;31(1):e81-e83. Published online October 7, 2024

DOI: https://doi.org/10.3350/cmh.2024.0829

View: 852 Download: 33 Crossref: 1

Correspondence to editorial on “UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL”

Renyu Zhang, Ding Wei, Zhinan Chen, Huijie Bian

Clin Mol Hepatol. 2025;31(1):e58-e60. Published online July 29, 2024

DOI: https://doi.org/10.3350/cmh.2024.0590

View: 892 Download: 55 Crossref: 1

Correspondence to editorial on “Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using vibration-controlled transient elastography: Systematic review and meta-analysis”

Young-Joo Jin, Seung Up Kim

Clin Mol Hepatol. 2025;31(1):e55-e57. Published online October 7, 2024

DOI: https://doi.org/10.3350/cmh.2024.0846

View: 782 Download: 20 Crossref: 1

Correspondence to editorial on “Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting”

Shunda Du, Karin Wisskirchen, Ke Zhang, Ulrike Protzer

Clin Mol Hepatol. 2025;31(1):e44-e47. Published online October 21, 2024

DOI: https://doi.org/10.3350/cmh.2024.0781

View: 991 Download: 41 Crossref: 1

Letter to the Editor

Urgent need for education on hepatocellular carcinoma surveillance among high-risk population in China

Lei Cai, Chao Li, Li-Yang Sun, Yong-Kang Diao, Ming-Da Wang, Tian Yang

Clin Mol Hepatol. 2025;31(1):e39-e43. Published online October 23, 2024

DOI: https://doi.org/10.3350/cmh.2024.0813

View: 800 Download: 51 Crossref: 1

Comprehensive analysis of transcriptomic biomarkers for predicting response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma

Binghua Li, Jingyuan Wen, Zhu Xu, Peng Yan, Bing Han, Decai Yu

Clin Mol Hepatol. 2025;31(1):e31-e34. Published online September 20, 2024

DOI: https://doi.org/10.3350/cmh.2024.0628

View: 1066 Download: 106 Crossref: 2

Comment: Non-invasive prediction of post-sustained virological response hepatocellular carcinoma in hepatitis C virus

Xinpu Miao, Haidong Wu, Jinrong Xu, Wei Cheng

Clin Mol Hepatol. 2025;31(1):e23-e24. Published online November 26, 2024

DOI: https://doi.org/10.3350/cmh.2024.1035

View: 654 Download: 20

Development of risk scores for prognosis prediction among patients with early-stage hepatocellular carcinoma

Xiping Shen, Ji Wu

Clin Mol Hepatol. 2025;31(1):e17-e18. Published online October 11, 2024

DOI: https://doi.org/10.3350/cmh.2024.0794

View: 924 Download: 46 Crossref: 1

Letter to the editor on “Sorafenib vs. Lenvatinib in advanced hepatocellular carcinoma after atezolizumab/bevacizumab failure: A real-world study”

Meng-Che Wu, Hui-Chin Chang, Yi-Sheng Jhang, Shuo-Yan Gau

Clin Mol Hepatol. 2025;31(1):e13-e14. Published online September 2, 2024

DOI: https://doi.org/10.3350/cmh.2024.0682

View: 1112 Download: 101 Crossref: 1

Grading severity of microvascular invasion in hepatocellular carcinoma: More details, more significance

Xiu-Ping Zhang, Fei-Fan Wu, Tian-Chen Zhang, Zhen-Qi Li, Ming-Gen Hu, Rong Liu

Clin Mol Hepatol. 2025;31(1):e10-e12. Published online November 26, 2024

DOI: https://doi.org/10.3350/cmh.2024.0986

View: 1077 Download: 57

Editorial

Stroma-tology: Predicting recurrence in cholangiocarcinoma: Editorial on “Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma”

Sergi Marco, Chiara Braconi

Clin Mol Hepatol. 2025;31(1):323-326. Published online October 29, 2024

DOI: https://doi.org/10.3350/cmh.2024.0932

View: 704 Download: 34 Crossref: 1

Personalized approaches to the treatment of hepatocellular carcinoma using immune checkpoint inhibitors: Editorial on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial”

Naoshi Nishida

Clin Mol Hepatol. 2025;31(1):311-315. Published online September 3, 2024

DOI: https://doi.org/10.3350/cmh.2024.0739

View: 912 Download: 66 Web of Science: 1 Crossref: 3

Transcriptomic signature in advanced hepatocellular carcinoma tissue to predict combination immunotherapy response: Editorial on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial”

Hiroaki Kanzaki, Yujin Hoshida

Clin Mol Hepatol. 2025;31(1):308-310. Published online August 30, 2024

DOI: https://doi.org/10.3350/cmh.2024.0726

View: 971 Download: 72 Crossref: 1

Identification of KCTD17 as a Ras stabilizer in hepatocellular carcinoma: Editorial on “KCTD17-mediated Ras stabilization promotes hepatocellular carcinoma progression”

Rainbow Wing Hei Leung, Terence Kin Wah Lee

Clin Mol Hepatol. 2025;31(1):304-307. Published online August 30, 2024

DOI: https://doi.org/10.3350/cmh.2024.0718

View: 900 Download: 48 Crossref: 1

UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma: Editorial on “UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL”

Martina Mang Leng Lei, Terence Kin Wah Lee

Clin Mol Hepatol. 2025;31(1):281-285. Published online July 23, 2024

DOI: https://doi.org/10.3350/cmh.2024.0568

View: 1318 Download: 78 Crossref: 2

The use of transient elastography for predicting hepatocellular carcinoma in chronic hepatitis B patients: Editorial on “Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using vibration-controlled transient elastography: Systematic review and meta-analysis”

Mirko Zoncapè, Emmanuel A. Tsochatzis

Clin Mol Hepatol. 2025;31(1):268-274. Published online September 24, 2024

DOI: https://doi.org/10.3350/cmh.2024.0817

View: 925 Download: 46 Crossref: 2

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