Background/Aims Computed tomography (CT) hepatic volumetry is currently accepted as the most reliable method for preoperative estimation of graft weight in living donor liver transplantation (LDLT). However, several factors can cause inaccuracies in CT volumetry compared to real graft weight. The purpose of this study was to determine the frequency and degree of resection plane-dependent error in CT volumetry of the right hepatic lobe in LDLT.
Methods Forty-six living liver donors underwent CT before donor surgery and on postoperative day 7. Prospective CT volumetry (VP) was measured via the assumptive hepatectomy plane. Retrospective liver volume (VR) was measured using the actual plane by comparing preoperative and postoperative CT. Compared with intraoperatively measured weight (W), errors in percentage (%) VP and VR were evaluated. Plane-dependent error in VP was defined as the absolute difference between VP and VR. % plane-dependent error was defined as follows: |VP–VR|/W∙100.
Results Mean VP, VR, and W were 761.9 mL, 755.0 mL, and 696.9 g. Mean and % errors in VP were 73.3 mL and 10.7%. Mean error and % error in VR were 64.4 mL and 9.3%. Mean plane-dependent error in VP was 32.4 mL. Mean % plane-dependent error was 4.7%. Plane-dependent error in VP exceeded 10% of W in approximately 10% of the subjects in our study.
Conclusions There was approximately 5% plane-dependent error in liver VP on CT volumetry. Plane-dependent error in VP exceeded 10% of W in approximately 10% of LDLT donors in our study. This error should be considered, especially when CT volumetry is performed by a less experienced operator who is not well acquainted with the donor hepatectomy plane.
Citations
Citations to this article as recorded by
Radiomics Beyond Radiology: Literature Review on Prediction of Future Liver Remnant Volume and Function Before Hepatic Surgery Fabrizio Urraro, Giulia Pacella, Nicoletta Giordano, Salvatore Spiezia, Giovanni Balestrucci, Corrado Caiazzo, Claudio Russo, Salvatore Cappabianca, Gianluca Costa Journal of Clinical Medicine.2025; 14(15): 5326. CrossRef
The Effect of Portal Vein Variants on the Margin of Error in Graft Volume Calculation in Living Donor Right Lobe Liver Transplantation Feyza Sönmez Topcu, Veysel Ersan, Emrah Şahin, Adem Tunçer, Hasret Ayyıldız Civan, Abuzer Dirican, Bülent Ünal Transplantation Proceedings.2025; 57(9): 1773. CrossRef
Optimizing accuracy: a comparative analysis of preoperative liver volumetry in living donor liver transplantation from a surgeon’s perspective – a retrospective cohort study EunJin Choi, Seok-Hwan Kim International Journal of Surgery.2025; 111(11): 8149. CrossRef
3-D reconstruction in liver surgery: a systematic review Filippo Banchini, Patrizio Capelli, Anis Hasnaoui, Gerardo Palmieri, Andrea Romboli, Mario Giuffrida HPB.2024; 26(10): 1205. CrossRef
Fully automated assessment of the future liver remnant in a blood-free setting via CT before major hepatectomy via deep learning Tingting Xie, Jingyu Zhou, Xiaodong Zhang, Yaofeng Zhang, Xiaoying Wang, Yongbin Li, Guanxun Cheng Insights into Imaging.2024;[Epub] CrossRef
Accuracy of preoperative liver volumetry in living donor liver transplantation—A systematic review and meta-analysis Mika S. Buijk, Marcel Dijkshoorn, Roy S. Dwarkasing, Alicia C. Chorley, Robert C. Minnee, Markus U. Boehnert Journal of Liver Transplantation.2023; 10: 100150. CrossRef
Prediction of Posthepatectomy Liver Failure with a Combination of Albumin-Bilirubin Score and Liver Resection Percentage Kazuhiro Takahashi, Masahiko Gosho, Jaejeong Kim, Osamu Shimomura, Yoshihiro Miyazaki, Kinji Furuya, Yoshimasa Akashi, Tsuyoshi Enomoto, Shinji Hashimoto, Tatsuya Oda Journal of the American College of Surgeons.2022; 234(2): 155. CrossRef
CT and MR imaging evaluation of living liver donors Federica Vernuccio, Susan A. Whitney, Kadiyala Ravindra, Daniele Marin Abdominal Radiology.2021; 46(1): 17. CrossRef
Estimation of the Right Posterior Section Volume in Live Liver Donors: Semiautomated CT Volumetry Using Portal Vein Segmentation So Yeong Jeong, Jeongjin Lee, Kyoung Won Kim, Jin Kyoo Jang, Heon-Ju Kwon, Gi Won Song, Sung Gyu Lee Academic Radiology.2020; 27(2): 210. CrossRef
Reproducibility and reliability of computed tomography volumetry in estimation of the right‐lobe graft weight in adult‐to‐adult living donor liver transplantation: Cantlie’s line vs portal vein territorialization Heon‐Ju Kwon, Kyoung Won Kim, Jin Kyoo Jang, Jeongjin Lee, Gi‐Won Song, Sung‐Gyu Lee Journal of Hepato-Biliary-Pancreatic Sciences.2020; 27(8): 541. CrossRef
Liver Graft Volume Estimation by Manual Volumetry and Software-Aided Interactive Volumetry: Which is Better? Birkan Bozkurt, Ertan Emek, Turkmen Arikan, Ozgur Ceyhan, Pinar Yazici, Tolga Sahin, Elmar Mammadov, Ayfer Serin, Nagihan Inan Gurcan, Yildiray Yuzer, Yaman Tokat Transplantation Proceedings.2019; 51(7): 2387. CrossRef
Clinical implication of hepatic volumetry for living donor liver transplantation Woo Kyoung Jeong Clinical and Molecular Hepatology.2018; 24(1): 51. CrossRef
MRI in donor candidates for living donor liver transplant: Technical and practical considerations Bohyun Kim, So Yeon Kim, Kyoung Won Kim, Hye Young Jang, Jong Keon Jang, Gi Won Song, Sung Gyu Lee Journal of Magnetic Resonance Imaging.2018; 48(6): 1453. CrossRef
Background/Aims Clinical validation is required to determine whether Doppler measurements are comparable before and after administering ultrasound contrast agent (USCA). The purpose of this study is to explore whether the use of USCA affects spectral Doppler analysis in recipients of liver transplantation (LT).
Methods For this study, 36 patients were examined using Doppler ultrasonography (US) along with a contrast-enhanced US for surveillance of vascular complications after LT. The following spectral Doppler US parameters were measured before and after administration of USCA: peak systolic velocity, end-diastolic velocity, resistive index, and systolic acceleration time of the graft hepatic artery; peak flow velocity of the graft portal vein; and peak flow velocity and venous pulsatility index of the graft hepatic vein.
Results The mean peak systolic and end-diastolic velocities of the hepatic artery and the peak flow velocity of the portal and hepatic veins were increased after intravenously administration of the USCA, ranging from 10% to 13%. However, the changes were not statistically significant (P=0.097, 0.103, 0.128, and 0.190, respectively). There were no significant differences in other measured parameters, including the resistive index (P=0.205) and systolic acceleration time (P=0.489) of the hepatic artery and venous pulsatility index (P=0.494) of the hepatic vein.
Conclusions The measured velocities of graft hepatic vessels tended to increase after administration of USCA, but without statistical significance. The comparison of serial Doppler parameters with or without injection of USCA is valid during Doppler surveillance in recipients of LT.
Citations
Citations to this article as recorded by
Effect of contrast-enhanced ultrasound (CEUS) on liver stiffness measurements obtained by transient and shear-wave elastography Stefano KAYALI, Andrea PASTA, Rinaldo PELLICANO, Sharmila FAGOONEE, Elisabetta GIULIANA, Chiara FACCHINI, Simona PILI, Silvia BUCCILLI, Sara LABANCA, Paolo BORRO Panminerva Medica.2022;[Epub] CrossRef
First
Prev
