A 31-year-old male visited a local hospital due to sudden-onset severe abdominal pain. Abdominal computed tomography revealed a solid cystic mass with a size of approximately 12 cm and exhibiting both hemorrhage and fluid collection in the pelvic cavity. Emergency angiography and embolization were performed, and a large hepatic tumor was subsequently surgically resected. The tumor cells stained positive for human melanoma black-45 and smooth-muscle actin, and the pathologic diagnosis was hepatic angiomyolipoma. This case report also discusses the spontaneous rupture of a hepatic angiomyolipoma.
Citations
Citations to this article as recorded by
Abdominal Manifestations of Tuberous Sclerosis Complex Muhammad Nabeel Akram, Kai Xue, Kaustubh G. Shiralkar, Steven S. Chua Applied Radiology.2025; 54(2): 21. CrossRef
A Resected Case of Hepatic Angiomyolipoma with Tumor Hemorrhage and Undetectable Fat Causing Diagnostic Difficulty Yumeo Tateyama, Yuichi Yamazaki, Ayaka Katayama, Tatsuma Murakami, Hiroki Tojima, Kenichiro Araki, Takaaki Sano, Ken Shirabe, Toshio Uraoka Surgical Case Reports.2025; 11(1): n/a. CrossRef
Case of Hepatic Angiomyolipoma: An Unusual Hepatic Lesion with a Review of Diagnostic and Management Challenges Bushra Kurban, Deepti Shukla, Shamas Zaman, Muhannad Al Okla The Korean Journal of Gastroenterology.2025; 85(3): 404. CrossRef
Surgical management of liver angiomyolipoma: eighteen years of experience from a single-reference center Oğuzhan Şal, Beslen Göksoy, Anas Al Hajeh, Leman Damla Ercan, Melek Büyük, Kürşat Rahmi Serin HPB.2024; 26(1): 156. CrossRef
Hepatic Angiomyolipoma With Predominant Lipomatous Component: A Rare Entity Jaweria Pervaiz, Samina Zaman, Sohaib Khalid, Zubaria Rafique, Rida Noor Cureus.2024;[Epub] CrossRef
Hepatic perivascular epithelioid cell tumors: The importance of preoperative diagnosis Shuai Yan, Jia-Jie Lu, Lin Chen, Wei-Hua Cai, Jin-Zhu Wu World Journal of Gastroenterology.2024; 30(13): 1926. CrossRef
Minimally Invasive Image-Guided Procedures for Benign Liver Lesions Fiza M. Khan, Nariman Nezami, Florian Stumpf, Tyler A. Smith, Margarita Revizin, Adam Fang, Mohammad F. Loya, Rahul A. Sheth, Steven Yevich, Peiman Habibillahi Digestive Disease Interventions.2023; 07(03): 202. CrossRef
A rare case of giant hepatic angiomyolipoma with subcapsular rupture Cuiting Wu, Yang Yang, Feng Tian, Yuan Xu, Qiang Qu Frontiers in Surgery.2023;[Epub] CrossRef
Transcatheter arterial embolization followed by laparoscopic anatomic hepatectomy for spontaneous rupture of a giant hepatic angiomyolipoma: a case report Jianjun Wang, Ruizi Shi, Hua Luo, Pei Yang, Huiwen Luo, Ziqing Gao, Decai Wang, Xintao Zeng Frontiers in Surgery.2023;[Epub] CrossRef
Giant hepatic angiomyolipoma presenting with severe anemia: A surgical case report and review of literature Cong Long Nguyen, Ham Hoi Nguyen, Tuan Hiep Luong, Nghe Tinh Nguyen, Van Khang Le, Truong Khanh Vu International Journal of Surgery Case Reports.2022; 94: 107087. CrossRef
Retrospective analysis of hepatic perivascular epithelioid cell tumour (PEComa) in a single centre for clinical diagnosis and treatment clinical diagnosis and treatment of hepatic PEComa Xiao Yang, Qingyuan Wang, Xiao Zhou, Haoming Zhou, Wenbo Jia, Chunyang Hu, Jian Chu, Lianbao Kong Medicine.2022; 101(25): e29506. CrossRef
Clinical characteristics and outcomes of patients with hepatic angiomyolipoma: A literature review Paul Calame, Gaëlle Tyrode, Delphine Weil Verhoeven, Sophie Félix, Anne Julia Klompenhouwer, Vincent Di Martino, Eric Delabrousse, Thierry Thévenot World Journal of Gastroenterology.2021; 27(19): 2299. CrossRef
Laparoscopic hepatectomy for hepatic angiomyolipoma with preoperative diagnosis of other malignancy: a report of 2 cases Yoh Asahi, Toshiya Kamiyama, Tatsuya Orimo, Shingo Shimada, Akihisa Nagatsu, Yuzuru Sakamoto, Chihiro Ishizuka, Kazuya Hamada, Hirofumi Kamachi, Emi Takakuwa, Tomoko Mitsuhashi, Akinobu Taketomi Surgical Case Reports.2021;[Epub] CrossRef
Diagnosis and surgical treatment of a rare hepatic angiomyolipoma with internal hemorrhage Mizelle D'Silva, Hee Young Na, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon, Hae Won Lee, Jun Suh Lee, Boram Lee, Moonhwan Kim Annals of Hepato-Biliary-Pancreatic Surgery.2021; 25(4): 532. CrossRef
Hepatic angiomyolipoma: an international multicenter analysis on diagnosis, management and outcome Anne J. Klompenhouwer, Roy S. Dwarkasing, Michael Doukas, Silvia Pellegrino, Valerie Vilgrain, Valerie Paradis, Olivier Soubrane, Joal D. Beane, David A. Geller, Michael A. Nalesnik, Verena Tripke, Hauke Lang, Moritz Schmelzle, Johann Pratschke, Wenzel Sc HPB.2020; 22(4): 622. CrossRef
Imaging hepatic angiomyolipomas: key features and avoiding errors J. Seow, M. McGill, W. Wang, P. Smith, M. Goodwin Clinical Radiology.2020; 75(2): 88. CrossRef
Epithelioid angiomyolipoma (EAML) of liver is a rare neoplasm. Hepatic EAML is often misdiagnosed as other neoplasms such as hepatocellular carcinoma due to non-specific clinical and radiologic features. The morphologic features under microscope and immunohistochemistry staining profile are important in the diagnosis EAML. Here, we report a case of 52-year-old man who found 1.2 cm mass in liver by routine checkup. On the impression of hepatocellular carcinoma, lateral sectionectomy of the liver was done. Microscopically, the tumor is composed of predominant epithelioid cells with vascular component and foamy cells. These cells were positive for HMB45, MelanA, and smooth muscle actin and negative for epithelial membrane antigen. The final diagnosis was hepatic EAML.
Citations
Citations to this article as recorded by
Hepatic epithelioid angiomyolipoma treated with laparoscopic resection and transcatheter arterial embolization first time: A case report and review of literature Fei Wang, Zhong-Xing Shi, Xin-Yu He, Xue-Jing Han, Jia-Hui Wang, Jia-Yi Yang, Li-Ming Cui World Journal of Gastrointestinal Surgery.2026;[Epub] CrossRef
Epithelioid angiomyolipoma of the liver in a patient with Li-Fraumeni syndrome: a case report Yaewon Yang, Jisun Lee, Chang Gok Woo, Ok-Jun Lee, Seung-Myoung Son Diagnostic Pathology.2024;[Epub] CrossRef
The Difficulties of Diagnosis Giant Angiomyolipoma of the Liver: Clinical Case and Literature Review A. V. Arablinskii, O. P. Myasnyankina, A. A. Sedova, M. P. Onischenko Journal of oncology: diagnostic radiology and radiotherapy.2024; 7(1): 98. CrossRef
Hepatic epithelioid angiomyolipoma: magnetic resonance imaging characteristics Li Junhao, Zhang Hongxia, Guo Jiajun, Ikram Ahmad, Gao Shanshan, Li Jianke, Chen Lingli, Ji Yuan, Zeng Mengsu, Wang Mingliang Abdominal Radiology.2023;[Epub] CrossRef
Hepatic epithelioid angiomyolipoma is scattered and unsuitable for surgery: a case report Xiangreng Cai, Shuchuan Sun, Yuxin Deng, Jiangxin Liu, Siyuan Pan Journal of International Medical Research.2023;[Epub] CrossRef
Epithelioid hepatic angiomyolipoma in pregnancy: A case report Abdullah Khalid, Bilal Ahmed Khan, Zubair Saeed, Usman Atique, Muhammad Yasir Khan, Ihsan -ul-Haq International Journal of Surgery Case Reports.2023; 111: 108902. CrossRef
Hepatic angiomyolipoma Simone A. Günster, Mia Kim, Johan F. Lock, Katica Krajinovic International Journal of Surgery Case Reports.2020; 77(C): 345. CrossRef
Angiomiolipoma epitelioide/PEComa hepático e hiperplasia nodular focal en una paciente con antecedentes de melanoma cutáneo Isidro Machado, Ana Marhuenda, Marta Trallero, María Caballero, Jesús Santos, Julia Cruz, Rafael Estevan Revista Española de Patología.2019; 52(4): 250. CrossRef
Ultrasound‐guided fine needle aspiration cytology in the diagnosis of hepatic and pancreatic perivascular epithelioid cell tumors: A case series Valentina Sangiorgio, Lorenzo Daniele, Teresa Gallo, Rodolfo Rocca, Cristina Fava, Paola Campisi, Giovanni De Rosa Diagnostic Cytopathology.2019; 47(4): 315. CrossRef
Two case reports and literature review for hepatic epithelioid angiomyolipoma: Pitfall of misdiagnosis Jia-Xi Mao, Fei Teng, Cong Liu, Hang Yuan, Ke-Yan Sun, You Zou, Jia-Yong Dong, Jun-Song Ji, Jun-Feng Dong, Hong Fu, Guo-Shan Ding, Wen-Yuan Guo World Journal of Clinical Cases.2019; 7(8): 972. CrossRef
Hepatic epithelioid angiomyolipoma: contribution of a new case María Ángeles Valero González, Yolanda Núñez Delgado, Ana Milena Muñoz Revista Española de Enfermedades Digestivas.2019;[Epub] CrossRef
Imaging appearance of renal epithelioid angiomyolipoma Jianguo Zhu, Haige Li, Liucheng Ding, Hongyong Cheng Medicine.2018; 97(1): e9563. CrossRef
Hepatic Epithelioid Angiomyolipoma and 18F-FDG PET/CT Yiqiu Zhang, Beilei Li, Jun Hou, Haojun Yu, Hongcheng Shi Clinical Nuclear Medicine.2018; 43(6): 422. CrossRef
Liver Angiomyolipoma Mimicking Malignancy in Liver Jeong-Ju Yoo, Min Jung Jung, Sang Gyune Kim, Young Seok Kim Clinical Ultrasound.2018; 3(1): 15. CrossRef
Hepatic epithelioid angiomyolipoma with renal metastasis: radiologic-pathologic correlation Adrian Marcuzzi, Ehsan A. Haider, Ishaq S. Al Salmi Radiology Case Reports.2018; 13(4): 829. CrossRef
Comparison of MRI Features of Epithelioid Hepatic Angiomyolipoma and Hepatocellular Carcinoma: Imaging Data From Two Centers Weihai Liu, Jiawei Wang, Qiang Huang, Qinyan Lu, Wenjie Liang Frontiers in Oncology.2018;[Epub] CrossRef
Clinical features, natural history and outcomes of pseudolymphoma of liver: A case-series and systematic review Wei Jiang, Dongbo Wu, Qin Li, Chang-Hai Liu, Qingmin Zeng, Enqiang Chen, Changli Lu, Hong Tang Asian Journal of Surgery.2023; 46(2): 841. CrossRef
Liver Pseudolymphoma (Reactive Lymphoid Hyperplasia): Difficulty in
Radiological and Pathological Diagnosis Suleyman Bakdik, Necdet Poyraz, Teyfik Kucukkartallar, Pembe Oltulu Current Medical Imaging Formerly Current Medical Imaging Reviews.2022; 18(3): 357. CrossRef
Spontaneous Regression of Hepatocellular Carcinoma From Autoinfarction and Implications on Liver Transplantation Kevin Singh ACG Case Reports Journal.2022; 9(7): e00825. CrossRef
Hepatic Reactive Lymphoid Hyperplasia and Primary Hepatic Lymphoma: Ultrasound Features and Differentiation Diagnosis Qiao, MD Xiaohui, Chen, MD Kun, Chen, MD, PhD Gang, Xue, MD Liyun, Cheng, MD Guangwen, Ding, MD, PhD Hong ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY.2021; 5(2): 63. CrossRef
Bile duct adenoma: imaging features and radiologic–pathologic correlation Ryoji Tatsumi, Shin Ichihara, Hirokazu Suii, Masakatsu Yamaguchi, Tomohiro Arakawa, Tomoaki Nakajima, Yasuaki Kuwata, Itaru Ozeki, Shuhei Hige, Joji Toyota, Yoshiyasu Karino Japanese Journal of Radiology.2020; 38(6): 561. CrossRef
A case of reactive lymphoid hyperplasia of the liver in a patient with autoimmune hepatitis Hiroki Kanno, Hisamune Sakai, Toru Hisaka, Satoki Kojima, Ryuta Midorikawa, Shogo Fukutomi, Yoriko Nomura, Yuichi Goto, Toshihiro Sato, Munehiro Yoshitomi, Ryuichi Kawahara, Koji Okuda Surgical Case Reports.2020;[Epub] CrossRef
Reactive lymphoid hyperplasia of the liver Wenyan Zhang, Shusen Zheng Medicine.2019; 98(30): e16491. CrossRef
Hepatic pseudolymphoma: imaging features on dynamic contrast-enhanced MRI and diffusion-weighted imaging Yang Zhou, XiaoLin Wang, Chen Xu, GuoFeng Zhou, MengSu Zeng, PengJu Xu Abdominal Radiology.2018; 43(9): 2288. CrossRef
Magnetic resonance findings of hepatic epithelioid hemangioendothelioma: emphasis on hepatobiliary phase using Gd-EOB-DTPA Jeong Hyun Lee, Woo Kyoung Jeong, Young Kon Kim, Won Jae Lee, Sang Yun Ha, Kyoung Won Kim, Jihun Kim Abdominal Radiology.2017; 42(9): 2261. CrossRef
Pseudolymphoma (reactive lymphoid hyperplasia) of the liver: A clinical challenge Yong Kyong Kwon World Journal of Hepatology.2015; 7(26): 2696. CrossRef
OPTIMIZATION OF EXTRACTION CONDITION FOR ALISOL B AND ALISOL B ACETATE IN ALISMATIS RHIZOMA USING RESPONSE SURFACE METHODOLOGY A Yeong Lee, Jun Yeon Park, Jin Mi Chun, Byeong Cheol Moon, Byoung Kab Kang, Young Bae Seo, Hyeun-Kyoo Shin, Ho Kyoung Kim Journal of Liquid Chromatography & Related Technologies.2013; 36(4): 513. CrossRef
Hepatic Angiomyolipoma with Variable Histologic Features: 8 Cases Resembling Hepatocellular Carcinoma or Inflammatory Pseudotumor Ilseon Hwang, Eunsil Yu, Kyung-Ja Cho The Korean Journal of Gastroenterology.2012; 60(4): 242. CrossRef
First
Prev
