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"MAFLD"

Review

Incretin-based therapies for cardio-kidney-liver-metabolic disease: the role of the liver in the modern era of chronic disease management
Harendran Elangovan, Rohit Loomba, Mark Muthiah, Jörn Schattenberg, Ming Hua Zheng, Mazen Noureddin, Christos Mantzoros, Jacob George
Clin Mol Hepatol 2026;32(1):170-183.
Published online October 27, 2025
DOI: https://doi.org/10.3350/cmh.2025.0857
Steatotic liver disease (SLD) is a leading cause of disease globally and demands new therapeutic approaches to mitigate underlying metabolic dysregulation. Incretin-based therapies are emerging as a viable prospect to fulfil this unmet niche. A literature review to inform the evidence base for incretin focussed pharmacology in the metabolic liver diseases space and an informed commentary on unmet areas of need. Incretin-based therapeutics demonstrate multifarious benefits across the chronic metabolic disease spectrum with promising data across the continuum of pathology.
  • 1,132 View
  • 87 Download

Letter to the Editor

Steatotic liver disease

Citations

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  • Associations between systemic inflammatory biomarkers and metabolic dysfunction associated steatotic liver disease: a cross-sectional study of NHANES 2017–2020
    Xin Qiu, Shuang Shen, Nizhen Jiang, Yifei Feng, Guodong Yang, Donghong Lu
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Correspondence to letter to the editor 2 on “Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma: A nationwide cohort study”
    Seogsong Jeong, Won Kim, Sang Min Park
    Clinical and Molecular Hepatology.2025; 31(2): e210.     CrossRef
  • 7,560 View
  • 92 Download
  • 2 Web of Science
  • Crossref

Reviews

Steatotic liver disease

Precision medicine and nucleotide-based therapeutics to treat steatotic liver disease
Andrea Caddeo, Stefano Romeo
Clin Mol Hepatol 2025;31(Suppl):S76-S93.
Published online August 5, 2024
DOI: https://doi.org/10.3350/cmh.2024.0438
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a complex multifactorial disease and becoming the leading cause of liver-related morbidity and mortality. MASLD spans from isolated steatosis to metabolic dysfunction-associated steatohepatitis (MASH), that may progress to cirrhosis and hepatocellular carcinoma (HCC). Genetic, metabolic, and environmental factors strongly contribute to the heterogeneity of MASLD. Lifestyle intervention and weight loss represent a viable treatment for MASLD. Moreover, Resmetirom, a thyroid hormone beta receptor agonist, has recently been approved for MASLD treatment. However, most individuals treated did not respond to this therapeutic, suggesting the need for a more tailored approach to treat MASLD. Oligonucleotide-based therapies, namely small-interfering RNA (siRNA) and antisense oligonucleotide (ASO), have been recently developed to tackle MASLD by reducing the expression of genes influencing MASH progression, such as PNPLA3 and HSD17B13. Here, we review the latest progress made in the synthesis and development of oligonucleotide-based agents targeting genetic determinants of MASH.

Citations

Citations to this article as recorded by  Crossref logo
  • NSD2 exacerbates metabolic dysfunction-associated steatotic liver disease progression by suppressing TFEB-mediated autophagy-lysosomal pathway
    Yuan Qiao, Yijia Zhang, Cuiting Sun, Qi Jin, Peng Qu, Zecheng Li, Yang Qiu, Hua Meng, Dantao Peng, Liang Peng
    Metabolism.2026; 174: 156416.     CrossRef
  • Unveiling EMC6 as a novel pathogenic determinant in hepatocellular carcinoma: orchestration of lipid metabolism through regulation of lipid droplet-associated enzyme HSD17B13
    Yun Zhang, Chanyu Xiong, Zhilin Jiang, Xiao Wang, Zihao Wang, Junyao Chen, Qiong Li, Yangyang Luo, Xudan Yang, Chen Chu, Shikai Zhu, Xianjun Zhu, Yu Zhou
    Oncogene.2026; 45(2): 322.     CrossRef
  • Cholesterol-dependent control of endosomal escape regulates intracellular trafficking of small interfering RNA therapeutics and interactions with small molecule drugs
    Sherouk M. Tawfik, Le Tra Giang Nguyen, Jing Jin, Beshoy Armanios, Xiao-bo Zhong
    The Journal of Pharmacology and Experimental Therapeutics.2026; 393(2): 103802.     CrossRef
  • Immune Determinants of MASLD Progression: From Immunometabolic Reprogramming to Fibrotic Transformation
    Senping Xu, Zhaoshan Zhang, Zhongquan Zhou, Jiawei Guo
    Biology.2026; 15(2): 148.     CrossRef
  • Rodent model of metabolic dysfunction‐associated fatty liver disease: a systematic review
    Xiao‐Shan Cui, Hong‐Zheng Li, Liang Li, Cheng‐Zhi Xie, Jia‐Ming Gao, Yuan‐Yuan Chen, Hui‐Yu Zhang, Wei Hao, Jian‐Hua Fu, Hao Guo
    Journal of Gastroenterology and Hepatology.2025; 40(1): 48.     CrossRef
  • Role of PNPLA3 in Hepatic Stellate Cells and Hepatic Cellular Crosstalk
    Maria Castanho Martins, Emmanuel Dauda Dixon, Giulia Lupo, Thierry Claudel, Michael Trauner, Krista Rombouts
    Liver International.2025;[Epub]     CrossRef
  • Novel Therapies for Nonalcoholic Steatohepatitis (NASH) and Cardiovascular Risk Reduction
    Tarun Biswas, Angelica Lehker, Debabrata Mukherjee
    Cardiovascular & Hematological Disorders-Drug Targets.2025; 24(4): 211.     CrossRef
  • Liver-specific inactivation of Cideb improves metabolic profiles and ameliorates steatohepatitis and fibrosis in animal models for MASH
    Jianhua Zhang, Xujie Liu, Xian Jin, Xudong Mao, Xueli Xu, Xing Zhang, Ke Shang, Yuan Xu, Yanhuan Zhang, Guofeng Meng, Ming Yue, Guoqing Cai, Song Yang, Jinyu Huang, Jianwu Fang, Ling Pan, Lei Jiang, Stella Shi, Jianyong Shou
    Pharmacological Research.2025; 214: 107664.     CrossRef
  • Circadian control of hepatic ischemia/reperfusion injury via HSD17B13-mediated autophagy in hepatocytes
    Hui Wang, Meina Guo, Baoyin Ren, Haibo Zhang, Jiayang Zhang, Rongfang Qiao, Lei Qian, Jingwen Zhu, Shuying Zhang, Wen Su, Xiaoyan Zhang, Guangrui Yang, Youfei Guan, Lihong Chen
    Journal of Hepatology.2025; 83(3): 750.     CrossRef
  • Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis
    Wenya Zhu, Jialing Ma, Tingting Zhang, Mengmeng Zhu, Yajun Duan, Xiaoxiao Yang, Yuanli Chen
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Hepatocyte nuclear factor 4-Alpha: a key regulator in liver carcinogenesis
    Hayam Hamdy, Chang Shen, Jiashun Xu, Die Fan, Yiwen Zhang, Hui Li, Yonglong Wei, Jianwei Sun
    Cellular Oncology.2025; 48(4): 885.     CrossRef
  • Targeting CIDEB alleviates liver steatosis and fibrosis in mouse MASH models
    Yingying Lin, Fushun Fan, Zhenxian Mo, Ziyang Huang, Minhua Zhou, Yaru Ma, Chuiwen Qian, Yifei Wang, Changgeng Qian, Xinjian Liu
    Molecular Therapy Nucleic Acids.2025; 36(2): 102567.     CrossRef
  • Polygenic Risk Score for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis: A Narrative Review
    Tatsuo Kanda, Reina Sasaki-Tanaka, Hiroyuki Abe, Naruhiro Kimura, Tomoaki Yoshida, Kazunao Hayashi, Akira Sakamaki, Takeshi Yokoo, Hiroteru Kamimura, Atsunori Tsuchiya, Kenya Kamimura, Shuji Terai
    International Journal of Molecular Sciences.2025; 26(11): 5164.     CrossRef
  • Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation
    Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang
    Advanced Science.2025;[Epub]     CrossRef
  • Emerging therapies and real-world application of metabolic dysfunction-associated steatotic liver disease treatment
    Hee Yeon Kim, Mary E. Rinella
    Clinical and Molecular Hepatology.2025; 31(3): 753.     CrossRef
  • Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy
    Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Zhongsha Li, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Wei Su, Mingzhu Yin
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • The Distribution and Survival Association of Genetic Polymorphisms in Thai Patients with Hepatocellular Carcinoma According to Underlying Liver Disease
    Theint Cho Zin Aung, Bootsakorn Boonkaew, Maneerat Chayanupatkul, Kittiyod Poovorawan, Natthaya Chuaypen, Pisit Tangkijvanich
    Genes.2025; 16(7): 808.     CrossRef
  • Editorial: Time to Genotype—Genetic Risk and Prognosis in Steatotic Liver Disease
    Rosellina M. Mancina, Stefano Romeo
    Alimentary Pharmacology & Therapeutics.2025; 62(8): 841.     CrossRef
  • Human genetics of steatotic liver disease: insights into insulin resistance and lipid metabolism
    Rosellina M. Mancina, Luca Valenti, Stefano Romeo
    Nature Metabolism.2025; 7(11): 2199.     CrossRef
  • Lysosome-Targeting Chimeras: Design, Mechanisms, and Degradation of “Rogue” Proteins
    Muneeb Ur Rehman, Xinxi Wu, Qun Chen, Ziwei Liu, Sihui Long
    Bioorganic Chemistry.2025; 167: 109249.     CrossRef
  • Pharmacotherapy of Liver Fibrosis and Hepatitis: Recent Advances
    Liangtao Zhao, Haolan Tang, Zhangjun Cheng
    Pharmaceuticals.2024; 17(12): 1724.     CrossRef
  • 12,682 View
  • 522 Download
  • 18 Web of Science
  • Crossref

Steatotic liver disease

Taiwan Association for the Study of the Liver-Taiwan Society of Cardiology Taiwan position statement for the management of metabolic dysfunction- associated fatty liver disease and cardiovascular diseases
Pin-Nan Cheng, Wen-Jone Chen, Charles Jia-Yin Hou, Chih-Lin Lin, Ming-Ling Chang, Chia-Chi Wang, Wei-Ting Chang, Chao-Yung Wang, Chun-Yen Lin, Chung-Lieh Hung, Cheng-Yuan Peng, Ming-Lung Yu, Ting-Hsing Chao, Jee-Fu Huang, Yi-Hsiang Huang, Chi-Yi Chen, Chern-En Chiang, Han-Chieh Lin, Yi-Heng Li, Tsung-Hsien Lin, Jia-Horng Kao, Tzung-Dau Wang, Ping-Yen Liu, Yen-Wen Wu, Chun-Jen Liu
Clin Mol Hepatol 2024;30(1):16-36.
Published online October 4, 2023
DOI: https://doi.org/10.3350/cmh.2023.0315
Metabolic dysfunction-associated fatty liver disease (MAFLD) is an increasingly common liver disease worldwide. MAFLD is diagnosed based on the presence of steatosis on images, histological findings, or serum marker levels as well as the presence of at least one of the three metabolic features: overweight/obesity, type 2 diabetes mellitus, and metabolic risk factors. MAFLD is not only a liver disease but also a factor contributing to or related to cardiovascular diseases (CVD), which is the major etiology responsible for morbidity and mortality in patients with MAFLD. Hence, understanding the association between MAFLD and CVD, surveillance and risk stratification of MAFLD in patients with CVD, and assessment of the current status of MAFLD management are urgent requirements for both hepatologists and cardiologists. This Taiwan position statement reviews the literature and provides suggestions regarding the epidemiology, etiology, risk factors, risk stratification, nonpharmacological interventions, and potential drug treatments of MAFLD, focusing on its association with CVD.

Citations

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  • FIB‐4 Serves as a Referral Index for Coronary Artery Calcification in Patients With MASLD
    Ya‐Chin Huang, Chih‐Wen Wang, Jiun‐Chi Huang, Po‐Cheng Liang, Ming‐Lun Yeh, Yi‐Yu Chen, Yi‐Hung Lin, Tyng‐Yuan Jang, Yu‐Ju Wei, Ming‐Yen Hsieh, Chao‐Kuan Huang, Hsu‐Han Chien, Chia‐Jen Wu, Jee‐Fu Huang, Chia‐Yen Dai, Wan‐Long Chuang, Chia‐I Lin, Chung‐Fen
    Journal of Gastroenterology and Hepatology.2026; 41(1): 332.     CrossRef
  • Serum mir-181a as a potential serological biomarker for metabolic dysfunction-associated fatty liver disease: A cross sectional study
    Ke-Gong Xiong, Jin-Feng Kong, Tai-Shun Lin, Qing-Biao Lin, Kun-Yu Ke
    Medicine.2026; 105(4): e47290.     CrossRef
  • A machine learning model to predict liver-related outcomes after the functional cure of chronic hepatitis B
    Moon Haeng Hur, Terry Cheuk-Fung Yip, Seung Up Kim, Hyun Woong Lee, Han Ah Lee, Hyung-Chul Lee, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Jun Yong Park, Sang Hoon Ahn, Beom Kyung Kim, Hwi Young Kim, Yeon Seok Seo, Hyunjae Shin, Jeayeon Park, Yunmi Ko, Yo
    Journal of Hepatology.2025; 82(2): 235.     CrossRef
  • Reply to: “A machine learning model to predict liver-related outcomes after the functional cure of chronic hepatitis B: Is cirrhosis driving the performance?”
    Moon Haeng Hur, Jeong-Hoon Lee
    Journal of Hepatology.2025; 82(3): e143.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease is Associated with Increased Risks of Heart Failure
    Kai-Chun Chang, Tung-Hung Su, Cho-Kai Wu, Shang-Chin Huang, Tai-Chung Tseng, Chun-Ming Hong, Shih-Jer Hsu, Chen-Hua Liu, Hung-Chih Yang, Chun-Jen Liu, Jia-Horng Kao
    European Journal of Heart Failure.2025; 27(3): 512.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and its associated health risks
    Xia-Rong Liu, Szu-Ching Yin, Yi-Ting Chen, Mei-Hsuan Lee
    Journal of the Chinese Medical Association.2025; 88(5): 343.     CrossRef
  • Fatty Liver and Hyperuricemia in Workers: Combined Effects on Metabolic Dysfunction and the Role of Lifestyle Factors
    Jui-Hua Huang, Ren-Hau Li, Hon-Ke Sia, Feng-Cheng Tang
    Metabolites.2025; 15(5): 318.     CrossRef
  • Application of insulin resistance score in type 2 diabetes mellitus complicated with fatty liver and liver fibrosis
    Shaojie Duan, Mengdie Chen, Jie Chen, Yaojian Shao, Xiaolong Jin, Chaohui Wang, Ping Feng, Xiaosheng Teng, Zhenjun Yu
    European Journal of Gastroenterology & Hepatology.2025; 37(10): 1155.     CrossRef
  • The role of Bergamot Polyphenolic Fraction (BPF) in MASLD-Induced HFpEF: Mitigate diastolic dysfunction by targeting chronic low-grade inflammation
    Cristina Carresi, Antonio Cardamone, Vincenzo Musolino, Rocco Mollace, Annamaria Tavernese, Anna Rita Coppoletta, Micaela Gliozzi, Vincenzo Mollace
    Biomedicine & Pharmacotherapy.2025; 190: 118375.     CrossRef
  • Advanced Fibrosis and Cardiometabolic Risk Burden Increase Major Cardiovascular Events in Chronic Hepatitis C Patients With Steatotic Liver Disease After Viral Eradication
    Pei‐Chien Tsai, Chung‐Feng Huang, Ming‐Lun Yeh, Yu‐Ju Wei, Chih‐Wen Wang, Tyng‐Yuan Jang, Po‐Cheng Liang, Yi‐Hung Lin, Chia‐Yen Dai, Jee‐Fu Huang, Wan‐Long Chuang, Ming‐Lung Yu
    Alimentary Pharmacology & Therapeutics.2025;[Epub]     CrossRef
  • Cardiovascular risk of tenofovir disoproxil fumarate or tenofovir alafenamide in patients with chronic hepatitis B: More questions than an answer
    Pin-Nan Cheng, Ming-Lung Yu
    Clinical and Molecular Hepatology.2024; 30(2): 144.     CrossRef
  • MAFLD: from a disease framework to patient care
    Mohammed Eslam, Jacob George
    Hepatology International.2024; 18(S2): 823.     CrossRef
  • Effect of metabolic dysfunction on the risk of liver-related events in patients cured of hepatitis C virus
    Wei-Fan Hsu
    American Journal of Cancer Research.2024; 14(4): 1914.     CrossRef
  • The unfolded features on the synchronized fashion of gut microbiota and Drynaria rhizome against obesity via integrated pharmacology
    Ki-Kwang Oh, Sang-Jun Yoon, Seol Hee Song, Jeong Ha Park, Jeong Su Kim, Min Ju Kim, Dong Joon Kim, Ki-Tae Suk
    Food Chemistry.2024; 460: 140616.     CrossRef
  • High sensitivity troponins and mortality in the population with metabolic dysfunction-associated steatotic liver disease
    Jingjing Hu, Yuteng Du, Yidan Zhou, Huiying Wang
    Scientific Reports.2024;[Epub]     CrossRef
  • MASLD: an emerging factor in the pathophysiology and clinical management of ICC
    Zong-Long Li, Jia-Lu Chen, Yue Tang, De-Long Qin, Zhao-Hui Tang
    Hepatoma Research.2024;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease: bridging cardiology and hepatology
    Xiao-Dong Zhou, Giovanni Targher, Christopher D. Byrne, Michael D. Shapiro, Li-Li Chen, Ming-Hua Zheng
    Cardiology Plus.2024; 9(4): 275.     CrossRef
  • 11,804 View
  • 379 Download
  • 22 Web of Science
  • Crossref

Editorials

Steatotic liver disease

Adding to the confusion in more than just the name
Jacob George
Clin Mol Hepatol 2023;29(4):973-976.
Published online September 18, 2023
DOI: https://doi.org/10.3350/cmh.2023.0367

Citations

Citations to this article as recorded by  Crossref logo
  • Dietary ω-3 polyunsaturated fatty acid intake improves skeletal muscle mass in patients with metabolic dysfunction-associated fatty liver disease: A nationwide cross-sectional study
    Li-Zhan Bie, Chao Wu, Jia-Lu Wang
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Managing MASLD Through Preventive Hepatology: Integrating Policy Reform, Public Health and Personalised Care
    Zobair M. Younossi, Vincent Wai‐Sun Wong, Emmanuel A. Tsochatzis, Laurent Castera, Michael Betel, Linda Henry, Shira Zelber Sagi
    Liver International.2025;[Epub]     CrossRef
  • Steatotic liver disease, MASLD and risk of chronic kidney disease
    Josh Bilson, Alessandro Mantovani, Christopher D. Byrne, Giovanni Targher
    Diabetes & Metabolism.2024; 50(1): 101506.     CrossRef
  • Impact of MAFLD criteria on postoperative recurrence of non-B, non-C HCC
    Yusuke Johira, Takashi Nakahara, Kenji Yamaoka, Yasutoshi Fujii, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Shiro Oka
    European Journal of Gastroenterology & Hepatology.2024; 36(4): 430.     CrossRef
  • Progress is impossible without change: understanding the evolving nomenclature of steatotic liver disease and its effect on hepatology practice
    Paul N Brennan, Oliver D Tavabie, Wenhao Li, Thomas Marjot, Lynsey Corless, Jonathan A Fallowfield, Helen Jarvis, Dina Mansour, Stuart McPherson, William Rosenberg, Karen Rockell, Jeremy Tomlinson, Andrew Yeoman, Emmanuel A Tsochatzis, John F Dillon, Will
    The Lancet Gastroenterology & Hepatology.2024; 9(6): 577.     CrossRef
  • Does an Aspirin a Day Take the MASLD Away?
    Amedeo Lonardo, Ming-Hua Zheng
    Advances in Therapy.2024; 41(7): 2559.     CrossRef
  • Neuroimmune modulation in liver pathophysiology
    Ju Zou, Jie Li, Xiaoxu Wang, Daolin Tang, Ruochan Chen
    Journal of Neuroinflammation.2024;[Epub]     CrossRef
  • Letter regarding “Waiting for the changes after the adoption of steatotic liver disease”
    Kuo Chao Yew, Sunny H. Wong, Vincent Wai-Sun Wong, Hazel H. Oon
    Clinical and Molecular Hepatology.2023; 30(1): 118.     CrossRef
  • 5,582 View
  • 89 Download
  • 8 Web of Science
  • Crossref

Steatotic liver disease

Citations

Citations to this article as recorded by  Crossref logo
  • FIB‐4 Serves as a Referral Index for Coronary Artery Calcification in Patients With MASLD
    Ya‐Chin Huang, Chih‐Wen Wang, Jiun‐Chi Huang, Po‐Cheng Liang, Ming‐Lun Yeh, Yi‐Yu Chen, Yi‐Hung Lin, Tyng‐Yuan Jang, Yu‐Ju Wei, Ming‐Yen Hsieh, Chao‐Kuan Huang, Hsu‐Han Chien, Chia‐Jen Wu, Jee‐Fu Huang, Chia‐Yen Dai, Wan‐Long Chuang, Chia‐I Lin, Chung‐Fen
    Journal of Gastroenterology and Hepatology.2026; 41(1): 332.     CrossRef
  • Cardiovascular Risk From Metabolic Dysfunction-Associated Steatotic Liver Disease, Cardiometabolic Risk Factor Count, and Their Longitudinal Changes: A Nationwide Cohort Study
    Hyeok-Hee Lee, Han Ah Lee, Eun-Jin Kim, Hwi Young Kim, Hyeon Chang Kim, Sang Hoon Ahn, Hokyou Lee, Seung Up Kim
    American Journal of Gastroenterology.2025; 120(10): 2321.     CrossRef
  • Non-Invasive Liver Fibrosis Test Using Shear Wave Elastography
    Ji Won Han
    The Korean Journal of Medicine.2025; 100(1): 26.     CrossRef
  • Mitochondrial mt12361A>G increased risk of metabolic dysfunction-associated steatotic liver disease among non-diabetes
    Ming-Ying Lu, Yu-Ju Wei, Chih-Wen Wang, Po-Cheng Liang, Ming-Lun Yeh, Yi-Shan Tsai, Pei-Chien Tsai, Yu-Min Ko, Ching-Chih Lin, Kuan-Yu Chen, Yi-Hung Lin, Tyng-Yuan Jang, Ming-Yen Hsieh, Zu-Yau Lin, Chung-Feng Huang, Jee-Fu Huang, Chia-Yen Dai, Wan-Long Ch
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • Unlocking the potential of THR-β agonist therapies: resmetirom’s chemistry, biology, and patent insights
    Khushi Dahiya, Mahesh Palkar, Sanjay Sharma
    Naunyn-Schmiedeberg's Archives of Pharmacology.2025; 398(8): 9703.     CrossRef
  • Shared genetic architecture between metabolic dysfunction-associated steatotic liver disease and cardiometabolic traits comorbidities: a genome-wide pleiotropic and multi-omics study
    Xuan-Yu Wang, Qiong Lyu, Yang-Yang Zhang, Yue Su, Hongjie Zhao, Hui-Hui Shen, Ying-Yu Xie
    Metabolism and Target Organ Damage.2025;[Epub]     CrossRef
  • From cooperation to collapse: systemic failure in liver disease through a sociological lens
    Junyu Wang, Jingting Lei, Martin C. Harmsen, Han Moshage
    Exploration of Digestive Diseases.2025;[Epub]     CrossRef
  • Sustainable HPLC Method for Resmetirom, a Novel THR-β Agonist: Development, Validation and Greenness Assessment
    Khushi Dahiya, Sanjay Sharma
    Chromatographia.2025; 88(9): 717.     CrossRef
  • Integrated stress response-mediated metabolic reprogramming drives hepatic stellate cell activation and liver fibrosis via the noncanonical EIF3d-ATF4-S100P signaling pathway
    Simin Yang, Hongli Zhang, Xiaoyan Sun, Zhengyang Chen, Zhentian Nie, Yuting Li, Xiaohan Liu, Yawei Kong, Ziyu Wang, Wenjing Zai, Shan Gao, Wei Chen
    Redox Biology.2025; 88: 103905.     CrossRef
  • Gut microbiota-derived indole compounds attenuate metabolic dysfunction-associated steatotic liver disease by improving fat metabolism and inflammation
    Byeong Hyun Min, Shivani Devi, Goo Hyun Kwon, Haripriya Gupta, Jin-Ju Jeong, Satya Priya Sharma, Sung-Min Won, Ki-Kwang Oh, Sang Jun Yoon, Hee Jin Park, Jung A Eom, Min Kyo Jeong, Ji Ye Hyun, Nattan Stalin, Tae-Sik Park, Jieun Choi, Do Yup Lee, Sang Hak H
    Gut Microbes.2024;[Epub]     CrossRef
  • From Nonalcoholic Fatty Liver Disease to Metabolic Dysfunction-Associated Steatotic Liver Disease: Out with the Old, in with the New
    Iyiad Alabdul Razzak, Mazen Noureddin, Hirsh Trivedi
    Journal of Clinical Medicine.2024; 13(3): 880.     CrossRef
  • Impact of MAFLD criteria on postoperative recurrence of non-B, non-C HCC
    Yusuke Johira, Takashi Nakahara, Kenji Yamaoka, Yasutoshi Fujii, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Shiro Oka
    European Journal of Gastroenterology & Hepatology.2024; 36(4): 430.     CrossRef
  • TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
    Roi Isaac, Gautam Bandyopadhyay, Theresa V. Rohm, Sion Kang, Jinyue Wang, Narayan Pokhrel, Sadatsugu Sakane, Rizaldy Zapata, Avraham M. Libster, Yaron Vinik, Asres Berhan, Tatiana Kisseleva, Zea Borok, Yehiel Zick, Francesca Telese, Nicholas J.G. Webster,
    Cell Metabolism.2024; 36(5): 1030.     CrossRef
  • Dual-etiology MAFLD: the interactions between viral hepatitis B, viral hepatitis C, alcohol, and MAFLD
    Chun-Jen Liu, Wai Kay Seto, Ming-Lung Yu
    Hepatology International.2024; 18(S2): 897.     CrossRef
  • Collagen-rich liver-derived extracellular matrix hydrogels augment survival and function of primary rat liver sinusoidal endothelial cells and hepatocytes
    Junyu Wang, Fenghua Zhao, Linda A. Brouwer, Manon Buist-Homan, Justina C. Wolters, Han Moshage, Martin C. Harmsen
    International Journal of Biological Macromolecules.2024; 278: 134717.     CrossRef
  • Incretin-based therapy in the management of metabolic dysfunction-associated steatotic liver disease (MASLD): one piece of the puzzle: Editorial on “Comparison of glucagon-like peptide-1 receptor agonists and thiazolidinediones on treating nonalcoholic fa
    Tian-Yi Ren, Mohammed Eslam, Jian-Gao Fan
    Clinical and Molecular Hepatology.2024; 30(4): 649.     CrossRef
  • Pathogenesis and management of metabolic dysfunction-associated steatohepatitis-related hepatocellular carcinoma: a narrative review
    Han Ah Lee
    The Ewha Medical Journal.2024;[Epub]     CrossRef
  • 7,680 View
  • 198 Download
  • 16 Web of Science
  • Crossref
Review

Steatotic liver disease

MAFLD: How is it different from NAFLD?
Cameron Gofton, Yadhavan Upendran, Ming-Hua Zheng, Jacob George
Clin Mol Hepatol 2023;29(Suppl):S17-S31.
Published online November 29, 2022
DOI: https://doi.org/10.3350/cmh.2022.0367
“Metabolic dysfunction-associated fatty liver disease (MAFLD)” is the term suggested in 2020 to refer to fatty liver disease related to systemic metabolic dysregulation. The name change from nonalcoholic fatty liver disease (NAFLD) to MAFLD comes with a simple set of criteria to enable easy diagnosis at the bedside for the general medical community, including primary care physicians. Since the introduction of the term, there have been key areas in which the superiority of MAFLD over the traditional NAFLD terminology has been demonstrated, including for the risk of liver and extrahepatic mortality, disease associations, and for identifying high-risk individuals. Additionally, MAFLD has been adopted by a number of leading pan-national and national societies due to its concise diagnostic criterion, removal of the requirement to exclude concomitant liver diseases, and reduction in the stigma associated with this condition. The current article explores the differences between MAFLD and NAFLD diagnosis, areas of benefit, some potential limitations, and how the MAFLD terminology has opened up new fields of research.

Citations

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  • Astragaloside IV alleviates metabolic associated fatty liver disease by regulating ferroptosis via the SLC7A11/GPX4 pathway
    Sitong CHEN, Hanying XU, Zipei ZHANG, Xiaonan LI, Xiaolei TANG, Dashi YING
    Chinese Journal of Analytical Chemistry.2026; 54(2): 100625.     CrossRef
  • Associations between per- and polyfluoroalkyl substances and metabolic dysfunction-associated steatotic liver disease in adolescents and young adults: modifying roles of age, lifestyle factors, and PNPLA3 genotype
    Shiwen Li, Jiawen Carmen Chen, Elizabeth Costello, Douglas I. Walker, Jesse A. Goodrich, Lily Dara, Lucy Golden-Mason, Ana C. Maretti-Mira, Scott M. Bartell, Veronica M. Vieira, Tanya L. Alderete, Michael I. Goran, Zhanghua Chen, Frank D. Gilliland, Britt
    Environmental Research.2026; 288: 123320.     CrossRef
  • Assessment of the Diagnostic Performance and Clinical Impact of AI in Hepatic Steatosis: Systematic Review and Meta-Analysis
    Jiamei Song, Dan Liu, Jitong Li, Haoru Cong, Ruixue Deng, Yihan Lu, Jiayi Sun, Jingzhou Zhang
    Journal of Medical Internet Research.2026; 28: e78310.     CrossRef
  • A multicenter trial to test pitavastatin calcium in youth with combined dyslipidemia of obesity: Design, implementation, challenges, and responses
    Sarah D. de Ferranti, Jessica E. Teng, Silva A. Arslanian, Andrew M. Atz, Julie A. Brothers, Mark J. Cartoski, D’Andrea R. Freemon, Sheela N. Magge, William T. Mahle, Michele Mietus-Snyder, Amy Peterson, Geetha Raghuveer, Mark W. Russell, Amy S. Shah, Cra
    American Heart Journal.2026; 294: 107327.     CrossRef
  • A systematic review of MicroRNA (miRNA) biomarkers in the diagnosis and prognosis of hepatocellular carcinoma
    J. M. John Britto, T Beula Bell
    Irish Journal of Medical Science (1971 -).2026;[Epub]     CrossRef
  • Organ cross-talk: molecular mechanisms, biological functions, and therapeutic interventions for diseases
    Huiting Che, Yidan Gao, Yonghu Xu, Hui Xu, Roland Eils, Mei Tian
    Signal Transduction and Targeted Therapy.2026;[Epub]     CrossRef
  • Prevalence and importance of periodontal disease in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) in Veracruz
    L. Roesch-Ramos, D.N. Guzmán-Uzcanga, S. Nolasco-Polito, S. Pérez-Pérez, F. Moreno-Marín, R.M. Francisco, H.R. Ordaz-Álvarez, F.B. Roesch-Dietlen, J.M. Remes-Troche, A.D. Cano-Contreras
    Revista de Gastroenterología de México (English Edition).2026;[Epub]     CrossRef
  • Subtype-specific associations of steatotic liver disease with gastric and esophageal cancers: a nationwide cohort study
    Yeo Wool Kang, Minkook Son, Jong Yoon Lee, Sang Yi Moon, Myeongseok Koh
    Gastric Cancer.2026;[Epub]     CrossRef
  • Gpx4 Deletion‐Mediated Macrophage Ferroptosis Alleviates Obesity‐Associated Insulin Resistance
    Suhua Wu, Juan Peng, Xiaodong Wang, Hong Gao, Huangrui Fang, Shiyi Hu, Qiufen Wei, Yuanye Dang, Haixia Tu, Mingyan Zhu, Jianye Peng, Yumiao Liu, Gaofeng Zeng, Xiaoyan Dai
    The FASEB Journal.2026;[Epub]     CrossRef
  • Combination of GLP-1 receptor agonist and Akkermansia muciniphila Akk11 reduces adiposity and ameliorates MASLD in T2D mice
    Kaige Gao, Zaifei Yin, Chi Zhang, Zixuan Dong, Runqi Wang, Qian Chen, Xiangpeng Liu, Caifeng Jiang, Yalin Wang, Bin Guo, Zhengyu Zhou, Zhihao Jia, Hong Sun, Yu Feng
    Cell & Bioscience.2026;[Epub]     CrossRef
  • Choline Deficiency Drives the Inflammation–Fibrosis Cascade: A Spatiotemporal Atlas of Hepatic Injury from Weeks 6 to 10
    Shang Li, Guoqiang Zhang, Xiaohong Li, Xu Zhao, Axi Shi, Qingmin Dong, Changpeng Chai, Xiaojing Song, Yuhui Wei, Xun Li
    Antioxidants.2026; 15(1): 110.     CrossRef
  • Using Large Language Models to Predict Advanced Liver Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Proof-of-Concept Analysis
    Basile Njei, Nelvis Njei, Sarpong Boateng, Omar Al Ta'ani, Yazan Al-Ajlouni
    Cureus.2026;[Epub]     CrossRef
  • Gestational Arsenic Exposure Induces Metabolic Dysfunction-Associated Fatty Liver Disease–like Phenotypes in Middle-Aged Offspring
    Qian-Qun Yang, Qing-Hua Qian, Wei-Wei Zhang, Ya-Ping Song, Qing-Yuan Huang, Xue Lu, Tao Wang, Yi-Chao Huang, De-Xiang Xu
    Environment & Health.2026;[Epub]     CrossRef
  • Network Pharmacology-Based Investigation of the Mechanism of Liupao Tea Polyphenol Extract in Preventing MAFLD via the Hepatic EGFR–AKT Pathway
    Jirui Wei, Xiaozheng He, Tingting Shi, Xiayu Jin, Jun Huang, Qingyao Du, Junda Huang, Tao Li, Xunjie Xie, Yuxin Huang, Chengtao Nie, Yiqi Fan, Xixiao Yang, Luyao Song, Waijiao Tang
    Journal of Agricultural and Food Chemistry.2026;[Epub]     CrossRef
  • Procyanidin B2 and an autochthonous apple pulp extract modulate oxidative stress and PPARγ expression on an in vitro model of lipid steatosis in HepG2 cells
    Adrián Millán-Laleona, Marta Lopez-Yus, Silvia Lorente-Cebrián, Jose M. Arbones-Mainar, Carlota Gómez-Rincón, Víctor López
    Journal of Physiology and Biochemistry.2026;[Epub]     CrossRef
  • The Role of Kupffer Cells and Liver Macrophages in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease
    Ioannis Tsomidis, Angeliki Tsakou, Argyro Voumvouraki, Elias Kouroumalis
    Biomedicines.2026; 14(1): 151.     CrossRef
  • Integrating body composition analysis and machine learning for non-invasive identification of metabolic dysfunction-associated fatty liver disease: a large-scale health examination-based study
    Yaxuan He, Yu Cao, Zekai Chen, Rong Xiang, Fang Wang
    Scientific Reports.2026;[Epub]     CrossRef
  • Plasma GLP-1 (Glucagon-like Peptide-1) Depletion Is Correlated with Dysregulation of Adipocytokine in Type 2 Diabetic Patients With or Without Metabolic-Associated Fatty Liver Disease (MAFLD): A Cross-Sectional Study Related to Gender-Sex Disparities
    Zoubiri Houda, Saiah Wassila, Otmane Amel, Saidi Hamza, Makrelouf Mohamed, Aitabderrhmane Samir, Haddam Ali El Mahdi, Koceir Elhadj-Ahmed
    International Journal of Molecular Sciences.2026; 27(3): 1218.     CrossRef
  • Mediating role of metabolic dysfunction-associated fatty liver disease in the association between individual-level noise exposure and liver enzymes in Chinese automotive manufacturing workers
    Sijia Ou, Jiaheng Yu, Zhaoqian Chen, Yanmei Ruan, Xing Rong, Zejin Ou, Yuxia Zhang, Haijuan Huang, Jiaxin Cui, Zhi Wang
    International Archives of Occupational and Environmental Health.2026;[Epub]     CrossRef
  • Efficacy of selected dietary supplements and pharmacological agents on metabolic and oxidative stress outcomes in metabolic dysfunction–associated fatty liver disease (MAFLD): a Bayesian network meta-analysis
    Yunyi Yang, Xiaoli He, Jiayuan Cai, Xiaoxiao Qu, Shufa Tan, Jiawen You, Yanming He, Zheng Yao, Hongjie Yang
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • Efficacy and safety of lower-carbohydrate dietary patterns for metabolic associated fatty liver disease: evidence from randomized controlled trials with grade analysis
    Yunhang Chu, Ming Yang, Qi Meng, Delong Cong, Lingyu Xu, Peng Dai, Ziqiang Chen, Sulan Chen, Rui Zhang, Yan Leng
    Nutrition & Metabolism.2026;[Epub]     CrossRef
  • Risk Assessment for Carotid Atherosclerosis in Asymptomatic Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease
    Hana Park, Ji Young Lee, Sungwon Park, Hyo Jeong Lee, Suh Eun Bae, Jaeil Kim, Hye-Sook Chang, Jaewon Choe, Hye Won Park, Ju Hyun Shim
    Gut and Liver.2026; 20(1): 125.     CrossRef
  • Research on the Therapeutic Effect and Mechanism of Stir-Roasted Deer Velvet Antler with Ghee on Non-Alcoholic Fatty Liver Disease
    Xuan He, Yinghan Liu, Shuning Cui, Zhenming Yu, Zhongmei He, Ying Zong, Weijia Chen, Jianan Geng, Jia Zhou, Zhuo Li, Yan Zhao, Hongbo Teng
    Nutrients.2026; 18(3): 401.     CrossRef
  • Hepatoprotective Ergostane and Lanostane Derivatives from Mushrooms for the Management of Metabolic Dysfunction-Associated Fatty Liver Disease: A Review
    K.Razak Deen, S. Rithick, M. Muthumari, D. Jayakumar, N. Amrith Sam, K. Balakrishna, Perumal Pandikumar, Savarimuthu Ignacimuthu
    International Journal of Medicinal Mushrooms.2026; 28(2): 1.     CrossRef
  • Liver Cancer Risk Across Metabolic Dysfunction-Associated Steatotic Liver Disease and/or Alcohol: A Nationwide Study
    Byungyoon Yun, Heejoo Park, Sang Hoon Ahn, Juyeon Oh, Beom Kyung Kim, Jin-Ha Yoon
    American Journal of Gastroenterology.2025; 120(2): 410.     CrossRef
  • La phospholipase A2 associée aux lipoprotéines (Lp-PLA2) : biomarqueur pertinent et cible thérapeutique ?
    Dominique Bonnefont-Rousselot
    Annales Pharmaceutiques Françaises.2025; 83(1): 45.     CrossRef
  • Comparing Three Ultrasound-Based Techniques for Diagnosing and Grading Hepatic Steatosis in Metabolic Dysfunction-Associated Steatotic Liver Disease
    Pingping Wang, Danlei Song, JiaHao Han, Jing Zhang, Huihui Chen, Ruixia Gao, Huiming Shen, Jia Li
    Academic Radiology.2025; 32(4): 1949.     CrossRef
  • The Effect of Curcumin on Glucolipid Metabolic Disorders: A Review
    Lifen Mo, Siyu Wan, Tekla Zékány-Nagy, Xiaoyi Luo, Xingfen Yang
    Food Reviews International.2025; 41(2): 543.     CrossRef
  • Unveiling the nexus: pyroptosis and its crucial implications in liver diseases
    Zeyu Miao, Xiaorong Zhang, Yang Xu, Yan Liu, Qing Yang
    Molecular and Cellular Biochemistry.2025; 480(4): 2159.     CrossRef
  • MASLD, MLA Pesarattu and Other Developments
    Anil C. Anand
    Journal of Clinical and Experimental Hepatology.2025; 15(1): 102465.     CrossRef
  • Elevated concurrent carotid atherosclerosis rates in patients with metabolic dysfunction-associated fatty liver disease (MAFLD) compared to non-alcoholic fatty liver disease (NAFLD): A cross-sectional observational study
    Nien-Ting Chung, Chiann-Yi Hsu, Nai-Chen Shih, Jia-Jyun Wu
    Nutrition, Metabolism and Cardiovascular Diseases.2025; 35(1): 103767.     CrossRef
  • Sex Hormone: A Potential Target at Treating Female Metabolic Dysfunction-Associated Steatotic Liver Disease?
    Huiyan Duan, Minmin Gong, Gang Yuan, Zhi Wang
    Journal of Clinical and Experimental Hepatology.2025; 15(2): 102459.     CrossRef
  • Impact of Nonalcoholic Fatty Liver Disease on Weight Loss Outcomes After One Anastomosis Gastric Bypass
    Rahmatullah Athar, Masoumeh Shahsavan, Shahab Shahabi, Abdolreza Pazouki, Farah A. Husain, Mohammad Kermansaravi
    Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2025;[Epub]     CrossRef
  • Trehalose Ameliorates Nonalcoholic Fatty Liver Disease by Regulating IRE1α–TFEB Signaling Pathway
    Shan Su, Xiaohong Liu, Min Zhu, Wen Liu, Jingyi Liu, Yujia Yuan, Fudong Fu, Zhiyong Rao, Jingping Liu, Yanrong Lu, Younan Chen
    Journal of Agricultural and Food Chemistry.2025; 73(1): 521.     CrossRef
  • Deterioration of endothelial function as a risk factor for osteoporosis in patients with type 2 diabetes mellitus and MAFLD
    Alexander E. Berezin
    Acta Cardiologica.2025; 80(1): 99.     CrossRef
  • Vitamin D supplementation alleviates high fat diet-induced metabolic associated fatty liver disease by inhibiting ferroptosis pathway
    Yufan Miao, Zhongyan Jiang, Hanlu Song, Yujing Zhang, Hao Chen, Wenyi Liu, Xiaonuo Wei, Longkang Li, Wenjie Li, Xing Li
    European Journal of Nutrition.2025;[Epub]     CrossRef
  • Fermented rhubarb alleviates metabolic dysfunction-associated steatotic liver disease symptoms by modulating gut microbiota and activating the hepatic insulin signaling pathway
    Heng Yuan, Junyu Zhou, Ting Zhang, Xuangao Wu, Chen Li, Hee-Jong Yang, Do Yeon Jeong, Sunmin Park
    Food Bioscience.2025; 63: 105720.     CrossRef
  • Quercetin alleviates metabolic-associated fatty liver disease by tuning hepatic lipid metabolism, oxidative stress and inflammation
    Ling Jiang, Rong Yi, Huan Chen, Shuwu Wu
    Animal Biotechnology.2025;[Epub]     CrossRef
  • Valorizing Agro‐Food Waste for Nutraceutical Development: Sustainable Approaches for Managing Metabolic Dysfunction‐Associated Steatotic Liver Disease and Related Co‐Morbidities
    Laura Comi, Claudia Giglione, Fationa Tolaj Klinaku, Federico Pialorsi, Valentina Tollemeto, Maria Zurlo, Antonio Seneci, Paolo Magni
    Food Frontiers.2025; 6(2): 670.     CrossRef
  • Inter-organ metabolic interaction networks in non-alcoholic fatty liver disease
    Yu-Hong Fan, Siyao Zhang, Ye Wang, Hongni Wang, Hongliang Li, Lan Bai
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Altered kidney function in fatty liver disease: confronting the “MAFLD-renal syndrome”
    Suleiman Al Ashi, Ali A. Rizvi, Manfredi Rizzo
    Frontiers in Clinical Diabetes and Healthcare.2025;[Epub]     CrossRef
  • Correlation between hepatic steatosis severity diagnosed by ultrasound and metabolic indexes in elderly patients with MAFLD
    Zhitang Liang, Renhao Huang, Lingyun Zhang
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Exposure to a choline-deficient diet during pregnancy and lactation alters the liver transcriptome profile in offspring of dams with fatty liver
    Joanna Mikołajczyk-Stecyna, Ewelina Zuk, Agata Chmurzynska, Malgorzata Blatkiewicz, Karol Jopek, Marcin Rucinski
    Clinical Nutrition ESPEN.2025; 66: 9.     CrossRef
  • miR‐18a‐5p/PXR/SREBP2 Was Involved in MAFLD Associated With Methyl Tert‐Butyl Ether Among Petrol Station Workers
    Hanyun Wang, Mingxiao Guo, Fengtao Cui, Mengdi Li, Xianan Zhang, Wei Gao, Xingqiang Fang, Li Chen, Ye Xin, Yucheng Sun, Piye Niu, Junxiang Ma
    Liver International.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease and risk of nephrolithiasis: a sizeable cross-sectional study
    Shengqi Zheng, Tianchi Hua, Guicao Yin, Wei Zhang, Xiaoxiang Wang, Lezhong Qi, Xiayong Jing, Qibing Fan, Xiaoping Yu, Yifan Li
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Endogenous Ethanol Production in the Human Alimentary Tract: A Literature Review
    Renee Stamation
    Journal of Gastroenterology and Hepatology.2025; 40(4): 783.     CrossRef
  • Serum Lactate Dehydrogenase Is a Novel Predictor for the Severity in the Patients With MAFLD: A Cross-Sectional Study in Hefei, China
    Liang Yu, Shiming Bao, Feng Zhu, Yanyan Xu, Fuqiang Zu, Yanwei Liu, Runbeng Jiang, Song Chen, Wei Chen
    Diabetes, Metabolic Syndrome and Obesity.2025; Volume 18: 345.     CrossRef
  • Research progress of cysteine transporter SLC7A11 in endocrine and metabolic diseases
    Jiaqi Chen, Mengzhu Yuan, Jianping Wang
    Molecular Biology Reports.2025;[Epub]     CrossRef
  • Obesity and Adipose-Derived Extracellular Vesicles: Implications for Metabolic Regulation and Disease
    Michele Malaguarnera, Omar Cauli, Andrea Cabrera-Pastor
    Biomolecules.2025; 15(2): 231.     CrossRef
  • Effects of GLP-1 receptor agonist therapy on resolution of steatohepatitis in non-alcoholic fatty liver disease: a systematic review and meta-analysis
    Kathryn J Potter, Jackie Phinney, Tasha Kulai, Vicki Munro
    Journal of the Canadian Association of Gastroenterology.2025; 8(2): 47.     CrossRef
  • IFN-γ-mediated inhibition of JAK/STAT signaling via nano-scutellarin treatment is an efficient strategy for ameliorating liver fibrosis
    Ting Wang, Bangguo Liu, Juan Huang, Qixin Zhao, Hongping Shen, Tao Bi, Zengjin Liu, Yong Dai, Qin Sun
    Journal of Translational Medicine.2025;[Epub]     CrossRef
  • Is type 2 diabetes a link between lung function and metabolic dysfunction–associated steatotic liver disease? Insights from population studies and Mendelian randomization
    Runmin Cao, Yurun Zhang, Ling Cao, Honghe Jiang
    European Journal of Gastroenterology & Hepatology.2025; 37(5): 652.     CrossRef
  • Current Therapeutic Landscape for Metabolic Dysfunction-Associated Steatohepatitis
    Arun George Devasia, Adaikalavan Ramasamy, Chen Huei Leo
    International Journal of Molecular Sciences.2025; 26(4): 1778.     CrossRef
  • Psychosocial risks in metabolic dysfunction-associated steatotic liver disease
    Hanne Åström, Christine Takami Lageborn, Hannes Hagström
    Expert Review of Gastroenterology & Hepatology.2025; 19(3): 273.     CrossRef
  • Racial Disparities in Mortality Rates among Patients with Hepatic Steatosis, Non-Alcoholic Fatty Liver Disease, and Non-Alcoholic Steatohepatitis: Insights from NHANES III Data
    Shahrzad Bazargan-Hejazi, Cameron Hines, Myra Usmani, Chris Argueta, Deyu Pan, Arleen F. Brown
    Journal of Racial and Ethnic Health Disparities.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease in adults
    Daniel Q. Huang, Vincent W. S. Wong, Mary E. Rinella, Jerome Boursier, Jeffrey V. Lazarus, Hannele Yki-Järvinen, Rohit Loomba
    Nature Reviews Disease Primers.2025;[Epub]     CrossRef
  • A Comprehensive Review of Metabolic Dysfunction-Associated Steatotic Liver Disease: Its Mechanistic Development Focusing on Methylglyoxal and Counterbalancing Treatment Strategies
    Izabela Berdowska, Małgorzata Matusiewicz, Izabela Fecka
    International Journal of Molecular Sciences.2025; 26(6): 2394.     CrossRef
  • A Literature Review of Glutathione Therapy in Ameliorating Hepatic Dysfunction in Non-Alcoholic Fatty Liver Disease
    Michelle Thuy Nguyen, Andrew Lian, Frederick Timothy Guilford, Vishwanath Venketaraman
    Biomedicines.2025; 13(3): 644.     CrossRef
  • Red Meat Amino Acids for Beginners: A Narrative Review
    Benjamin Barr, Danielle E. Levitt, Lauren Gollahon
    Nutrients.2025; 17(6): 939.     CrossRef
  • Clinical Insights into Non-Alcoholic Fatty Liver Disease and the Therapeutic Potential of Flavonoids: An Update
    Aleksandra Kozłowska
    Nutrients.2025; 17(6): 956.     CrossRef
  • Sleep Disorders: Pathogenesis and Therapeutic Interventions
    Cheng Liu, Zhigang He, Yanqiong Wu, Yanbo Liu, Zhixiao Li, Yifan Jia, Hongbing Xiang
    MedComm.2025;[Epub]     CrossRef
  • Estimated sdLDL-C as a biomarker of hepatic steatosis severity in MASLD: a retrospective study
    Shuo Jiang, Fan Zhang, Hui Yang, Xue Han, Jieru Mao, Guojun Zheng, Yan Fan
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Fu brick tea supplementation ameliorates non-alcoholic fatty liver disease and associated endotoxemia via maintaining intestinal homeostasis and remodeling hepatic immune microenvironment
    Gaolong Zuo, Menghua Li, Xiaoli Guo, Ling Wang, Yanyan Yao, Jian-an Huang, Zhonghua Liu, Yong Lin
    Food Research International.2025; 209: 116207.     CrossRef
  • Association of occupational physical activity and sedentary behaviour with the risk of hepatocellular carcinoma: a case-control study based on the Inpatient Clinico-Occupational Database of Rosai Hospital Group
    Shoko Nakazawa, Kota Fukai, Kei Sano, Yuko Furuya, Keika Hoshi, Noriko Kojimahara, Akihiro Toyota, Masaaki Korenaga, Masayuki Tatemichi
    BMJ Open.2025; 15(3): e092020.     CrossRef
  • Metabolic diseases and interferon immune responses
    Haiyan Zhou, Chunyan Liu, Yuerong Zhang, Hui Zheng
    Interdisciplinary Medicine.2025;[Epub]     CrossRef
  • Impact of blood lead and manganese levels on metabolic dysfunction-associated steatotic liver disease prevalence: insights from NHANES (2017–2020)
    Wenying Guo, Ting Weng, Yufei Song
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • RNA Modification in Metabolism
    Yadi Liu, Zhongyan Sun, Dingkun Gui, Yonghua Zhao, Youhua Xu
    MedComm.2025;[Epub]     CrossRef
  • Does the hepatologist still need to rely on aminotransferases in clinical practice? A reappraisal of the role of a classic biomarker in the diagnosis and clinical management of chronic liver diseases
    Patrizia Burra, Calogero Cammà, Pietro Invernizzi, Fabio Marra, Maurizio Pompili
    Annals of Hepatology.2025; 30(1): 101900.     CrossRef
  • Omega-3 Fatty Acids, Furan Fatty Acids, and Hydroxy Fatty Acid Esters: Dietary Bioactive Lipids with Potential Benefits for MAFLD and Liver Health
    Camil Merheb, Sabine Gerbal-Chaloin, François Casas, Mona Diab-Assaf, Martine Daujat-Chavanieu, Christine Feillet-Coudray
    Nutrients.2025; 17(6): 1031.     CrossRef
  • Photon-counting CT–derived Quantification of Hepatic Fat Fraction: A Clinical Validation Study
    Tatjana Dell, Narine Mesropyan, Yannik Layer, Verena Tischler, Leonie Weinhold, Johannes Chang, Christian Jansen, Bernhard Schmidt, Markus Jürgens, Alexander Isaak, Patrick Kupczyk, Claus Christian Pieper, Carsten Meyer, Julian Luetkens, Daniel Kuetting
    Radiology.2025;[Epub]     CrossRef
  • Unravelling the Role of PANoptosis in Liver Diseases: Mechanisms and Therapeutic Implications
    Wanyuan Xiong, Junfeng Li, Aiping Tian, Xiaorong Mao
    Liver International.2025;[Epub]     CrossRef
  • Elevated red blood cell folate levels are associated with metabolic dysfunction-associated steatotic liver disease: results from NHANES 2017–2020
    Xin Liao, Song Yu, Lin Wang, Ruyue Zhang, Ke Yu
    Frontiers in Physiology.2025;[Epub]     CrossRef
  • Metrology for MRI: the field you’ve never heard of
    Matt G. Hall, Matt Cashmore, Hyo-Min Cho, Bernd Ittermann, Kathryn E. Keenan, Christoph Kolbitsch, Changwoo Lee, Chengwei Li, Asante Ntata, Katie Obee, Zhang Pu, Stephen E. Russek, Karl F. Stupic, Lukas Winter, Luca Zilberti, Michael Steckner
    Magnetic Resonance Materials in Physics, Biology and Medicine.2025; 38(3): 387.     CrossRef
  • Dual inhibition of hepatic ACLY and ACSS2: A synergistic approach to combat NAFLD through lipogenesis reduction and mitochondrial enhancement
    Mengdi Zhang, Jinliang Ji, Yuanyuan Lei, Fujian Qin, Yitong Tao, Ning Li, Jinlei Bian, Zhiyu Li, Maode Lai, Zhixia Qiu
    Pharmacological Research.2025; 215: 107706.     CrossRef
  • Akkermansia muciniphila ameliorates olanzapine-induced metabolic dysfunction-associated steatotic liver disease via PGRMC1/SIRT1/FOXO1 signaling pathway
    Hui Chen, Ting Cao, ChenQuan Lin, ShiMeng Jiao, YiFang He, ZhenYu Zhu, QiuJin Guo, RenRong Wu, HuaLin Cai, BiKui Zhang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • MASLD or MAFLD: fatty liver by any name will pose the same challenge
    Anil Chandra Anand, Dibyalochan Praharaj
    Metabolism and Target Organ Damage.2025;[Epub]     CrossRef
  • Hallmarks of Cancer Cachexia: Sexual Dimorphism in Related Pathways
    Setareh Satari, Inês N. R. Mota, Ana Carolina Leão Silva, Haissa Oliveira Brito, Paula A. Oliveira, Rui Miguel Gil da Costa, Rui Medeiros
    International Journal of Molecular Sciences.2025; 26(9): 3952.     CrossRef
  • Sex‐Specific Impact of Metabolic Dysfunction‐Associated Fatty Liver Disease on Incident Cardiovascular Diseases and Mortality
    Mahsa Abbaszadeh, Farhad Hosseinpanah, Maryam Tohidi, Sahar Karimpour Reyhan, Maryam Mahdavi, Majid Valizadeh
    Endocrinology, Diabetes & Metabolism.2025;[Epub]     CrossRef
  • Relationship of serum 25(OH)D3 and PTX3 with liver fat content in patients with non-alcoholic fatty liver disease: Diagnostic value for liver fibrosis
    Jian-Ji Dai, Yi Deng, Guo-Feng Wang, Kai-Qin Lin, Jian-Rong He, Xiao-Gang Hu
    World Chinese Journal of Digestology.2025; 33(3): 192.     CrossRef
  • Role of regulatory T cells in inflammatory liver diseases
    Linjie Yang, Song Guo Zheng
    Autoimmunity Reviews.2025; 24(6): 103806.     CrossRef
  • Cardiac Remodeling and Arrhythmic Burden in Pre-Transplant Cirrhotic Patients: Pathophysiological Mechanisms and Management Strategies
    Charilila-Loukia Ververeli, Yannis Dimitroglou, Stergios Soulaidopoulos, Evangelos Cholongitas, Constantina Aggeli, Konstantinos Tsioufis, Dimitris Tousoulis
    Biomedicines.2025; 13(4): 812.     CrossRef
  • Elevated miR-34a induced by lipotoxicity and inflammation mediates pathophysiological communication between hepatocytes and hepatic stellate cells in liver fibrosis
    Qihua Duan, Ruixiang Hu, Yan Chen, Henry Wade, Szczepan Kaluzny, Bingrui Zhang, Rongxue Wu, Guangnan Liu, Cunchuan Wang, Edward N. Harris, Qiaozhu Su
    Genes & Diseases.2025; 12(6): 101648.     CrossRef
  • Association of serum iron status with MASLD and liver fibrosis
    Wenying Guo, Ting Weng, Yufei Song, Anna Di Sessa
    PLOS ONE.2025; 20(4): e0319057.     CrossRef
  • Nephrological, Pulmonary, and Dermatological Complications in the Context of MAFLD/NAFLD: A Narrative Review
    Vlad Pădureanu, Dalia Dop, Lucrețiu Radu, Dumitru Rădulescu, Rodica Pădureanu, Denisa Floriana Vasilica Pîrșcoveanu, Daniel Cosmin Caragea
    Metabolites.2025; 15(4): 272.     CrossRef
  • Rhizoma Atractylodis Macrocephalae reduces HFD-induced NAFLD in mice through activated AMPK mediated inhibition of fatty acid synthesis
    Ke Zheng, RuiShuo Zhang, Yijing Xin, Yuge Zhou, Jiacheng Lin, Weifan Huang, Fang Wang, Liu Yang, Xuehua Sun, Xiaoni Kong
    Liver Research.2025;[Epub]     CrossRef
  • Increased Mechanical Index Improves Shear Wave Elastography: Pilot Study of Signal Enhancement
    Scott Schoen, Michael Wang, Sunethra Dayavansha, Kim Naja, Viksit Kumar, Rimon Tadross, Kathleen Pope, Lauren Ling, David Hunt, Mary K. Peters, Ann Iafrate, Nathaniel D. Mercaldo, Kurt Sandstrom, TaeYun Kim, Mike Washburn, Theodore T. Pierce, Anthony E. S
    Ultrasound in Medicine & Biology.2025; 51(7): 1070.     CrossRef
  • A Systematic Review of the Beneficial Effects of Berry Extracts on Non-Alcoholic Fatty Liver Disease in Animal Models
    Alejandro García-Beltrán, Aida Lozano Melero, Rosario Martínez Martínez, Jesús María Porres Foulquie, María López Jurado Romero de la Cruz, Garyfallia Kapravelou
    Nutrition Reviews.2025; 83(5): 819.     CrossRef
  • Linghe granules reduces hepatic lipid accumulation in Non-alcoholic fatty liver disease through regulating lipid metabolism and redox balance
    Yuting Hu, Ni'ao Li, Rumian Zhang, Jia Wang, Dongdong Fang, Qianmei Zhou, Hua Zhang, Hong Cai, Yiyu Lu
    Phytomedicine.2025; 141: 156654.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease (MASLD): Exploring systemic impacts and innovative therapies
    Parag Jain, Akanksha Jain, Rohitas Deshmukh, Pradeep Samal, Trilochan Satapathy, Ajazuddin
    Clinics and Research in Hepatology and Gastroenterology.2025; 49(6): 102584.     CrossRef
  • Luteolin Relieves Metabolic Dysfunction-Associated Fatty Liver Disease Caused by a High-Fat Diet in Rats Through Modulating the AdipoR1/AMPK/PPARγ Signaling Pathway
    Pongsakorn Taweesap, Prapassorn Potue, Juthamas Khamseekaew, Metee Iampanichakul, Banyaphon Jan-O, Poungrat Pakdeechote, Putcharawipa Maneesai
    International Journal of Molecular Sciences.2025; 26(8): 3804.     CrossRef
  • Association between non-skimmed milk consumption and metabolic dysfunction-associated fatty liver disease in US adults: insights from NHANES data
    Futao Wu, Fuying Zheng, Xue Li, Danzhu Wu, Honghao Li, Yingyi Zeng, Yan Tang, Side Liu, Aimin Li
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Discovery of the first-in-class FABP/PPAR multiple modulator for the treatment of metabolic dysfunction-associated steatohepatitis
    Ya Chen, Zibin Liao, Jianming Mao, Wenxin Wang, Yuxia Liu, Wei Dai, Zheng Wen, Sishi Liu, Yayi Chen, Yiming Ma, Xiaoying Wang, Zheng Li
    European Journal of Medicinal Chemistry.2025; 291: 117635.     CrossRef
  • Astragaloside IV as a promising therapeutic agent for liver diseases: current landscape and future perspectives
    Chunyan Chen, Xiaolan Bu, Liping Deng, Jiayan Xia, Xinming Wang, Li Chen, Wen Li, Jie Huang, Qixiang Chen, Cheng Wang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Targeting Metabolism: Innovative Therapies for MASLD Unveiled
    Weixin Wang, Xin Gao, Wentong Niu, Jinping Yin, Kan He
    International Journal of Molecular Sciences.2025; 26(9): 4077.     CrossRef
  • Unsupervised Test-Time Adaptation for Hepatic Steatosis Grading Using Ultrasound B-Mode Images
    Pedro Vianna, Paria Mehrbod, Muawiz Chaudhary, Michael Eickenberg, Guy Wolf, Eugene Belilovsky, An Tang, Guy Cloutier
    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.2025; 72(5): 601.     CrossRef
  • Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry and Network Pharmacology Reveal the Mechanisms of Rhodiola crenulata in Improving Non-Alcoholic Fatty Liver Disease
    Xin Zeng, Jianwei Wang, Qinyi Xu, Chengdan Deng, Xi Yi, Shang Wang, Ling Yao, Wei Xiang
    Current Issues in Molecular Biology.2025; 47(5): 324.     CrossRef
  • Abnormalities of intracellular organelles in metabolic dysfunction-associated steatotic disease
    Hidenori Kido, Eishiro Mizukoshi, Masahiro Yanagi, Li Shihui, Takuya Seike, Hidetoshi Nakagawa, Tetsumori Yamashima, Yoshitake Shiraishi, Noriyuki Ozaki, Kenichi Harada, Hikari Okada, Hisanori Goto, Kumi Kimura, Yasuhiko Yamamoto, Taro Yamashita
    Journal of Gastroenterology.2025; 60(8): 990.     CrossRef
  • Modulation of liver lipid metabolic pathways by central nervous system ER stress
    Han Rae Kim, Parisa Tabiatnejad, Hovhannes Arestakesyan, Colin N. Young
    American Journal of Physiology-Endocrinology and Metabolism.2025; 328(6): E833.     CrossRef
  • Unraveling the Metabolic Pathways Between Metabolic-Associated Fatty Liver Disease (MAFLD) and Sarcopenia
    Marina Ribas Losasso, Maria Luiza Cesto Parussolo, Antony Oliveira Silva, Rosa Direito, Karina Quesada, Claudia Rucco Penteado Detregiachi, Marcelo Dib Bechara, Nahum Méndez-Sánchez, Ludovico Abenavoli, Adriano Cressoni Araújo, Ricardo de Alvares Goulart,
    International Journal of Molecular Sciences.2025; 26(10): 4673.     CrossRef
  • Unveiling the role of IL7R in metabolism-associated fatty liver disease leading to hepatocellular carcinoma through transcriptomic and machine learning approaches
    Priyadharshini Annadurai, Arnold Emerson Isaac
    Discover Oncology.2025;[Epub]     CrossRef
  • Managing Nonalcoholic Fatty Liver Disease Through Structured Lifestyle Modification Interventions
    Andrew Thomas, Annie Thomas
    American Journal of Lifestyle Medicine.2025;[Epub]     CrossRef
  • Draft Clinical Guidelines for the Diagnosis and Treatment of Metabolically Associated Fatty Liver Disease in Children (Non-Alcoholic Fatty Liver Disease)
    Alexander A. Baranov, Galina V. Volynets, Nikolay N. Vlasov, Larisa G. Goryacheva, Margarita M. Gurova, Vera A. Greshnyakova, Anna N. Zaviyalova, Nina V. Evdokimova, Marina Yu. Komissarova, Leyla S. Namazova-Baranova, Valeriya P. Novikova, Elena V. Pavlov
    Pediatric pharmacology.2025; 22(2): 147.     CrossRef
  • Association between organochlorine pesticides and metabolic dysfunction-associated steatotic liver disease: Findings from the Dongfeng-Tongji cohort
    Yi Guo, Xin Guan, Yutong You, Chengyong Jia, Yuhui Lin, Zhen Yin, Yu Yin, Guorong Zhong, Yuying Wen, Wenhui Li, Hui Zhao, Shengli Chen, Xi Wang, Xinlian Li, Xuanwen Mu, Pinpin Long, Hao Wang, Xiaomin Zhang, Meian He, Yu Yuan, Tao Jing, Huan Guo, Tangchun
    Environment International.2025; 201: 109571.     CrossRef
  • Intestinal L-cell mechanoreception regulates hepatic lipid metabolism through GLP-1
    Luyang Gao, Ke Yang, Yawen Zhao, Jinshan Zhang, Shaohua Jiang, Rujiao Zhang, Wenxin He, Yuhang Zhao, Qianqian Ye, Geyang Xu
    Science Advances.2025;[Epub]     CrossRef
  • KRT23 as a Potential Target for Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): Evidence From Bioinformatics Analysis, Human Gene Polymorphism and Animal Experiments
    Yangmin Hao, Tao Zhang, Shaliyan Tuerxunmaimaiti, Ye Tian, Xinyu Wang, Zhiming Li, Liang Zhao, Lei Bai, Qu Chen, Cheng Li, Ayiguzhali Abulitipu, Rui Wang, Sheng Jiang, Guoli Du
    International Journal of General Medicine.2025; Volume 18: 2807.     CrossRef
  • Evolving Public Attention to Steatotic Liver Disease: A 20‐Year Analysis (2004–2024)
    Pojsakorn Danpanichkul, Charat Thongprayoon, Kanokphong Suparan, Donghee Kim, Ornpailin Wanichthanaolan, Phuuwadith Wattanachayakul, Yanfang Pang, Mark D. Muthiah, Anand V. Kulkarni, Ju Dong Yang, Apichat Kaewdech, Wisit Cheungpasitporn, Karn Wijarnpreech
    Journal of Gastroenterology and Hepatology.2025; 40(8): 2053.     CrossRef
  • ECM formation and degradation during fibrosis, repair, and regeneration
    Alejandro E. Mayorca-Guiliani, Diana Julie Leeming, Kim Henriksen, Joachim Høg Mortensen, Signe Holm Nielsen, Quentin M. Anstee, Arun J. Sanyal, Morten A. Karsdal, Detlef Schuppan
    npj Metabolic Health and Disease.2025;[Epub]     CrossRef
  • The role of SIRT2 in homeostatic medicine and aging intervention
    Yue Li, Longchuan Han, Yinkun Fu, Yingting Zhang, Zhihui Zou, Jing Luo, Xinxin Tang, Lihong Tian, Yuheng Lu, Ying Huang, Ming He
    Oral Science and Homeostatic Medicine.2025; 1(1): 9610009.     CrossRef
  • Integration of Metabolomics, Lipidomics, and Machine Learning for Developing a Biomarker Panel to Distinguish the Severity of Metabolic‐Associated Fatty Liver Disease
    Yanqiao Hui, Jiameng Qu, Junjie Yang, Hanwen Zhang, Chen Liang, Naixin Miao, Qian Zhang, Huarong Xu, Yiling Li, Qing Li
    Biomedical Chromatography.2025;[Epub]     CrossRef
  • Prevalence and predictors of non‐alcoholic fatty liver disease (NAFLD) and metabolic dysfunction‐associated fatty liver disease (MAFLD) in Indian women with polycystic ovarian syndrome
    Aditi Rathi, Deepti Goswami, Anju Garg, Smita Kaushik, Niharika Dhiman
    Journal of Obstetrics and Gynaecology Research.2025;[Epub]     CrossRef
  • The role of plasma glucose in association of food-specific serum immunoglobulin G reactivity with metabolic dysfunction-associated fatty liver disease: a real-world cross-sectional study
    Guanchao Sun, Wenjuan Wu, Binbin Su, Ru Zhang, Xiaoyu Dong, Lihui Wang, Shiping Xu, Hui Shi
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • Medical Implications of Renaming Non-Alcoholic Fatty Liver Disease (NAFLD) to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
    Yu-Jin Choi, Chang-Gue Son
    Journal of Korean Medicine.2025; 46(2): 40.     CrossRef
  • Serum uric acid/creatinine ratio and metabolic-associated fatty liver disease risks in children
    Bi Chen, Xiaoning Qu, Ting Li, Minghua Jiang
    Pediatric Research.2025;[Epub]     CrossRef
  • The FMO3/TMAO/HSP90β axis aggravates MAFLD by disrupting mitochondrial protein homeostasis
    Jin Guo, Yukun Wang, Danmei Zhang, Chunxia Shi, Xiaoya Zhang, Xun Li, Zuojiong Gong
    Cellular Signalling.2025; 134: 111960.     CrossRef
  • Anti-steatotic effect of Opuntia ficus-indica extracts rich in betalains and phenolics from fruit peel and pulp of different varieties in in vitro models
    Irene Besné-Eseverri, Jenifer Trepiana, Itziar Eseberri, Andrea Gómez-Maqueo, M. Pilar Cano, Joao Tomé-Carneiro, Alberto Dávalos, María P. Portillo
    Journal of Physiology and Biochemistry.2025; 81(4): 1305.     CrossRef
  • Regulatory Mechanisms of Phenolic Acids in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review
    Shengyu Zhang, Congcong Shen, Han Di, Yanhong Wang, Feng Guan
    Antioxidants.2025; 14(7): 760.     CrossRef
  • Fatty liver index and risk of type 2 diabetes of adults with normoglycemia: Insights into insulin sensitivity and beta-cell function
    Ji Hyun Bae, Min Jin Lee, Su Hyun Kim, Joo Yeon Kim, Ah Reum Khang, Yang Ho Kang, Dongwon Yi, Guoying Wang
    PLOS One.2025; 20(6): e0327058.     CrossRef
  • Lessons Learned from Liver-on-Chip Platform
    Zahra Sadat Razavi, Fateme Sadat Razavi, Madjid Soltani, Hamidreza Pazoki-Toroudi, Simin Farokhi, Iraj Azimi, Nahid Ahmadi
    Annals of Biomedical Engineering.2025; 53(9): 1993.     CrossRef
  • Loss of endothelial ZEB2 in mice attenuates steatosis early during metabolic dysfunction-associated steatotic liver disease
    Wouter Dheedene, Stefaan Verhulst, Louise Demuynck, Bram Callewaert, Willeke de Haan, Stefan Vinckier, Jore Van Wauwe, Petra Vandervoort, Marleen Lox, Mathias Stroobants, Renaud Lavend’homme, Wilfred F. J. van IJcken, Elizabeth A. V. Jones, An Zwijsen, Ma
    Scientific Reports.2025;[Epub]     CrossRef
  • Prevalence of advanced liver fibrosis in the general population of the Paris region according to FIB-4 score and liver risk score
    Henri Tran, Stefano Caruso, Anne-Laure Mazialivoua, Cecile Fargeat, Odile Rousselet, Adrien Ko, Vincent Leroy, Patrick Ingiliz
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • TyG-BMI as a superior predictor of MAFLD and pre-MAFLD in Chinese adults: a cross-sectional study
    Xinru Huang, Yanyun Hu, Lining Dong, Liying Zhu, Jie Li, Ji Hu, Wei Shao, Yongde Peng, Fang Liu
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Immune Microenvironment on the Molecular Mechanisms and Therapeutic Targets of MAFLD
    Zhonghao Jiang, Baolin Qian, Tongjie Xu, Junjie Bai, Wenguang Fu
    ImmunoTargets and Therapy.2025; Volume 14: 719.     CrossRef
  • The expanding role of semaglutide: beyond glycemic control
    Malek Zarei, Masoumeh Sabetkasaei, Masoud Mozafari, Sasan Zaeri
    Journal of Diabetes & Metabolic Disorders.2025;[Epub]     CrossRef
  • Quantitative characterization of drug metabolism and transport alterations in obesity with metabolic fatty liver disease: A physiologically based pharmacokinetic modelling approach
    Yuewu Xie, Xiaoqin Bai, Chaozhuang Shen, Chaoran Xu, Chi Cui, Yujie Yang
    Journal of Pharmaceutical Sciences.2025; 114(9): 103906.     CrossRef
  • Prevalencia e importancia de la enfermedad periodontal en pacientes con enfermedad hepática esteatósica asociada a disfunción metabólica (MASLD) en Veracruz
    L. Roesch-Ramos, D.N. Guzmán-Uzcanga, S. Nolasco-Polito, S. Pérez-Pérez, F. Moreno-Marín, R.M. Francisco, H.R. Ordaz-Álvarez, F.B. Roesch-Dietlen, J.M. Remes-Troche, A.D. Cano-Contreras
    Revista de Gastroenterología de México.2025;[Epub]     CrossRef
  • Recent advances in the treatment of non-alcoholic fatty liver disease with astragaloside IV
    Hui Wang, Yunqin Jiang, Shiyun Wang, Chanchan Lu, Lumin Tang, Tingting Gu, Shi Shu
    Acta Pharmaceutica.2025; 75(3): 309.     CrossRef
  • Differential effects of sleep duration on cardiovascular risk in metabolic-associated fatty liver disease vs. without metabolic-associated fatty liver disease: evidence from National Health and Nutrition Examination Survey and Mendelian randomization
    Siyao Wang, Xinyi Liu, Jia He, Yihan Cui, Ai Jia
    European Journal of Gastroenterology & Hepatology.2025; 37(12): 1380.     CrossRef
  • Lipid Hormones at the Intersection of Metabolic Imbalances and Endocrine Disorders
    Maria-Zinaida Dobre, Bogdana Virgolici, Ruxandra Cioarcă-Nedelcu
    Current Issues in Molecular Biology.2025; 47(7): 565.     CrossRef
  • Shift in the urinary metabolome associated with 2,3,7,8-tetrachlorodibenzo-p-dioxin activation of the hepatic aryl hydrocarbon receptor
    Warren J. Sink, Russell Fling, Ali Yilmaz, Rance Nault, Delanie Goniwiecha, Jack R. Harkema, Stewart F. Graham, Tim Zacharewski
    Scientific Reports.2025;[Epub]     CrossRef
  • Serum metabolites and gut microbiota mediate the causal link between anxiety and nonalcoholic fatty liver disease: a Mendelian randomization analysis
    Siyao Wang, Xinyi Liu, Jia He, Yihan Cui, Ai Jia
    European Journal of Gastroenterology & Hepatology.2025; 37(12): 1370.     CrossRef
  • Gut microbiota as a metabolic mediator to prevent or attenuate MASLD
    Jing Luo, Yijiang Wei, Zhexin Fan, Baokun Li, Lingzhi Li, Yiwei Chai, Zihan Xing, Yingying Qiu, Wenwei Lu, Zhifeng Fang
    Critical Reviews in Food Science and Nutrition.2025; : 1.     CrossRef
  • Applications of artificial intelligence in liver cancer: A scoping review
    Andrea Chierici, Fabien Lareyre, Antonio Iannelli, Benjamin Salucki, Sébastien Goffart, Lisa Guzzi, Elise Poggi, Hervé Delingette, Juliette Raffort
    Artificial Intelligence in Medicine.2025; 169: 103244.     CrossRef
  • Soybean genistin-driven gut microbiota-derived butyrate synthesis activates the SIRT1 signaling pathway to ameliorate metabolic fatty liver
    Guohui Yi, Wanying Sun, Xueer Zhang, Zhongtao Wang, Xiaodan Yu, Canyang Zhu, Kaiwen Lin
    Free Radical Biology and Medicine.2025; 239: 336.     CrossRef
  • Relación entre el control de la psoriasis y la enfermedad hepática esteatósica asociada a disfunción metabólica
    Citlalli Guadalupe Hernández Guzmán, Blanca Elena Verazaluce Rodríguez, Lauro Fabián Amador Medina, Graciela López Mata, Erick Josefat Díaz Huerta, Óscar Noel Chávez Hernández
    Piel.2025; 40(9): 558.     CrossRef
  • MASLD vs. MAFLD. A narrative review
    Amedeo Lonardo, Ming-Hua Zheng, Mohammed Eslam
    Exploration of Digestive Diseases.2025;[Epub]     CrossRef
  • Sweroside: unveiling broad therapeutic potential—from mechanistic insights to clinical potential
    Liu Peng, Man Zuo, Tian Qiu, Wenying Lan, Yue Wen, Xiao-Qin Ye
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Mechanisms and Therapeutic Advances of PXR in Metabolic Diseases and Cancer
    Yuanbo Bi, Sifan Liu, Lei Wang, Daiyin Peng, Weidong Chen, Yue Zhang, Yanyan Wang
    International Journal of Molecular Sciences.2025; 26(16): 8029.     CrossRef
  • Understanding MASLD — from molecular pathogenesis to cardiovascular risk: A concise review for the clinical cardiologist
    Carlo Ratti, Mattia Malaguti, D'Aniello Emanuele, Antonio Bellasi, Gianluca Sanna
    Atherosclerosis.2025; 409: 120495.     CrossRef
  • Global burden of NAFLD 1990–2021 and projections to 2035: Results from the Global Burden of Disease study 2021
    Yuqin Mao, Jiqing Du, Baoguo Li, Jiong Wang, Shaoyan Xuan, Shu Yang, Zhihua Tang, Minxiu Wang, Hamidreza Karimi-Sari,
    PLOS One.2025; 20(8): e0330504.     CrossRef
  • Impact of Liraglutide 3.0 mg on Metabolic Dysfunction-Associated Steatotic Liver Disease in Individuals with Obesity: A Real-World Study
    Jungha Park, Jin-Wook Kim, Soo Lim
    Annals of Nutrition and Metabolism.2025; : 1.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease as a Risk Factor for Chronic Kidney Disease: A Narrative Review
    Marcelo do Rego Maciel Souto Maior, Nathália de Lacerda Interaminense Ribeiro, Hannah Vicentini Vitoriano Silva, Edmundo Pessoa Lopes, Emilia Chagas Costa
    Biomedicines.2025; 13(9): 2162.     CrossRef
  • Association of Daily Steps with Incident Nonalcoholic Fatty Liver Disease: Evidence from the UK Biobank Cohort
    EVELYNNE S. FULDA, LAURA PORTAS, CHARLIE HARPER, DAVID PREISS, DERRICK BENNETT, AIDEN DOHERTY
    Medicine & Science in Sports & Exercise.2025; 57(9): 1905.     CrossRef
  • Performance Assessment of ChatGPT-4.0 and ChatGLM Series in Traditional Chinese Medicine for Metabolic Associated Fatty Liver Disease: Comparative Study
    Xionghui Wang, Tianxiao Zheng, Bo Liu, Zhi Pei, Kaihan Meng, Changquan Ling
    JMIR Formative Research.2025; 9: e66503.     CrossRef
  • Circulating ORM2 as a Biomarker of Metabolic Dysfunction: Evidence from the KADEM Study in Kuwaiti Adults
    Mohamed Abu-Farha, Ahmed N. Albatineh, Bader Alawadh, Loulwa Alsalem, Irina Al-Khairi, Preethi Cherian, Fahad Al-Ajmi, Mohammad Qaddoumi, Muhammad Abdul-Ghani, Fahd Al-Mulla, Jehad Abubaker
    International Journal of Molecular Sciences.2025; 26(17): 8326.     CrossRef
  • Hic-5 deficiency attenuates MAFLD by inhibiting neutrophils migration via the CXCL1-CXCR2 axis
    Bingyu Ren, Han Li, Shenglu Liu, Zhiwei Huang, Junjie Bai, Zhonghao Jiang, Tongjie Xu, Boyuan Gu, Wenhao Yu, Lei Sun, Peng Tan, Wenguang Fu
    Journal of Gastroenterology.2025; 60(12): 1535.     CrossRef
  • Association of exposure to phenols, pesticides, and phthalates with hepatic steatosis and MASLD in adolescents: the potential role of inflammation and lifestyle factors
    Xiaodie Yao, Cai Tang, Yu Li, Congwei You, Haoyang Zhang, Xiaohong Gu, Kerong Liu, Le Zhang
    Metabolism and Target Organ Damage.2025;[Epub]     CrossRef
  • A synergic GLP-1/Acylethanolamide-based combined therapy for MAFLD: Studies in rat models
    Marialuisa de Ceglia, Rubén Tovar, Miguel Rodríguez-Pozo, Antonio Vargas, Ana Gavito, Juan Suárez, Elena Baixeras, Fernando Rodríguez de Fonseca, Juan Decara
    Biochemical Pharmacology.2025; 242: 117364.     CrossRef
  • Association of elevated Alpha-1-Acid glycoprotein with MAFLD prevalence in young and middle-aged women: a cross-sectional study based on NHANES 2017–2020
    Yi Xiao, Xian Luo, Yinghao Fu, Haijuan Huang, Qiaoping Gao, Jiansong Liu, Daxin Pang, Xiaolu Liang, Huadi Chen, Hao Xu
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • Development of a nomogram model for predicting coronary heart disease in patients with metabolic-associated fatty liver disease
    Zhengliang Li, Xiaokai Chen, Juan Wang, Weirui Chen, Run Zhang, Lihua Cao, Shaoting Shi, Linlin Ren, Wenzhong Zhang
    Frontiers in Cardiovascular Medicine.2025;[Epub]     CrossRef
  • In Silico Study of Natural Polyphenols as Potential Metabolic Modulators in Mitigating Lipotoxicity in Non-Alcoholic Fatty Liver Disease via Thyroid Hormone Receptor Alpha Activation
    Evangelia K. Konstantinou, Athanasios A. Panagiotopoulos, Maria Dimitriou
    Current Issues in Molecular Biology.2025; 47(9): 777.     CrossRef
  • A Comprehensive Systematic Review on Therapeutic Discovery of NAFLD Drugs
    Sajja Keerthi Vathsalya, A. Gnanavel, N. Hima Bindu, S. Saravana Kumar, B. Naveen Kumar
    Research Journal of Pharmacy and Technology.2025; : 4564.     CrossRef
  • Sugar-sweetened beverage consumption predicts metabolic associated fatty liver disease in patients with type 2 diabetes mellitus
    Zhenjun Yu, Mengdie Chen, Shicheng Gu, Chaohui Wang, Ping Feng, Gang Lin
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Analysis of the Association Between TG/HDL, TyG, TyG-BMI, and ZJU Indices with Metabolic Dysfunction-Associated Fatty Liver Disease in Patients with Type 2 Diabetes
    Yunyi Yang, Hongping Wang, Yanming He, Xiaoli He, Zheng Yao, Hongjie Yang
    Diabetes, Metabolic Syndrome and Obesity.2025; Volume 18: 3797.     CrossRef
  • Analysis of subgingival microbial community structure in MAFLD patients with periodontitis
    Hai He, Jingli Zhu, Chuyi Li, Qisheng Shen, Jiarui Cao, Jinhai Ma, Zhenghu Feng, Zhiqiang Li, Tianzhu Song
    Clinical Oral Investigations.2025;[Epub]     CrossRef
  • Combined effect of metformin and ezetimibe on PPAR-γ and adiponectin gene expression and biochemical parameters in MAFLD patients with type 2 diabetes
    Asiyeh Masaeli, Mohammad Taghi Goodarzi, Adel Mohammadalipour, Safa Ali-Asgari, Mohammad Reza Mirzaei, Mohsen Hani
    Scientific Reports.2025;[Epub]     CrossRef
  • Nonlinear association between TyG-BMI and MAFLD: A cross-sectional study
    Qiuping Wang, Yuan Su, Jing Niu, Yan Wang, Liping Liu, Yanhong Hao, Qian Wu
    PLOS One.2025; 20(10): e0331140.     CrossRef
  • Polycystic ovarian syndrome a risk factor for non-communicable diseases: insights into recent research and prevention approaches
    Iqra Naeem, Ayman Zehra, Faiza Rehman, Abid Hussain, Azhar Hussain, Nisar Hussain, Muhammad Waseem, Reem Mohammed Alqahtani, Ghalia Shamlan, Isam A. Mohamed Ahmed, Muhammad Faisal Manzoor, Muhammed Adem Abdullahi
    Journal of Ovarian Research.2025;[Epub]     CrossRef
  • The transition from NAFLD to MASLD: implications for Diagnosis, Prognosis, and Clinical Management
    Carlo Acierno, Riccardo Nevola, Fannia Barletta, Katarzyna Zielińska, Luca Rinaldi, Ferdinando Carlo Sasso, Caterina Conte, Luigi Elio Adinolfi, Alfredo Caturano
    Exploration of Medicine.2025;[Epub]     CrossRef
  • Research trends on the quality of life in patients with metabolic dysfunction-associated fatty liver diseases: a scientific metrology study
    Can Huang, Meng Chen, Yanfang Sun, Lin Zhang, Wei Liu
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Perilipins: key targets for regulating lipid metabolism and alleviating abnormal lipid metabolism through exercise
    Yan-Jun Niu, Jing-Jing Liu, Jing-Hua Zhang, Shi-Qi Lu, Ke Wang, Zheng Zhu, Zhen-Bo Cao
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • CircRNA in Digestive Diseases: Recent Advances in Fundamental Mechanism and Clinical Potential
    Yuanye Ji, Shun Zhang, Ting Cai, Liyun Fu, Qinzhi Deng, Peng Zhu
    Current Molecular Medicine.2025; 25(9): 1107.     CrossRef
  • Plasma and fecal bile acids profiles in metabolic dysfunction-associated steatotic liver disease with advanced fibrosis
    Marion Pradeau, Sandrine Beaulieu, Véronique Paquet, Jocelyn Trottier, Mélanie Verreault, Stéphanie Ferland, Olivier Barbier, Anne-Marie Carreau
    American Journal of Physiology-Endocrinology and Metabolism.2025; 329(5): E644.     CrossRef
  • Analysis of risk factors associated with metabolic-associated fatty liver disease from Suzhong Region, China: a cross-sectional study
    Shuai Zhang, Hao Liang, Jun Liu, Ye Zhu
    BMJ Open.2025; 15(10): e096598.     CrossRef
  • Predicting Metabolic Dysfunction–Associated Fatty Liver Disease Phenotypes Among Adults: 2-Stage Contrastive Learning Method
    Sizhe Jasmine Chen, Da Xu, Derek K Hu, Paul Jen-Hwa Hu, Ting-Shuo Huang
    JMIR Medical Informatics.2025; 13: e75747.     CrossRef
  • Explainable machine learning model for classifying atherosclerotic cardiovascular disease in patients with metabolic dysfunction-associated steatotic liver disease
    Zhengliang Li, Xiaokai Chen, Linlin Ren, Banghui Wang, Shimiao Ruan, Juan Wang, Wenzhong Zhang
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • PGC-1α regulates lipid accumulation by coordinating fatty acid synthesis and oxidation in goose fatty liver
    Jiahui Li, Mengqing Lv, Long Liu, Tuoyu Geng, Daoqing Gong, Minmeng Zhao
    Poultry Science.2025; 104(12): 106052.     CrossRef
  • Association of vitamin D levels with metabolic dysfunction-associated fatty liver disease in children aged 12–18 years
    Xuejie Gao, Yuyun Chen, Xinrui Wang, Yuehang Chen, Xiaoyan Chen, Haibo Li, Hong Ye
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Bifidobacterium bifidum enhances hepatic mitochondrial β-oxidation and ameliorates MAFLD in a high-fat diet rat model
    Fatemeh Dashti, Ava Bolandparvaz, Anahita Panji, Zahra Hojatifar, Mahdi Alinejad, Mahtab Mehboodi, Mohammad Hassan Maleki, Afsaneh Mirshekari, Elham Nadimi
    Scientific Reports.2025;[Epub]     CrossRef
  • Betulinic acid as a novel AT1R inhibitor: attenuation of liver fibrosis via modulation of endothelial–mesenchymal transition in chronic hepatic injury
    Bingwen Zhu, Xiyu Dai, Chunyan Liu, Tao Bi, Shenglu Liu, Lei Chen, Ting Wang, Qixin Zhao, Xinyue Liu, Qin Sun, Yingcheng Yang, Zengjin Liu
    Journal of Translational Medicine.2025;[Epub]     CrossRef
  • Qushi Huayu decoction alleviates NAFLD in mice by regulating gut microbiota homeostasis in the gut-liver axis via the pregnane X receptor
    Yuan Xu, Yiming Ni, Mingmei Zhou, Xiaojun Gou
    European Journal of Pharmacology.2025; 1008: 178366.     CrossRef
  • Serum Extracellular Vesicles as Pathogenetic Signals in Obese and Lean Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease
    Chi-Yi Chen, Che-Yu Hsu, Wei-Pang Chung, Hung-Yu Sun, Tzu-Ching Kao, Tzu-Yi Chen, Xing-Min Li, Wei-Lung Huang, Kung-Chia Young
    Metabolites.2025; 15(11): 746.     CrossRef
  • Harnessing serum VOCs and machine learning for the early detection of MAFLD
    Xin Li, Xiaoyue Zhao, Ruonan Zhang, Xuewei Zhuang
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Diabetes mellitus and liver: Non-obvious aspects
    A. O. Bueverov, E. L. Bueverova
    FOCUS. Endocrinology.2025; 6(3): 41.     CrossRef
  • The role of hepatic steatosis Index, fatty liver Index, and metabolic and hormonal biomarkers in differentiating MASLD in polycystic ovary syndrome
    Enes Ucgul, Burak Menekse, Huseyin Demirci, Erman Cakal
    Journal of Endocrinological Investigation.2025;[Epub]     CrossRef
  • К эпидемиологии жировой болезни печени, связанной с метаболической дисфункцией (систематический обзор литературы)
    Вера Людвиговна Грицинская, Валерия Павловна Новикова
    Children's medicine of the North-West.2025; 13(3): 108.     CrossRef
  • Associations between composite systemic inflammation indicators(CAR, CLR, SII, AISI, SIRI, and CALLY) and metabolic dysfunction-associated fatty liver disease (MAFLD): evidence from a two-stage study in China
    Jing Zhao, Quan Zhou, Yun Wang, Fangfei Xie, Jingyi Fan
    Frontiers in Immunology.2025;[Epub]     CrossRef
  • Betaine Attenuates High‐Fat‐Diet‐Induced Metabolism‐Associated Steatotic Liver Disease via the Inhibition of Ferroptosis Through the Nrf2/GPX4 Axis
    Xiao‐jun Zhai, Cheng Xiao, Chun‐ru Yang, Ze‐rui Ding, Dong‐mei Wang, Jie‐ying Liu, Yu Miao
    The FASEB Journal.2025;[Epub]     CrossRef
  • Regulatory Role of Nuclear Factor of Activated T Cells c4 in the Development of Metabolic dysfunction-associated Fatty Liver Disease
    Tong Shen, Jia Chen, Luyao Li, Guohao Li, Qianyu Guo, Meie Liang, Quanhai Pang
    Current Atherosclerosis Reports.2025;[Epub]     CrossRef
  • Leucine Alleviates Endoplasmic Reticulum–Stress Mediated Lipotoxic Injury Induced by High-Fat Diet Via Sar1b/Sestrin2/Ampkα1 Pathways in Acanthopagrus Schlegelii
    Wenli Zhao, Yuedong Shen, Xuan Wang, Yangguang Bao, Óscar Monroig, Tingting Zhu, Xie Shichao, Peng Sun, Douglas R Tocher, Qicun Zhou, Min Jin
    The Journal of Nutrition.2025; : 101258.     CrossRef
  • MAFLD in Vietnam: a neglected public health challenge requiring urgent policy action
    Thong Duy Vo, Huong Tu Lam
    Frontiers in Clinical Diabetes and Healthcare.2025;[Epub]     CrossRef
  • Lactobacillus gasseri TF08-1 ameliorates high-fat diet induced nonalcoholic fatty liver disease and regulates gut microbiota in mice
    Qianyue Xu, Ningning He, Yu Tian, Zhinan Wu, Haoyu Wang, Bei Liu, Zizhen Yang, Haifeng Zhang, Qiang Luo, Yiyi Zhong, Liang Xiao, Shangyong Li, Yuanqiang Zou
    Journal of Applied Microbiology.2025;[Epub]     CrossRef
  • Traditional Chinese medicine for non-alcoholic fatty liver disease: an overview of systematic reviews with evidence mapping and metabolic outcome assessment
    Juanjuan Li, Ruimin Jiao, Wenquan Su, Wei Chen, Xiangyu Hu, Shuai Xu, Lie Xu, Weiwei Yao, Kejia Liu, Hong You, Jingjie Zhao
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Impact of Polyphenol Supplementation on Energy Expenditure Measured by Indirect Calorimetry in Adolescents with Metabolic Dysfunction-Associated Steatotic Liver Disease: A Pilot Randomized Study
    Christine Haïkal, Marie-Catherine Turcotte, Véronique Bélanger, Sophia Morel, Anik Cloutier, Emile Levy, Valérie Marcil, Ramy El-Jalbout, Véronique Groleau
    Healthcare.2025; 13(24): 3215.     CrossRef
  • Research Progress on the Role and Mechanism of Flavonoids in Improving Metabolic Associated Fatty Liver Disease
    Lala Qin, Qingsong Xiao, Xin Deng
    Diabetes, Metabolic Syndrome and Obesity.2025; Volume 18: 4597.     CrossRef
  • STEATOTIC LIVER DISEASE: THE IMPACT OF TEA AND COFFEE CONSUMPTION. LITERATURE REVIEW
    V.S. Rakhmetova
    Наука и здравоохранение.2025; (5(27)): 261.     CrossRef
  • Pre-MASLD: Should it be defined separately?
    Hang-Kai Huang, You-Ming Li, Cheng-Fu Xu
    Hepatobiliary & Pancreatic Diseases International.2024; 23(1): 1.     CrossRef
  • Object detection: A novel AI technology for the diagnosis of hepatocyte ballooning
    Tian‐Lei Zheng, Jun‐Cheng Sha, Qian Deng, Shi Geng, Shu‐Yuan Xiao, Wen‐Jun Yang, Christopher D. Byrne, Giovanni Targher, Yang‐Yang Li, Xiang‐Xue Wang, Di Wu, Ming‐Hua Zheng
    Liver International.2024; 44(2): 330.     CrossRef
  • Steatotic liver disease, MASLD and risk of chronic kidney disease
    Josh Bilson, Alessandro Mantovani, Christopher D. Byrne, Giovanni Targher
    Diabetes & Metabolism.2024; 50(1): 101506.     CrossRef
  • Role of autophagy in betaine-promoted hepatoprotection against non-alcoholic fatty liver disease in mice
    Jinuk Seo, Doyoung Kwon, Sou Hyun Kim, Mi Ran Byun, Yun-Hee Lee, Young-Suk Jung
    Current Research in Food Science.2024; 8: 100663.     CrossRef
  • Taohe Chengqi decoction alleviated metabolic-associated fatty liver disease by boosting branched chain amino acids catabolism in the skeletal muscles of type 2 diabetes mellitus
    Ziqiao Yuan, Hui Qiao, Ziwei Wang, Haoran Wang, Mingru Han, Wenzhou Zhang, Yang Zhou, Hozeifa Mohamed Hassan, Wen Zhao, Tingting Qin
    Phytomedicine.2024; 126: 155315.     CrossRef
  • Non-Pharmacological Approach to Diet and Exercise in Metabolic-Associated Fatty Liver Disease: Bridging the Gap between Research and Clinical Practice
    Hassam Ali, Muhammad Shahzil, Vishali Moond, Maria Shahzad, Abhay Thandavaram, Alina Sehar, Haniya Waseem, Taha Siddiqui, Dushyant Singh Dahiya, Pratik Patel, Hans Tillmann
    Journal of Personalized Medicine.2024; 14(1): 61.     CrossRef
  • Mortality in metabolic dysfunction-associated steatotic liver disease: A nationwide population-based cohort study
    Eugene Han, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Sang Hoon Ahn, Yong-ho Lee, Seung Up Kim
    Metabolism.2024; 152: 155789.     CrossRef
  • Performance Evaluation of a Novel Non-Invasive Test for the Detection of Advanced Liver Fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease
    Anna Stefanska, Katarzyna Bergmann, Szymon Suwała, Aneta Mankowska-Cyl, Marek Kozinski, Roman Junik, Magdalena Krintus, Mauro Panteghini
    Metabolites.2024; 14(1): 52.     CrossRef
  • Performance of noninvasive seromarkers in predicting liver fibrosis among MAFLD patients with or without viral hepatitis
    Chung‐Feng Huang, Po‐Cheng Liang, Chih‐Wen Wang, Tyng‐Yuan Jang, Po‐Yao Hsu, Pei‐Chien Tsai, Yu‐Ju Wei, Ming‐Lun Yeh, Ming‐Yen Hsieh, Yi‐Hung Lin, Chao‐Kuan Huang, Chia‐Yen Dai, Jee‐Fu Huang, Wan‐Long Chuang, Ming‐Lung Yu
    The Kaohsiung Journal of Medical Sciences.2024; 40(4): 374.     CrossRef
  • Time-restricted eating and supervised exercise for improving hepatic steatosis and cardiometabolic health in adults with obesity: protocol for the TEMPUS randomised controlled trial
    Alba Camacho-Cardenosa, Antonio Clavero-Jimeno, Juan J Martin-Olmedo, Francisco Amaro-Gahete, Rocío Cupeiro, María Trinidad González Cejudo, Patricia Virginia García Pérez, Carlos Hernández-Martínez, Raquel Sevilla-Lorente, Alejandro De-la-O, Alejandro Ló
    BMJ Open.2024; 14(1): e078472.     CrossRef
  • Association of sex-specific body mass index and waist circumference trajectories with non-alcoholic fatty liver disease incidence based on growth mixture modeling
    Tengrui Cao, Chao Tong, Qiang Li, Yumei Han, Aheyeerke Halengbieke, Xuetong Ni, Bo Gao, Deqiang Zheng, Xinghua Yang
    Nutrition, Metabolism and Cardiovascular Diseases.2024; 34(5): 1245.     CrossRef
  • Increased risk of colorectal adenomas with metabolic-associated fatty liver disease components
    Dongsheng Ran, ChunLing Xin, Yingcai Ma, Yanyan Lu
    Clinics and Research in Hepatology and Gastroenterology.2024; 48(3): 102302.     CrossRef
  • A Cross-Sectional Investigation for Prevalence and Risk Factors of Non-Alcoholic Fatty Liver Disease in Tibetan College Students in Mainland
    娟 周
    Advances in Clinical Medicine.2024; 14(02): 2843.     CrossRef
  • The Global Epidemic of Metabolic Fatty Liver Disease
    Ethan C. Z. Lee, Vickram V. Anand, Alex C. Razavi, Pamela L. Alebna, Mark D. Muthiah, Mohammad S. Siddiqui, Nicholas W. S. Chew, Anurag Mehta
    Current Cardiology Reports.2024; 26(4): 199.     CrossRef
  • Liver sinusoidal endothelial cells as potential drivers of liver fibrosis (Review)
    Jiaqin Gao, Bin Zuo, Yang He
    Molecular Medicine Reports.2024;[Epub]     CrossRef
  • Evolving role of semaglutide in NAFLD: in combination, weekly and oral administration
    Evgenia Koureta, Evangelos Cholongitas
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Association between remnant cholesterol and insulin resistance levels in patients with metabolic-associated fatty liver disease
    Shuang Wang, Qiang Zhang, Bo Qin
    Scientific Reports.2024;[Epub]     CrossRef
  • Identification of crosstalk genes relating to ECM‐receptor interaction genes in MASH and DN using bioinformatics and machine learning
    Chao Chen, Yuxi He, Ying Ni, Zhanming Tang, Wensheng Zhang
    Journal of Cellular and Molecular Medicine.2024;[Epub]     CrossRef
  • Serum PRO‐C3 is useful for risk prediction and fibrosis assessment in MAFLD with chronic kidney disease in an Asian cohort
    Liang‐Jie Tang, Dan‐Qin Sun, Sherlot Juan Song, Terry Cheuk‐Fung Yip, Grace Lai‐Hung Wong, Pei‐Wu Zhu, Sui‐Dan Chen, Morten Karsdal, Diana Julie Leeming, Pei Jiang, Cong Wang, Qiang Chen, Christopher D. Byrne, Giovanni Targher, Mohammed Eslam, Jacob Georg
    Liver International.2024; 44(5): 1129.     CrossRef
  • Non-invasive diagnosis of non-alcoholic fatty liver disease: Current status and future perspective
    Jia-Lan Wang, Su-Wen Jiang, Ai-Rong Hu, Ai-Wu Zhou, Ting Hu, Hong-Shan Li, Ying Fan, Ken Lin
    Heliyon.2024; 10(5): e27325.     CrossRef
  • Association of multiple serum minerals and vitamins with metabolic dysfunction-associated fatty liver disease in US adults: National Health and Nutrition Examination Survey 2017–2018
    Peisen Guo, Jiahui Yu
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease: current therapeutic strategies
    Khamis Al Hashmi, Rosaria Vincenza Giglio, Anca Pantea Stoian, Angelo Maria Patti, Khalid Al Waili, Khalid Al Rasadi, Marcello Ciaccio, Manfredi Rizzo
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • Depression and hepatobiliary diseases: a bidirectional Mendelian randomization study
    Yu Kong, Zhongcai Yao, Lingli Ren, Liqin Zhou, Jinkai Zhao, Yuanyuan Qian, Dayong Lou
    Frontiers in Psychiatry.2024;[Epub]     CrossRef
  • A universal plasma metabolites-derived signature predicts cardiovascular disease risk in MAFLD
    Zhonglin Li, Rui Gong, Huikuan Chu, Junchao Zeng, Can Chen, Sanping Xu, Lilin Hu, Wenkang Gao, Li Zhang, Hang Yuan, Zilu Cheng, Cheng Wang, Meng Du, Qingjing Zhu, Li Zhang, Lin Rong, Xiaoqing Hu, Ling Yang
    Atherosclerosis.2024; 392: 117526.     CrossRef
  • Hydroxytyrosol Linoleoyl Ether Ameliorates Metabolic-Associated Fatty Liver Disease Symptoms in Obese Zucker Rats
    Rubén Tovar, Marialuisa de Ceglia, Miguel Rodríguez-Pozo, Antonio Vargas, Ana Gavito, Juan Suárez, Anna Boronat, Rafael de la Torre, Fernando Rodríguez de Fonseca, Elena Baixeras, Juan Decara
    ACS Pharmacology & Translational Science.2024; 7(5): 1571.     CrossRef
  • Type 1 diabetes mellitus and non-alcoholic fatty liver disease: a two-sample Mendelian randomization study
    Lin Tuo, Li-ting Yan, Yi Liu, Xing-xiang Yang
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Examining the Pathogenesis of MAFLD and the Medicinal Properties of Natural Products from a Metabolic Perspective
    Yansong Fu, Zhipeng Wang, Hong Qin
    Metabolites.2024; 14(4): 218.     CrossRef
  • Evidence related to a vegetarian diet and metabolic dysfunction-associated steatotic liver disease: protocol for a scoping review
    Kasey Moss, Victor Gitman, M Ines Pinto Sanchez, Simon Oczkowski, David Armstrong, Saumya Jayakumar, Constantine Jason Karvellas, Nazia Selzner, Joanna Dionne
    BMJ Open.2024; 14(4): e079750.     CrossRef
  • Risk of Hepatocellular Carcinoma by Steatotic Liver Disease and Its Newly Proposed Subclassification
    Byeong Geun Song, Aryoung Kim, Myung Ji Goh, Wonseok Kang, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Dong Hyun Sinn
    Liver Cancer.2024; 13(5): 561.     CrossRef
  • Prevalence of Nonalcoholic Fatty Liver Disease [NAFLD] and Metabolic dysfunction associated Fatty Liver Disease [MAFLD] in patients with Irritable Bowel Syndrome [IBS]
    Md. Musab Khalil, Sirajam Munira, Md. Mahbubul Alam, Al Mahmood Appolo, Musatafa Md. Abu Sayeed, Atikul Islam, Narwana Khaleque, Mohammad Faisal, Arifa Tasnim, Ruma Najnin, Mahmudur Rahman, Enamul Karim, Md. Golam Kibria
    SN Comprehensive Clinical Medicine.2024;[Epub]     CrossRef
  • Positive association between insulin resistance and fatty liver disease in psoriasis: evidence from a cross-sectional study
    Xiaoyuan Zhong, Dawei Huang, Rongfen Chen, Lingling Yao, Rui Ma, Yingyuan Yu, Yuxiong Jiang, Luyang Kong, Jiajing Lu, Ying Li, Yuling Shi
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Genome-wide association study of metabolic dysfunction-associated fatty liver disease in a Korean population
    Young Lee, Eun Ju Cho, Eun Kyung Choe, Min-Sun Kwak, Jong In Yang, Seung-Won Oh, Jeong Yoon Yim, Goh Eun Chung
    Scientific Reports.2024;[Epub]     CrossRef
  • Essential Oils for the Treatment and Management of Nonalcoholic Fatty Liver Disease (NAFLD)
    Taehwa Kim, Mohammad Al Mijan, Jeonga Lee, Jungmi Yun, Jae Heun Chung, Soo Min Son, Ryuk Jun Kwon
    Natural Product Communications.2024;[Epub]     CrossRef
  • Curcuma wenyujin rhizomes extract ameliorates lipid accumulation
    Hong Wang, Lijia Chen, Ruiyu Zhang, Guanying Zhang, Jingwen Liu, Fujiang Guo
    Fitoterapia.2024; 175: 105957.     CrossRef
  • The Role of PNPLA3_rs738409 Gene Variant, Lifestyle Factors, and Bioactive Compounds in Nonalcoholic Fatty Liver Disease: A Population-Based and Molecular Approach towards Healthy Nutrition
    Meiling Liu, Sunmin Park
    Nutrients.2024; 16(8): 1239.     CrossRef
  • Prevalence of metabolic dysfunction-associated fatty liver disease and its association with glycemic control in persons with type 2 diabetes in Africa: A systematic review and meta-analysis
    Emmanuel Ekpor, Samuel Akyirem, Precious Adade Duodu, Bert B. Little
    PLOS Global Public Health.2024; 4(5): e0002835.     CrossRef
  • Role of FXR in the development of NAFLD and intervention strategies of small molecules
    Jiachan Long, Yuanhang Xu, Xuerong Zhang, Bingxing Wu, Caiyan Wang
    Archives of Biochemistry and Biophysics.2024; 757: 110024.     CrossRef
  • Influence of nonalcoholic fatty liver disease severity on carotid adventitial vasa vasorum
    Josep León-Mengíbar, Enric Sánchez, Ferrán Herrerías, Mari Cruz De La Fuente, Maite Santamaría, José Manuel Valdivielso, Marcelino Bermúdez-López, Eva Castro, Judit Pallarés, Xavier Matias-Guiu, Felip Vilardell, Assumpta Caixàs, Marta Bueno, Raquel Martí,
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Lifestyle intervention for metabolic dysfunction-associated fatty liver disease: a 24-h integrated behavior perspective
    Shelley E. Keating, Yogesh Chawla, Arka De, Elena S. George
    Hepatology International.2024; 18(S2): 959.     CrossRef
  • Metabolic dysfunction-associated fatty liver disease/metabolic dysfunction-associated steatotic liver disease: general provisions
    O.E. Abaturov, A.O. Nikulina
    CHILD`S HEALTH.2024; 19(2): 107.     CrossRef
  • Early life exposure to vitamin D deficiency impairs molecular mechanisms that regulate liver cholesterol biosynthesis, energy metabolism, inflammation, and detoxification
    Megan M. Knuth, Jing Xue, Marwa Elnagheeb, Raad Z. Gharaibeh, Sarah A. Schoenrock, Susan McRitchie, Cory Brouwer, Susan J. Sumner, Lisa Tarantino, William Valdar, R. Scott Rector, Jeremy M. Simon, Folami Ideraabdullah
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Deconvolution analysis identified altered hepatic cell landscape in primary sclerosing cholangitis and primary biliary cholangitis
    Hoang Nam Pham, Linh Pham, Keisaku Sato
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Letter to the editor: Comment on “The effect of dairy products on liver fat and metabolic risk markers in males with abdominal obesity – A four-arm randomized controlled trial”
    Luping Quan, Chao Ding, Yumeng Jin, Yaping Li
    Clinical Nutrition.2024; 43(6): 1595.     CrossRef
  • Metabolic dysfunction associated steatotic liver disease in patients with plaque psoriasis: a case–control study and serological comparison
    Zheng Lin, Yue-yi Shi, Lu-yan Yu, Chen-xi Ma, Si-yi Pan, Yuan Dou, Qiu-jun Zhou, Yi Cao
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Age at menopause and risk of metabolic dysfunction-associated fatty liver disease: A 14-year cohort study
    Ehn-Young Kim, Yae-Ji Lee, Yu-Jin Kwon, Ji-Won Lee
    Digestive and Liver Disease.2024; 56(11): 1880.     CrossRef
  • MAFLD and glomerular hyperfiltration in subjects with normoglycemia, prediabetes and type 2 diabetes: A cross‐sectional population study
    Manuela Abbate, Aneliya Parvanova, Ángel Arturo López‐González, Aina M. Yañez, Miquel Bennasar‐Veny, José Ignacio Ramírez‐Manent, Elia Reseghetti, Piero Ruggenenti
    Diabetes/Metabolism Research and Reviews.2024;[Epub]     CrossRef
  • Associations of perfluoroalkyl substances with metabolic-associated fatty liver disease and non-alcoholic fatty liver disease: NHANES 2017–2018
    Yuxiao Zhang, Min Zhang, Shanjiamei Jiang, Heng Hu, Xinzhi Wang, Fan Yu, Yue’e Huang, Yali Liang
    Cancer Causes & Control.2024; 35(9): 1271.     CrossRef
  • Global perspective on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis ‐ prevalence, clinical impact, economic implications and management strategies
    Pegah Golabi, Soroor Owrangi, Zobair M. Younossi
    Alimentary Pharmacology & Therapeutics.2024;[Epub]     CrossRef
  • Azorella compacta Organic Extracts Exacerbate Metabolic Dysfunction-Associated Fatty Liver Disease in Mice Fed a High-Fat Diet
    Jessica Zúñiga-Hernandez, Matías Quiñones San Martin, Benjamín Figueroa, Ulises Novoa, Francisco A. Monsalve, Mitchell Bacho, Aurelio San-Martin, Daniel R. González
    Pharmaceuticals.2024; 17(6): 746.     CrossRef
  • Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β
    Joey A. Muns, Erik Schooten, Rychon D. J. van Dasselaar, Yvet E. Noordman, Kevin Adamzek, Arthur C. Eibergen, Sebas D. Pronk, Sagel Cali, Niels J. Sijbrandi, Eugen Merkul, Sabrina Oliveira, Paul M.P. van Bergen en Henegouwen, R. Bart Takkenberg, Joanne Ve
    European Journal of Nuclear Medicine and Molecular Imaging.2024; 51(12): 3545.     CrossRef
  • Comparative study of MAFLD as a predictor of metabolic disease treatment for NAFLD
    Jin Imai, Shinji Takashimizu, Nana Suzuki, Kana Ohshinden, Kana Sawamoto, Yusuke Mishima, Kota Tsuruya, Yoshitaka Arase, Mitsuhiko Yamano, Noriaki Kishimoto, Chizumi Yamada, Nagamu Inoue, Kengo Moriyama, Akiyasu Baba, Hidekazu Suzuki, Tatehiro Kagawa, Yas
    Scientific Reports.2024;[Epub]     CrossRef
  • Ultrasound Shear Wave Elastography Evaluation of the Liver and Implications for Perioperative Medicine
    Giancarlo Suffredini, Wei Dong Gao, Jeffrey M. Dodd-o
    Journal of Clinical Medicine.2024; 13(13): 3633.     CrossRef
  • Importance of the gut microbiota in the gut-liver axis in normal and liver disease
    Stanislav Kotlyarov
    World Journal of Hepatology.2024; 16(6): 878.     CrossRef
  • Interplay of Mediterranean-diet adherence, genetic factors, and metabolic dysfunction-associated steatotic liver disease risk in Korea
    Yu-Jin Kwon, Ja-Eun Choi, Kyung-Won Hong, Ji-Won Lee
    Journal of Translational Medicine.2024;[Epub]     CrossRef
  • MAFLD Pandemic: Updates in Pharmacotherapeutic Approach Development
    Farah Khaznadar, Omar Khaznadar, Ana Petrovic, Marija Hefer, Fabian Gjoni, Stefan Gjoni, Justinija Steiner, Martina Smolic, Kristina Bojanic
    Current Issues in Molecular Biology.2024; 46(7): 6300.     CrossRef
  • Breaking Barriers: Enhancing Statins Utilization for Cardiovascular Protection in MAFLD
    Faraz Arshad
    The American Journal of Medicine.2024; 137(7): e142.     CrossRef
  • Insight into the regulatory mechanism of m6A modification: From MAFLD to hepatocellular carcinoma
    Xuan Zha, Zewei Gao, Min Li, Xueli Xia, Zhenwei Mao, Shengjun Wang
    Biomedicine & Pharmacotherapy.2024; 177: 116966.     CrossRef
  • Alanine aminotransferase predicts incident steatotic liver disease of metabolic etiology: Long life to the old biomarker!
    Amedeo Lonardo
    World Journal of Gastroenterology.2024; 30(24): 3016.     CrossRef
  • Diosgenin attenuates metabolic-associated fatty liver disease through the hepatic NLRP3 inflammasome-dependent signaling pathway
    Wenfei Yu, Guoliang Yin, Suwen Chen, Xin Zhang, Decheng Meng, Linya Wang, Hongshuai Liu, Wenying Jiang, Yuqing Sun, Fengxia Zhang
    International Immunopharmacology.2024; 138: 112581.     CrossRef
  • Proinflammatory interleukins 2, 6 and tumor necrosis factor alpha in patients with hypertension and diabetes mellitus depending on the presence of metabolic-associated liver steatosis
    O.M. Radchenko, O.J. Komarytsia, M.O. Borovets, R.S. Ivasivka, R.R. Guta
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2024; 20(3): 200.     CrossRef
  • A New Korean Nomenclature for Steatotic Liver Disease

    The Korean Journal of Gastroenterology.2024; 84(1): 1.     CrossRef
  • Disinfection Byproducts of Haloacetaldehydes Disrupt Hepatic Lipid Metabolism and Induce Lipotoxicity in High-Fat Culture Conditions
    Lili Yang, Zhiqiang Jiang, Lan Yang, Weiwei Zheng, Yu Chen, Fei Qu, M. James C. Crabbe, Yubin Zhang, Melvin E. Andersen, Yuxin Zheng, Weidong Qu
    Environmental Science & Technology.2024; 58(28): 12356.     CrossRef
  • Association between life’s essential 8 and metabolic dysfunction-associated steatotic liver disease among US adults
    Zheng Wang, Bohan Huang, Yixuan Ding, Feng Cao, Fei Li, Prof Fei Li
    Archives of Public Health.2024;[Epub]     CrossRef
  • Metformin Lowers Plasma Triacylglycerol Levels in Mice with Impaired Carnitine Biosynthesis and Fatty Liver
    Bodil Bjørndal, Tra-My Thi Le, Elin Strand, Lise Madsen, Rolf K. Berge
    SynBio.2024; 2(3): 240.     CrossRef
  • The Role of Antioxidants in the Treatment of Metabolic Dysfunction-Associated Fatty Liver Disease: A Systematic Review
    Kiana Mohammadian, Fatemeh Fakhar, Shayan Keramat, Agata Stanek
    Antioxidants.2024; 13(7): 797.     CrossRef
  • Galectin-3 and Severity of Liver Fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease
    Mohammadjavad Sotoudeheian
    Protein & Peptide Letters.2024; 31(4): 290.     CrossRef
  • In vitro osteoclast differentiation enhanced by hepatocyte supernatants from high-fat diet mice
    Yan Wang, Fangli Zhou, Siyi Shu, Yunhong Wu, Haoming Tian, Yujue Li, Xiang Chen
    Biochemistry and Biophysics Reports.2024; 39: 101788.     CrossRef
  • Novel insights into autophagy in gastrointestinal pathologies, mechanisms in metabolic dysfunction-associated fatty liver disease and acute liver failure
    Tsvetelina Velikova, Milena Gulinac
    World Journal of Gastroenterology.2024; 30(27): 3273.     CrossRef
  • The Renoprotective Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i)—A Narrative Review
    Liana Iordan, Laura Gaita, Romulus Timar, Vlad Avram, Adrian Sturza, Bogdan Timar
    International Journal of Molecular Sciences.2024; 25(13): 7057.     CrossRef
  • Genotypic variation in CYP2E1, GCKR, and PNPLA3 among nonalcoholic steatohepatitis patients of Turkish origin
    Abbas Ali Husseini
    Molecular Biology Reports.2024;[Epub]     CrossRef
  • Hepatic Steatosis Can Be Partly Generated by the Gut Microbiota–Mitochondria Axis via 2-Oleoyl Glycerol and Reversed by a Combination of Soy Protein, Chia Oil, Curcumin and Nopal
    Mónica Sánchez-Tapia, Sandra Tobón-Cornejo, Lilia G. Noriega, Natalia Vázquez-Manjarrez, Diana Coutiño-Hernández, Omar Granados-Portillo, Berenice M. Román-Calleja, Astrid Ruíz-Margáin, Ricardo U. Macías-Rodríguez, Armando R. Tovar, Nimbe Torres
    Nutrients.2024; 16(16): 2594.     CrossRef
  • TG: HDL, AST: ALT, A:G Ratios in Alcoholic and Non-alcoholic Fatty Liver patients
    Abhinav Manish, Anuradha Bharosay, Kanchan Negi, Ritesh Srivastava
    Journal of Research in Applied and Basic Medical Sciences.2024; 10(3): 279.     CrossRef
  • Protective effects of syringic acid in nonalcoholic fatty liver in rats through regulation of Nrf2/HO‐1 signaling pathway
    Simiao Zhang, Sheng Zheng, Ya Li, Juan Yang, Xiaozhou Mao, Tao Liu, Qiuxin Zhang, ZhiPeng Fu, Xing Zhu, Long Xu
    Journal of Biochemical and Molecular Toxicology.2024;[Epub]     CrossRef
  • SGLT2 inhibition leads to a restoration of hepatic and circulating metabolites involved in the folate cycle and pyrimidine biosynthesis
    Ileana Mendez Espinoza, Elijah N. D. Choos, Carolyn M. Ecelbarger, Blythe D. Shepard
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2024; 327(2): G235.     CrossRef
  • Carbon monoxide-loaded red blood cells ameliorate metabolic dysfunction-associated steatohepatitis progression via enhancing AMP-activated protein kinase activity and inhibiting Kupffer cell activation
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