A Case of Hypereosinophilic Syndrome with Hepatic and Gastrointestinal Involvement

Korean J Hepatol > Volume 6(2); 2000 > Article

The Korean Journal of Hepatology 2000;6(2): 229-235.

증례 : 간 및 위장관 침윤을 동반한 특발성 과호산구 증후군 1예 ( A Case of Hypereosinophilic Syndrome with Hepatic and Gastrointestinal Involvement )

A Case of Hypereosinophilic Syndrome with Hepatic and Gastrointestinal Involvement

Duc ky Rhee,Hyun Min Shin,Doo Yul Ryu,Jong Hyung Kim,Dong In Hawng,Dong Joo Lee,Seok Eun Kim,Suk Joon Park

Department of Internal medicine Daelim Saint Mary 's Hospital, Seoul, Korea

ABSTRACT

Hypereosinophilic syndrome is characterized by prolonged eosinophilia of blood and tissue without an identifiable underlying cause and multiorgan system dysfunction by eosinophil-related tissue damage to variable organs: liver, heart, lung, kidney, gastrointestinal tract, skin, nerve. Some case of hypereosinophilic syndrome with hepatic and gastrointestinal involvement have been reported, but not much. We are reporting a case of hypereosinophilic syndrome with hepatic and gastrointestinal involvement in 56-year-old man who presented general weakness and epigastric discomfort. In abdominal US, CT and MRI, intrahepatic multifocal ill-defined lesions were detected. The patient was treated with prednisolone for 16 weeks and recovered from eosinophilia and gastric involvement. A gastric biopsy was taken to confirm recovery. Also, the ill-defined lesions in US and CT disappeared after treatment.(Korean J Hepatol 2000;6:229-235)

KeyWords: Hypereosinophilic syndrome, Hepatic involement