A case report of alverine-citrate-induced acute hepatitis

doi:2010.16.1.75

Korean J Hepatol > Volume 16(1); 2010 > Article

The Korean Journal of Hepatology 2010;16(1): 75-78.
doi: https://doi.org/10.3350/kjhep.2010.16.1.75

A case report of alverine-citrate-induced acute hepatitis

Jee Young Han, M.D., Jin-Woo Lee, M.D., Joon Mee Kim, M.D.1, Kowoon Joo, M.D., Ung Chon, M.D., Jung Il Lee, M.D., Seok Jeong, M.D., Don Haeng Lee, M.D., Young Soo Kim, M.D., Kyung Sun Min, M.D.

Department of Internal Medicine and 1Department of Pathology, Inha University School of Medicine, Incheon, Korea

ABSTRACT

Alverine citrate is one of the most commonly used antispasmodic drugs for patients with irritable bowel syndrome. Alverine-citrate-induced hepatotoxicity is extremely rare, with only a few cases having been reported worldwide. We present a case of a 75-year-old female patient who experienced complicated jaundice and abdominal discomfort after taking alverine citrate. Other causes of hepatitis were ruled out and the results of the liver function test returned to normal after ceasing the drug. This is the first case report in Korea of alverine-citrate-induced hepatotoxicity. (Korean J Hepatol 2010;16:75-78)

KeyWords: Alverine; Toxicity; Liver