Skip to main navigation Skip to main content

CMH : Clinical and Molecular Hepatology

OPEN ACCESS
Search
Advanced Search
ABOUT
BROWSE ARTICLES
FOR CONTRIBUTORS

Articles

Page Path

Correspondence

Correspondence on Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”

Joo Hyun Oh1, Dong Hyun Sinn2orcid
Clinical and Molecular Hepatology 2023;29(3):820-820.
Published online: May 19, 2023

1Department of Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea

2Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Corresponding author : Dong Hyun Sinn Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea Tel: +82-2-3410-3409, Fax: +82-2-3410-6983, E-mail: dh.sinn@samsung.com

Editor: Seung Up Kim, Yonsei University College of Medicine, Korea

• Received: April 4, 2023   • Accepted: April 5, 2023

Copyright © 2023 by The Korean Association for the Study of the Liver

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • 4,859 Views
  • 38 Download
prev next

Full Article

Download PDF Download PDF
See the letter "Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”" on page 812.
Dear Editor,
We would like to thank Professor Emiroglu [1] for showing interest in our paper. According to the guidelines established by the American Association for the Study of Liver Disease, the upper limit of normal for alanine aminotransferase (ALT) levels in healthy adult males is reported to range between 29–33 U/L [2]. However, to accommodate for differences in repeat testing for the same sample and to improve management decisions [3], it has been recommended to update the upper limit of normal for ALT in males to 35 U/L. Therefore, we agree that “<35 U/L” would be a more appropriate reference range for guidance. We will be mindful of any small errors that could cause confusion in decision-making.

Authors’ contribution

JHO drafted the manuscript. DHS reviewed and finalized the manuscript.

Conflicts of Interest

The authors have no conflicts to disclose.

ALT

alanine aminotransferase
  • 1. Emiroglu HH. The upper limit of normal for ALT in males according to AASLD guideline. Clin Mol Hepatol 2023 May 8; doi: 10.3350/cmh.2023.0132.
  • 2. Terrault NA, Lok ASF, McMahon BJ, Chang KM, Hwang JP, Jonas MM, et al. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology 2018;67:1560-1599.
  • 3. Dutta A, Saha C, Johnson CS, Chalasani N. Variability in the upper limit of normal for serum alanine aminotransferase levels: a statewide study. Hepatology 2009;50:1957-1962.

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Correspondence on Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”
Clin Mol Hepatol. 2023;29(3):820-820.   Published online May 19, 2023
DOI: https://doi.org/10.3350/cmh.2023.0135
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Correspondence on Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”
Clin Mol Hepatol. 2023;29(3):820-820.   Published online May 19, 2023
DOI: https://doi.org/10.3350/cmh.2023.0135
Close

Related articles

Correspondence on Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”
Correspondence on Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”
CMH : Clinical and Molecular Hepatology
Twitter

ABOUT

BROWSE ARTICLES

FOR CONTRIBUTORS

© The Korean Association for the Study of the Liver.