Letter 2 regarding “Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma”

Article information

Clin Mol Hepatol. 2023;29(3):815-816
Publication date (electronic) : 2023 May 24
doi : https://doi.org/10.3350/cmh.2023.0170
1Samraong, Cambodia
2Chandigarh University, Punjab, India
3Joesph Ayobabalola University, Ikeji-Arakeji, Nigeria
Corresponding author : Amnuay Kleebayoon Samraong, Private Academic Consultant 222 Main Road, Samraong Commune, 210308 Samraong, Cambodia Tel: +8557878989636, Fax: +855787898963, E-mail: amnuaykleebai@gmail.com
Editor: Seung Samraong, Up Kim, Yonsei University College of Medicine, Korea
Received 2023 May 18; Revised 2023 May 22; Accepted 2023 May 23.

Dear Editor,

We found that the article on “Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma [1]” is interesting. Yeo et al. [1] examined the reliability and correctness of ChatGPT when it came to cirrhosis and hepatocellular carcinoma (HCC) knowledge, management, and emotional support. Yeo et al. [1] conducted an analysis of the ChatGPT replies on the management of cirrhosis, HCC, and pertinent emotional support to determine the areas of robustness and limitations. According to Yeo et al. [1], ChatGPT may serve as an additional informational tool for patients and doctors to enhance outcomes.

We both acknowledge the importance of giving ethical technology use significant thought, particularly in view of the rapidly developing field of artificial intelligence. Without human assessment, artificial intelligence (AI) shouldn’t be utilized to develop, analyze, or approve crucial information [2]. An important and contentious topic is the veracity of the data in ChatGPT. However, it’s crucial to consider how AI should be applied ethically. The ChatGPT may generate information that is immediately relevant even without user interaction. This is done to make other crimes, like plagiarism, more likely. Abuse could increase as a result of ineffective intake management strategies. It might still be useful, though. It might still be useful, though. For instance, it might be used to detect plagiarism and ghostwriting automatically. Everyone acknowledges that AI needs a more solid base. We can all agree that a cutting-edge approach is necessary for AI to operate effectively. Establishing ethically sound and efficient use of the evolving AI is now crucial.


Authors’ contribution

Amnuay Kleebayoon 50% ideas, writing, analyzing, approval for submission. Viroj Wiwanitkit 50% ideas, supervision, approval for submission.

Conflicts of Interest

The authors have no conflicts to disclose.



hepatocellular carcinoma


artificial intelligence


1. Yeo YH, Samaan JS, Ng WH, Ting PS, Trivedi H, Vipani A, et al. Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma. Clin Mol Hepatol 2023;Mar. 22. doi: 10.3350/cmh.2023.0089.
2. Kleebayoon A, Wiwanitkit V. Artificial intelligence, chatbots, plagiarism and basic honesty: Comment. Cell Mol Bioeng 2023;16:173–174.

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