| A Case of the Treatment in an Adult with Hepatic Undifferentiated (Embryonal) Sarcoma |
| Kyoung-Tae Kim, M.D.1, Sang-Young Han, M.D.1, Eun-Hee Park, M.D.1, Jin-Seok Jang, M.D.1,
Myung-Hwan Roh, M.D.1, Sung-Wook Lee, M.D.1, Jin-Sook Jeong, M.D.2 |
| Department of Internal Medicine1, Department of Laboratory Medicine2, Dong-A University College of Medicine, Busan, Korea |
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| ABSTRACT |
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Undifferentiated embryonal sarcoma is a rare primary malignant neoplasm of the liver. Undifferentiated
sarcoma of the liver in adult is an uncommon hepatic tumor of mesenchymal origin, generally considered an
aggressive neoplasm with an unfavorable prognosis. We present a case of undifferentiated sarcoma in a
61-year-old woman. CT scan demonstrated a large heterogenous, exophytic growing hepatic mass in the right
lobe with pulmonary metastatic nodules. US guided liver biopsy was done and pathological findings of the liver
specimen revealed that isolated or grouped round pleomorphic cells and spindle to stellate cells were present.
Immunohistochemical stain showed that tumor cells expressed positivity for vimentin and partially positivity or
negativity for cytokeratin. She was diagnosed as having undifferentiated sarcoma of the liver. She received
seven courses of VAIA chemotherapy by CWS protocols. Chemotherapy was efficacious and the size of the
tumor decreased considerably after the treatment. No tumor recurrence for 12 months is noted. (Korean J
Hepatol 2007;13:96-102) |
| KeyWords:
Sarcoma; Liver; Chemotherapy |
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