Review

August 19, 2024


Epidemiology of metabolic dysfunction-associated steatotic liver disease
Zobair M. Younossi, Markos Kalligeros, Linda Henry
Clin Mol Hepatol. 2025;31(Suppl):S32-S50.

Review

June 27, 2024


Role of noninvasive tests in the prognostication of metabolic dysfunction-associated steatotic liver disease
Yue Wang, Sherlot Juan Song, Yichong Jiang, et al.
Clin Mol Hepatol. 2025;31(Suppl):S51-S75.

Review

August 5, 2024


Precision medicine and nucleotide-based therapeutics to treat steatotic liver disease
Andrea Caddeo, Stefano Romeo
Clin Mol Hepatol. 2025;31(Suppl):S76-S93.

Review

November 28, 2024


Microbiome-centered therapies for the management of metabolic dysfunction-associated steatotic liver disease
Huma Saeed, Luis Antonio Díaz, Antonio Gil-Gómez, et al.
Clin Mol Hepatol. 2025;31(Suppl):S94-S111.

Review

October 31, 2024


Alcohol-associated liver disease: Natural history, management and novel targeted therapies
Edilmar Alvarado-Tapias, Elisa Pose, Jordi Gratacós-Ginès, et al.
Clin Mol Hepatol. 2025;31(Suppl):S112-S133.

Review

January 22, 2025


Update on the treatment navigation for functional cure of chronic hepatitis B: Expert consensus 2.0
Di Wu, Jia-Horng Kao, Teerha Piratvisuth, et al.
Clin Mol Hepatol. 2025;31(Suppl):S134-S164.

Review

November 14, 2024


Prospect of emerging treatments for hepatitis B virus functional cure
Rex Wan-Hin Hui, Lung-Yi Mak, James Fung, et al.
Clin Mol Hepatol. 2025;31(Suppl):S165-181.

Review

November 21, 2024


Mechanisms of hepatocellular carcinoma and cirrhosis development in concurrent steatotic liver disease and chronic hepatitis B
Saisai Zhang, Lung-Yi Mak, Man-Fung Yuen, et al.
Clin Mol Hepatol. 2025;31(Suppl):S182-S195.

Review

November 11, 2024


Hepatitis E as a trigger for acute-on-chronic liver failure
Maria Buti, Juan Carlos Ruiz-Cobo, Rafael Esteban, et al.
Clin Mol Hepatol. 2025;31(Suppl):S196-S204.

Review

February 18, 2025


Prediction and prevention of post-procedural bleedings in patients with cirrhosis
Alix Riescher-Tuczkiewicz, Pierre-Emmanuel Rautou
Clin Mol Hepatol. 2025;31(Suppl):S205-S227.

Review

December 26, 2024


Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment
Soo Young Hwang, Pojsakorn Danpanichkul, Vatche Agopian, et al.
Clin Mol Hepatol. 2025;31(Suppl):S228-S254.

Review

November 28, 2024


Liquid biopsy in hepatocellular carcinoma: Challenges, advances, and clinical implications
Jaeho Park, Yi-Te Lee, Vatche G. Agopian, et al.
Clin Mol Hepatol. 2025;31(Suppl):S255-S284.

Review

August 19, 2024


Criteria and prognostic models for patients with hepatocellular carcinoma undergoing liver transplantation
Meng Sha, Jun Wang, Jie Cao, et al.
Clin Mol Hepatol. 2025;31(Suppl):S285-S300.

Review

December 10, 2024


Prediction and management of small-for-size syndrome in living donor liver transplantation
Jia-hao Law, Alfred Wei-Chieh Kow
Clin Mol Hepatol. 2025;31(Suppl):S301-S326.

Review

December 26, 2024


Liver organoids: Current advances and future applications for hepatology
Yohan Kim, Minseok Kang, Michael Girma Mamo, et al.
Clin Mol Hepatol. 2025;31(Suppl):S327-S348.


Articles in E-pub version are posted online ahead of regular printed publication.

Review
Tracking the trajectory of kidney dysfunction in cirrhosis: the acute kidney injury – chronic kidney disease spectrum
Vishnu Girish, Rakhi Maiwall
Received November 24, 2024  Accepted March 24, 2025  
View: 20   Download: 3
Editorial
GULP1, A Multifaceted Diagnostic Biomarker and Potential Therapeutic Target in Hepatocellular Carcinoma: Editorial on “GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma”
Yuhao Xie, Lu-Qi Cao, John Wurpel, Zhe-Sheng Chen
Received March 18, 2025  Accepted March 21, 2025  
View: 81   Download: 5
Besifovir: a viable option for long-term disease control in chronic hepatitis B
Wai-Kay Seto
Received March 15, 2025  Accepted March 20, 2025  
View: 53   Download: 3
Refining Portal Hypertension Assessment: The Clinical Significance of Spleen Stiffness Measurement in the Baveno VII Era
Do Seon Song
Received March 13, 2025  Accepted March 20, 2025  
View: 57   Download: 2
Letter to the Editor
Letter “Direct-acting antiviral therapy for patients with HCV-related hepatocellular carcinoma: A nationwide cohort study”
Qiong Wang, Zhongqing Qian, Xiaodi Yang, Deyan Chen, Xiaojing Wang, Fuliang Chen
Received March 13, 2025  Accepted March 19, 2025  
View: 74   Download: 3
Correspondence
Correspondence: Response to the Letter Regarding "GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma"
Hyung Seok Kim, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun
Received March 12, 2025  Accepted March 15, 2025  
View: 193   Download: 16
Editorial
Unveiling GULP1 as a Hepatocyte-Specific Role for Recurrence: Editorial on “GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma”
Pengde Lu, Ning Wang
Received March 11, 2025  Accepted March 15, 2025  
View: 151   Download: 13
A non-invasive risk stratification tool for hepatitis B-related liver cirrhosis: the Baveno VI-SSM combined model.
Ruiling He, Bingtian Dong, Xiaolong Qi
Received March 11, 2025  Accepted March 15, 2025  
View: 168   Download: 12
Predicting decompensation risk in compensated HBV cirrhosis: Eternal sunshine for a spotless mind?
Mathias Jachs, Mattias Mandorfer
Received March 11, 2025  Accepted March 15, 2025  
View: 130   Download: 8
Letter to the Editor
Critical Considerations in Evaluating the Therapeutic Potential of HK-660S for Primary Sclerosing Cholangitis
He Yizi, He Haifeng, Liang Qi, Xie Yongzhi
Received March 1, 2025  Accepted March 13, 2025  
View: 119   Download: 10
Original Article
Impact of components of metabolic syndrome on long-term outcomes of CHB with nucleos(t)ide analogue treatment
Rui Huang, Dae Won Jun, Hidenori Toyoda, Yao-Chun Hsu, Huy Trinh, Akito Nozaki, Toru Ishikawa, Tsunamasa Watanabe, Haruki Uojima, Daniel Q. Huang, Takashi Honda, Yasuhito Tanaka, Philip Vutien, Sebastián Marciano, Hiroshi Abe, Masaru Enomoto, Masanori Atsukawa, Hirokazu Takahashi, Kunihiko Tsuji, Koichi Takaguchi, Pei-Chien Tsai, Chia-Yen Dai, Jee-Fu Huang, Chung-Feng Huang, Ming-Lun Yeh, Eileen Yoon, Sung Eun Kim, Sang Bong Ahn, Gi-Ae Kim, Jang Han Jung, Soung Won Jeong, Hyunwoo Oh, Cheng-Hao Tseng, Masatoshi Ishigami, Angela Chau, Mayumi Maeda, Satoshi Yasuda, Makoto Chuma, Takanori Ito, Keigo Kawashima, Joanne Kimiko Liu, Adrian Gadano, Ritsuzo Kozuka, Norio Itokawa, Kaori Inoue, Tomonori Senoh, Jie Li, Wan-Long Chuang, Ramsey Cheung, Chao Wu, Ming-Lung Yu, Mindie H. Nguyen
Received November 27, 2024  Accepted March 14, 2025  
View: 428   Download: 33
Reply to Correspondence
SHOULD DIRECT-ACTING ANTIVIRAL BE CONSIDERED FOR ALL PATIENTS WITH HCV-RELATED HEPATOCELLULAR CARCINOMA?
Yan Ling ONG, Apichat KAEWDECH, Yu Jun WONG
Received March 5, 2025  Accepted March 10, 2025  
View: 166   Download: 8
Regulation of Hepatitis B Virus cccDNA by Metabolic Pathways
Hyeong-Jin Cho, Sung-Gyoo Park
Received March 4, 2025  Accepted March 9, 2025  
View: 242   Download: 32
Original Article
Molecular Classification of Hepatocellular Carcinoma based on Zoned Metabolic Feature and Oncogenic Signaling Pathway
Tomoko Aoki, Naoshi Nishida, Yutaka Kurebayashi, Kazuko Sakai, Naoto Fujiwara, Masakatsu Tsurusaki, Kohei Hanaoka, Masahiro Morita, Hirokazu Chishina, Masahiro Takita, Satoru Hagiwara, Hiroshi Ida, Kazuomi Ueshima, Yasunori Minami, Atsushi Takebe, Takaaki Murase, Keiko Kamei, Takuya Nakai, Ippei Matsumoto, Kazuto Nishio, Masatoshi Kudo
Received December 3, 2024  Accepted March 7, 2025  
View: 627   Download: 76
Letter to the Editor
Letter “GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma”
Juan Yang, Xinyi Li, Sheng Zheng
Received February 24, 2025  Accepted March 5, 2025  
View: 236   Download: 23
Letter to the Editor on “Current Burden of Steatotic Liver Disease and Fibrosis among Adults in the United States, 2017-2023”
Sisi Yang, Zhenxuan Ma
Received February 11, 2025  Accepted March 6, 2025  
View: 168   Download: 10
Correspondence
Emerging evidence supports direct-acting antiviral therapy for HCC patients beyond the early stage
Teng-Yu Lee, Pei-Chien Tsai, Shou-Wu Lee, Ming- Lung Yu
Received February 28, 2025  Accepted March 1, 2025  
View: 246   Download: 8
Reply to Correspondence
Reply to correspondence on “The Burden of Steatotic Liver Disease before and during the COVID Pandemic”
Jeayeon Park, Su Jong Yu
Received February 25, 2025  Accepted February 26, 2025  
View: 142   Download: 1
Research Letter
Mendelian randomization does not support the effects of G-CSF on decompensated liver disease
Li Liling, Wang Hui, Wang Hong, Huang Jinchang
Received February 27, 2025  Accepted March 1, 2025  
View: 252   Download: 26
Review
Liver Disease Trends in the Asia-Pacific Region for the Next 50 Years
Shuichiro Shiina, Javkhlan Maikhuu, Qing Deng, Terguunbileg Batsaikhan, Lariza Marie Canseco, Maki Tobari, Hitoshi Maruyama, Hiroaki Nagamatsu, Diana Alcantara-Payawal, Rino Gani, Yi-Hsiang Huang, Tawesak Tanwandee, Giovanni Galati, Yoon Jun Kim
Received January 15, 2025  Accepted February 26, 2025  
View: 320   Download: 22
Original Article
CD36 Promotes Iron Accumulation and Dysfunction in CD8+ T Cells via the p38-CEBPB-TfR1 Axis in Early-stage Hepatocellular Carcinoma
Yifei Qin, Fei Huo, Zhuan Feng, Jialu Hou, Yaxin Ding, Quancheng Wang, Yu Gui, Ziwei Yang, Jiali Yang, Gang Zhou, Ling Li, Jianli Jiang, Lingmin Kong, Shijie Wang, Gang Nan, Dingqiao Xu, Xiaohang Xie, Lijuan Wang, Qian He, Ruibin Yang, Peng Lin, Huijie Bian, Zhi-Nan Chen, Jiao Wu
Received November 3, 2024  Accepted March 1, 2025  
View: 501   Download: 90
Erratum
Erratum to ‘Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial’ [Clin Mol Hepatol 2024;30:807-823]
Sun Young Yim, Sung Hwan Lee, Seung-Woo Baek, Bohwa Sohn, Yun Seong Jeong, Sang-Hee Kang, Kena Park, Hyewon Park, Sunyoung S. Lee, Ahmed O. Kaseb, Young Nyun Park, Sun-Hee Leem, Michael A. Curran, Ji Hoon Kim, Ju-Seog Lee
DOI: https://doi.org/10.3350/cmh.2024.0333e    [Epub ahead of print]
View: 393   Download: 29
Reply to Correspondence
Reply to correspondence for “Metabolic dysfunction in patients following DAA-induced viral cure for HCV infection: a non-negligible risk to liver-related health”
Chen-Hua Liu, Yu-Ping Chang
Received February 21, 2025  Accepted February 22, 2025  
View: 148   Download: 10
Reply to correspondence on the Editorial “Bridging the Gap: The GOLM1-OPN-ABCG5 Axis in MASH and Gallstone Disease”
Nahee Hwang, Sungsoon Fang
Received February 20, 2025  Accepted February 22, 2025  
View: 216   Download: 11
Letter to the Editor
Re: "Bariatric Surgery Reduces Long-Term Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Cirrhosis"
Weixiong Zhu, Xuefan Zeng, Zengxi Yang, Yusheng Cheng, Wence Zhou
Received February 18, 2025  Accepted February 24, 2025  
View: 315   Download: 30
Correspondence
HCC predictors in routine practice for patients with chronic liver diseases
Tung-Hung Su, Jia-Horng Kao
Received February 18, 2025  Accepted February 22, 2025  
View: 180   Download: 4
Correspondence to editorial on “Integrated Molecular Characterization of Sarcomatoid Hepatocellular Carcinoma”
Rong-Qi Sun, Shao-Lai Zhou
Received February 17, 2025  Accepted February 22, 2025  
View: 205   Download: 8
Correspondence to Editorial on “Is AMA M2 a Useful Serologic Test for Screening High-Risk Patients for PBC?”
Haolong Li, Song Liu, Xu Wang, Li Wang, Tengda Xu, Yongzhe Li
Received February 16, 2025  Accepted February 21, 2025  
View: 244   Download: 19
Reply to “Metabolic dysfunction in patients following DAA-induced viral cure for HCV infection: a nonnegligible risk to liver-related health”
Tom Ryu, Young Chang, Seung Up Kim, Jae Young Jang
Received February 15, 2025  Accepted February 21, 2025  
View: 163   Download: 7
Editorial
Direct-acting antiviral attained sustained virological response improve overall survival in patients with HCV-related hepatocellular carcinoma
Yan Ling Ong, Apichat Kaewdech, Daniel Q Huang, Yu Jun Wong
Received February 14, 2025  Accepted February 21, 2025  
View: 292   Download: 21
Letter to the Editor
Classification of microvascular invasion of hepatocellular carcinoma: different standards, common goals
Wei Chen, Yihui Rong, Tianshi Ma, Weiwei Shi, Wei Chen, Hang Jiang
Received February 11, 2025  Accepted February 14, 2025  
View: 288   Download: 33
Letter to the editor on "Bariatric surgery reduces long-term mortality in patients with metabolic dysfunction-associated steatotic liver disease and cirrhosis"
Wei Wang, Yating Xie, Ailei Xu
Received February 7, 2025  Accepted February 16, 2025  
View: 244   Download: 19
Correspondence
Correspondence to “Burden of alcohol use disorder, alcohol-related liver disease, and alcohol-related liver cancer”
Pojsakorn Danpanichkul, Luis Antonio Diaz, Kanokphong Suparan, Karn Wijarnpreecha, Juan Pablo Arab
Received February 11, 2025  Accepted February 14, 2025  
View: 340   Download: 21
Response to Editorial on “Exploring Methylation Signatures for High De Novo Recurrence Risk in Hepatocellular Carcinoma”
Kwang-Woong Lee, Young-Joon Kim
Received February 11, 2025  Accepted February 14, 2025  
View: 234   Download: 13
Editorial
Metabolic dysfunction in patients following DAA-induced viral cure for HCV infection: a nonnegligible risk to liver-related health
Chen-Hua Liu, Yu-Ping Chang
Received February 9, 2025  Accepted February 14, 2025  
View: 211   Download: 23
Correspondence
The Burden of Steatotic Liver Disease before and during the COVID Pandemic Correspondence to editorial on “Revealing the importance of a multidisciplinary approach to reducing the global burden of SLD in the COVID-19 pandemic (CMH-2025-0019)”
Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed
Received February 9, 2025  Accepted February 14, 2025  
View: 226   Download: 6
Reply to Correspondence
Decreasing systemic inflammation after TIPS: Still hope for the liver Response to correspondence to an editorial on: TIPS insertion leads to sustained reversal of systemic inflammation in patients with decompensated liver cirrhosis
Georg SEMMLER, Lorenz BALCAR, Mattias MANDORFER
Received February 8, 2025  Accepted February 14, 2025  
View: 220   Download: 18
Reply to correspondence on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
Yoon-su Ha, Won Kim, Seung-Jin Kim
Received February 4, 2025  Accepted February 12, 2025  
View: 422   Download: 19
Correspondence
Addressing the Burden of Steatotic Liver Disease: The Role of Transient Elastography: Correspondence to editorial on “Vibration-controlled transient elastography in shaping the epidemiology and management of steatotic liver disease”
Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed
Received February 4, 2025  Accepted February 12, 2025  
View: 245   Download: 15
GOLM1 and Bile Acid Synthesis: Correspondence to the Editorial “Bridging the Gap: The GOLM1-OPN-ABCG5 Axis in MASH and Gallstone Disease”
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Jing Lin, Jin-Hong Chen
Received February 3, 2025  Accepted February 12, 2025  
View: 271   Download: 19
Editorial
Is AMA M2 a Useful Serologic Test for Screening High-Risk Patients for PBC?
Nae-Yun Heo
Received February 3, 2025  Accepted February 11, 2025  
View: 209   Download: 12
Risk stratification for hepatocellular carcinoma in metabolic dysfunction-associated steatotic liver disease
Ho Soo Chun, Minjong Lee
Received February 2, 2025  Accepted February 7, 2025  
View: 261   Download: 14
Tetraspan(in)-mediated immune regulation in hepatocellular carcinoma
Seo Hee Jin, Dong Joo Kim, Jung Weon Lee
Received January 31, 2025  Accepted February 7, 2025  
View: 305   Download: 51
Correspondence
TIPS insertion and systemic inflammation: Is it ever too late to lower portal pressure?
Anja Tiede, Benjamin Maasoumy
Received February 6, 2025  Accepted February 6, 2025  
View: 188   Download: 10
Editorial
Burden of alcohol use disorder, alcohol-related liver disease, and alcohol-related liver cancer
Youxin Wang, Noriko Oza, Jazleen Leo, Ashok Choudhury, Daniel Q. Huang
Received February 5, 2025  Accepted February 6, 2025  
View: 465   Download: 41
TM4SF1 - A new immune target for treatment of hepatocellular carcinoma
Chen Rui YUAN, Terence Kin Wah LEE
Received January 29, 2025  Accepted February 6, 2025  
View: 275   Download: 24
Original Article
Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target
Gu-Wei Ji, Zheng-Gang Xu, Shuo-Chen Liu, Shu-Ya Cao, Chen-Yu Jiao, Ming Lu, Biao Zhang, Yue Yang, Qing Xu, Xiao-Feng Wu, Ke Wang, Yong-Xiang Xia, Xiang-Cheng Li, Xue-Hao Wang
Received October 9, 2024  Accepted February 7, 2025  
View: 5977   Download: 166
Letter to the Editor
Letter to the editor on “Bariatric surgery reduces long-term mortality in patients with metabolic dysfunction-associated steatotic liver disease and cirrhosis”
Chi-Kuei Hsu, Po-Yu Huang, Chih-Cheng Lai
Received January 19, 2025  Accepted February 4, 2025  
View: 260   Download: 15
Snapshot
Interventions Targeting the Gut-Liver Axis: A Potential Treatment Strategy for MASLD
Pingping Jin, Xinyi Lu, Daozhen Chen, Yu Chen
Received December 2, 2024  Accepted February 4, 2025  
View: 390   Download: 63
Original Article
GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma
Hyung Seok Kim, Jung Hwan Yoon, Ji Yi Choi, Moon Gyeong Yoon, Geum Ok Baek, Minji Kang, Se Ha Jang, Won Park, Yunjin Go, Jestlin Tianthing Ng, Suk Woo Nam, Jee-Yeong Jeong, Ji Eun Han, Hyo Jung Cho, Su Bin Lim, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun
Received November 19, 2024  Accepted February 4, 2025  
View: 1553   Download: 445
Correspondence
Correspondence to Editorial on “Targeting TM4SF1 to overcome immunotherapy resistance in hepatocellular carcinoma”
Weifeng Zeng, Furong Liu, Yachong Liu, Zhanguo Zhang
Received January 22, 2025  Accepted February 1, 2025  
View: 291   Download: 18
Review
Deciphering adenosine signaling in hepatocellular carcinoma: pathways, prognostic models, and therapeutic implications
Huihai Yang, Martina Mang Leng Lei, Longfei Xie, Yinuo Shou, Terence Kin Wah Lee
Received November 26, 2024  Accepted February 2, 2025  
View: 878   Download: 92
Original Article
Direct-acting antiviral therapy for patients with HCV-related hepatocellular carcinoma: A nationwide cohort study
Shou-Wu Lee, Sheng-Shun Yang, Pei-Chien Tsai, Chung-Feng Huang, Chi-Yi Chen, Chao-Hung Hung, Chien-Hung Chen, Chi-Ming Tai, Pin-Nan Cheng, Hsing-Tao Kuo, Kuo-Chih Tseng, Lein-Ray Mo, Ching-Chu Lo, Yi-Hsiang Huang, Han-Chieh Lin, Pei-Lun Lee, Ming-Jong Bair, Te-Sheng Chang, Chun-Yen Lin, Szu-Jen Wang, Tsai-Yuan Hsieh, Tzeng-Hue Yang, Cheng-Yuan Peng, Chi-Chieh Yang, Lee-Won Chong, Chien-Wei Huang, Chih-Wen Lin, Cheng-Hsin Chu, Ming-Chang Tsai, Jia-Horng Kao, Chun-Jen Liu, Wan-Long Chuang, Teng-Yu Lee, Ming- Lung Yu, on behalf of TACR investigators
Received November 10, 2024  Accepted January 16, 2025  
View: 959   Download: 74
FIB-4plus Score: A novel machine learning-based tool for screening high-risk varices in compensated cirrhosis (CHESS2004): An international multicenter study
Bingtian Dong, Ruiling He, Shenghong Ju, Yuping Chen, Ivica Grgurevic, Jianzhong Ma, Ying Guo, Huizhen Fan, Qiang Yan, Chuan Liu, Huixiong Xu, Anita Madir, Kristian Podrug, Jia Wang, Linxue Qian, Zhengzi Geng, Shanghao Liu, Tao Ren, Guo Zhang, Kun Wang, Meiqin Su, Fei Chen, Sumei Ma, Liting Zhang, Zhaowei Tong, Yonghe Zhou, Xin Li, Fanbin He, Hui Huan, Wenjuan Wang, Yunxiao Liang, Juan Tang, Fang Ai, Tingyu Wang, Liyun Zheng, Zhongwei Zhao, Jiansong Ji, Wei Liu, Jiaojiao Xu, Bo Liu, Xuemei Wang, Yao Zhang, Qiong Yan, Hui Liu, Xiaomei Chen, Shuhua Zhang, Yihua Wang, Yang Liu, Li Yin, Yanni Liu, Yanqing Huang, Li Bian, Ping An, Xin Zhang, Shaoting Zhang, Jinhua Shao, Xiangman Zhang, Wei Rao, Chaoxue Zhang, Christoph Frank Dietrich, Won Kim, Xiaolong Qi
Received October 10, 2024  Accepted February 3, 2025  
View: 1160   Download: 112
GDH1-dependent α-ketoglutarate promotes HBV transcription by modulating histone methylations on the cccDNA minichromosome
Sheng-Tao Cheng, Wei-Xian Chen, Hai-Jun Deng, Xin He, Hui Zhang, Ming Tan, Hai-Bo Yu, Zhen-Zhen Zhang, Ji-Hua Ren, Min-Li Yang, Da-Peng Zhang, Zhi-Hong Li, Juan Chen
Received August 21, 2024  Accepted January 28, 2025  
View: 793   Download: 157
Baveno VI-SSM stratifies the risk of portal hypertension-related events in patients with HBV-related cirrhosis
Haiyu Wang, Weihao Liang, Ling Zhou, Jiankang Song, Biao Wen, Qiaoping Wu, Yuanjian Zhang, Xiaofeng Zhang, Haoran Ke, Yujun Tang, Fuyuan Zhou, Youfu Zhu, Weiqun Wen, Zhihua Liu, Yali Ji, Qintao Lai, Qinjun He, Wenfan Luo, Tingting Qi, Miaoxia Liu, Xiaoqin Lan, Yongpeng Chen, Ranran Xi, Junting Wan, Lin Dai, Yuan Li, Jinjun Chen
Received July 29, 2024  Accepted January 29, 2025  
View: 560   Download: 67
Reply to Correspondence
Reply to correspondence to editorial on “Bariatric Surgery Reduces Long-Term Mortality in Patients with MASLD and Cirrhosis”
Jing Zeng, Jian-Gao Fan
Received January 19, 2025  Accepted January 24, 2025  
View: 306   Download: 13
Correspondence
Correspondence to editorial on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Jing Lin, Jin-Hong Chen
Received January 21, 2025  Accepted January 23, 2025  
View: 258   Download: 25
Editorial
Intrapatient variability of tacrolimus trough level may be not the cause, but an indirect parameter of comorbidities
Jongman Kim
Received January 20, 2025  Accepted January 23, 2025  
View: 243   Download: 25
Genetic Insights into Sarcomatoid Hepatocellular Carcinoma: Critical Role of ARID2 in Pathogenesis and Immune Feature
Naoshi Nishida
Received January 19, 2025  Accepted January 23, 2025  
View: 257   Download: 17
Review
Unveiling the Intratumor Microbiome in Liver Cancer: Current Insights and Prospective Applications
Xindi Ke, Shangze Jiang, Qiaoxin Wei, Minghao Sun, Hang Sun, Mingchang Pang, Mei Liu, Lejia Sun, Huayu Yang, Yilei Mao
Received November 19, 2024  Accepted January 20, 2025  
View: 745   Download: 91
Original Article
Modulation of PRL-1 within placental MSCs instigates the transition between EMT and MET subsequent to hepatic fibrosis
Jae Yeon Kim, Hyeri Park, Soo Young Park, Se Ho Kim, Ja Yun Lim, Ki Seog Lee, Si Hyun Bae, Gi Jin Kim
Received September 12, 2024  Accepted January 20, 2025  
View: 3976   Download: 730
Letter to the Editor
What is new in the 2024 Chinese guidelines for fatty liver disease?
Rui-Xu Yang, Vincent Wai-Sun Wong, Jian-Gao Fan
Received December 27, 2024  Accepted January 18, 2025  
View: 335   Download: 31
Original Article
Switching to Besifovir in Patients with Chronic Hepatitis B Receiving Tenofovir Disoproxil Fumarate: A Randomized Trial
Hyung Joon Yim, Yeon Seok Seo, Ji Hoon Kim, Won Kim, Young Kul Jung, Jae Young Jang, Sae Hwan Lee, Yun Soo Kim, Chang Wook Kim, Hyoung Su Kim, Jae-Jun Shim, Eun-Young Cho, In Hee Kim, Byung Seok Lee, Jeong-Hoon Lee, Byung Seok Kim, Jeong Won Jang, Hyun Woong Lee, Jung Hyun Kwon, Moon Young Kim, Do Seon Song, Jung Gil Park, Yoon Seok Lee, Eileen L. Yoon, Han Ah Lee, Seong Hee Kang, Jin Mo Yang
Received September 19, 2024  Accepted January 16, 2025  
View: 1064   Download: 56
Editorial
Unraveling the role of GOLM1-OPN-ABCG5 axis in MASH: Editorial on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
Yoon-su Ha, Won Kim, Seung-Jin Kim
Received January 10, 2025  Accepted January 13, 2025  
View: 584   Download: 29
Reply to Correspondence
Reply to correspondence on “Circulating cell-free mitochondrial DNA for diagnosing hepatocellular carcinoma and assessing prognosis”
Hyuk Soo Eun
Received January 10, 2025  Accepted January 12, 2025  
View: 381   Download: 13
Editorial
Targeting TM4SF1 to overcome immunotherapy resistance in hepatocellular carcinoma
Valerie Chew
Received January 9, 2025  Accepted January 12, 2025  
View: 413   Download: 34
Original Article
Exploring Methylation Signatures for High De Novo Recurrence Risk in Hepatocellular carcinoma
Da-Won Kim, Jin Hyun Park, Suk Kyun Hong, Min-Hyeok Jung, Ji-One Pyeon, Jin-Young Lee, Kyung-Suk Suh, Nam-Joon Yi, YoungRok Choi, Kwang-Woong Lee, Young-Joon Kim
Received October 11, 2024  Accepted January 7, 2025  
View: 375   Download: 40
Correspondence
Correspondence to Editorial on “Bariatric Surgery Reduces Long-Term Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Cirrhosis”
Nicholas A. Rouillard, Linda Henry, Mindie H. Nguyen
Received January 1, 2025  Accepted January 4, 2025  
View: 350   Download: 16
Letter to the Editor
Tacrolimus Levels and Variability in CKD and ESRD Risk Post-Liver Transplant
Rui Shi, Minghua Wang
Received December 21, 2024  Accepted January 6, 2025  
View: 357   Download: 21
Original Article
Adverse impact of metabolic dysfunction on fibrosis regression following direct-acting antiviral therapy: A multicenter study for chronic hepatitis C
Tom Ryu, Young Chang, Soung Won Jeong, Jeong-Ju Yoo, Sae Hwan Lee, Sang Gyune Kim, Young Seok Kim, Hong Soo Kim, Seung Up Kim, Jae Young Jang
Received October 12, 2024  Accepted January 5, 2025  
View: 512   Download: 61  Crossref: 1
Global Epidemiology of Alcohol-Related Liver Disease, Liver Cancer, and Alcohol Use Disorder, 2000–2021
Pojsakorn Danpanichkul, Luis Antonio Díaz, Kanokphong Suparan, Primrose Tothanarungroj, Supapitch Sirimangklanurak, Thanida Auttapracha, Hanna L. Blaney, Banthoon Sukphutanan, Yanfang Pang, Siwanart Kongarin, Francisco Idalsoaga, Eduardo Fuentes-López, Lorenzo Leggio, Mazen Noureddin, Trenton M. White, Alexandre Louvet, Philippe Mathurin, Rohit Loomba, Patrick S. Kamath, Jürgen Rehm, Jeffrey V. Lazarus, Karn Wijarnpreecha, Juan Pablo Arab
Received September 26, 2024  Accepted January 3, 2025  
View: 2079   Download: 197  Crossref: 3
Correspondence
Correspondence on Editorial regarding “Usefulness of circulating cell-free mitochondrial DNA on hepatocellular carcinoma diagnosis and prognosis assessment”
Yang Liu, Fan Peng, Siyuan Wang, Jinliang Xing
Received December 30, 2024  Accepted January 1, 2025  
View: 295   Download: 20
Editorial
Treating systemic inflammation by transjugular intrahepatic portosystemic shunt
Georg Semmler, Lorenz Balcar, Mattias Mandorfer
Received January 29, 2024  Accepted January 1, 2025  
View: 345   Download: 34
Correspondence
Reply to “MAFLD or MASLD: Which Better Represents the Prognosis of the Steatotic Liver Population”
Seogsong Jeong, Won Kim, Sang Min Park
Received December 26, 2024  Accepted January 2, 2025  
View: 560   Download: 16
Reply to “Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma”
Seogsong Jeong, Won Kim, Sang Min Park
Received December 23, 2024  Accepted January 2, 2025  
View: 544   Download: 14
Original Article
High SAFE scores predict hepatocellular carcinoma in viral and non-viral hepatitis and metabolic dysfunction associated steatotic liver disease
Tung-Hung Su, Sheng-Shun Yang, Mei-Hsuan Lee, Wei-Yu Kao, Shang-Chin Huang, Fen-Fang Chen, Francis SK Poon, Lung-Wen Tsai, Yi-Ting Chen, Che Lin, Weichung Wang, W Ray Kim, Jia-Horng Kao
Received September 21, 2024  Accepted January 1, 2025  
View: 955   Download: 100
Male preference for TERT alterations and HBV integration in young-age HBV-related HCC: implications for sex disparity
Jin Seoub Kim, Hye Seon Kim, Kwon Yong Tak, Ji Won Han, Heechul Nam, Pil Soo Sung, Sung Won Lee, Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang
Received July 10, 2024  Accepted December 30, 2024  
View: 778   Download: 75
Correspondence
Age serves as the silent architect of FIB-4's precision in unveiling advanced hepatic fibrosis in MASLD with T2DM
Ji Won Han, Dae Won Jun
Received December 22, 2024  Accepted December 26, 2024  
View: 348   Download: 21
Letter to the Editor
Current Burden of MASLD, MetALD, and Hepatic Fibrosis among US Adults with Prediabetes and Diabetes, 2017-2023
Donghee Kim, Rohit Loomba, Aijaz Ahmed
Received December 20, 2024  Accepted December 29, 2024  
View: 942   Download: 116
Original Article
Targeting TM4SF1 promotes tumor senescence enhancing CD8+ T cell cytotoxic function in hepatocellular carcinoma
Weifeng Zeng, Furong Liu, Yachong Liu, Ze Zhang, Haofan Hu, Shangwu Ning, Hongwei Zhang, Xiaoping Chen, Zhibin Liao, Zhanguo Zhang
Received October 28, 2024  Accepted December 26, 2024  
View: 1284   Download: 213
Prediction of primary biliary cholangitis among health check-up population with anti-mitochondrial M2 antibody positive
Haolong Li, Song Liu, Xu Wang, Xinxin Feng, Siyu Wang, Yanli Zhang, Fengchun Zhang, Li Wang, Tengda Xu, Yongzhe Li
Received June 3, 2024  Accepted December 25, 2024  
View: 629   Download: 88  Crossref: 1
Editorial
Circulating cell-free mitochondrial DNA for diagnosing hepatocellular carcinoma and assessing prognosis
Hyuk soo Eun
Received December 15, 2024  Accepted December 20, 2024  
View: 409   Download: 31
Vibration-Controlled Transient Elastography in Shaping the Epidemiology and Management of Steatotic Liver Disease
Xiao-Dong Zhou, Terry Cheuk-Fung Yip, Daniel Q Huang, Mark Dhinesh Muthiah, Mazen Noureddin, Ming-Hua Zheng
Received December 14, 2024  Accepted December 20, 2024  
View: 886   Download: 38  Crossref: 1
Letter to the Editor
MAFLD or MASLD: Which Better Represents the Prognosis of the Steatotic Liver Population
Ying Wang, Shengfeng Wang, Xiude Fan, Jiajun Zhao, Yongfeng Song
Received November 8, 2024  Accepted December 24, 2024  
View: 702   Download: 61  Crossref: 1
Original Article
Longitudinal profile of plasma pregenomic RNA in patients with chronic hepatitis B infection on long-term nucleoside analogues and its interaction with clinical parameters
Lung-Yi Mak, Mark Anderson, Michael Stec, Matthew Shing-Hin Chung, Danny Ka-Ho Wong, Rex Wan-Hin Hui, Wai-Kay Seto, Gavin Cloherty, Man-Fung Yuen
Received August 27, 2024  Accepted December 21, 2024  
View: 665   Download: 77
Correspondence
Expanding Treatment Eligibility for Chronic Hepatitis B: Balancing Benefits, Limitations, and Healthcare Access
Yao-Chun Hsu, Chi-Yi Chen, Jaw-Town Lin
Received December 16, 2024  Accepted December 20, 2024  
View: 336   Download: 13
Original Article
MARC1 downregulation reduces hepatocyte lipid content by increasing beta-oxidation
Ester Ciociola, Tanmoy Dutta, Kavitha Sasidharan, Lohitesh Kovooru, Francesca R. Noto, Grazia Pennisi, Salvatore Petta, Angela Mirarchi, Samantha Maurotti, Bernardette Scopacasa, Luca Tirinato, Patrizio Candeloro, Marcus Henricsson, Daniel Lindén, Oveis Jamialahmadi, Arturo Pujia, Rosellina M. Mancina, Stefano Romeo
Received August 13, 2024  Accepted December 20, 2024  
View: 1460   Download: 267  Crossref: 1
Editorial
A leap in the dark: Bariatric surgery for treatment of metabolic dysfunction-associated steatotic liver disease related cirrhosis
Jing Zeng, Jian-Gao Fan
Received December 5, 2024  Accepted December 14, 2024  
View: 478   Download: 29
Letter to the Editor
Comment on: Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma
Hai Xu, Yong Zhou, Huikun Wu
Received December 2, 2024  Accepted December 16, 2024  
View: 490   Download: 13
Global Inequality in the Burden of Hepatitis B From 1990 to 2021: Findings From the Global Burden of Disease Study 2021
Chunlong Liu, Jiangtao Yu
Received December 1, 2024  Accepted December 16, 2024  
View: 582   Download: 74
Original Article
Plasma lipidomics and fungal peptide-based community analysis identifies distinct signatures of early mortality in acute liver failure
Neha Sharma, Sushmita Pandey, Gaurav Tripathi, Manisha Yadav, Nupur Sharma, Babu Mathew, Abhishak Gupta, Vasundhra Bindal, Sadam H. Bhat, Yash magar, Rimsha Saif, Sanju Yadav, Amritpal Kaur, Rakhi Maiwall, Shvetank Sharma, Shiv Kumar Sarin, Jaswinder Singh Maras
Received July 12, 2024  Accepted December 10, 2024  
View: 936   Download: 91
Review Article
Gut microbiota-mediated gut-liver axis: a breakthrough point for understanding and treating liver cancer
Chenyang Li, Chujun Cai, Chendong Wang, Xiaoping Chen, Bixiang Zhang, Zhao Huang
Received September 30, 2024  Accepted December 6, 2024  
View: 1188   Download: 156
Original Article
Integrated Molecular Characterization of Sarcomatoid Hepatocellular Carcinoma
Rong-Qi Sun, Yu-Hang Ye, Ye Xu, Bo Wang, Si-Yuan Pan, Ning Li, Long Chen, Jing-Yue Pan, Zhi-Qiang Hu, Jia Fan, Zheng-Jun Zhou, Jian Zhou, Cheng-Li Song, Shao-Lai Zhou
Received August 21, 2024  Accepted December 6, 2024  
View: 1041   Download: 115
GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Xiao-Chen Ma, Chen-He Yi, Bao-Rui Tao, Bo Zhang, Yue Ma, Guo Zhang, Rui Zhang, Yan Geng, Jing Lin, Jin-Hong Chen
Received August 12, 2024  Accepted December 5, 2024  
View: 1192   Download: 193  Crossref: 1
Editorial
Reconsidering Treatment Indications for Chronic Hepatitis B: Insights from the TORCH-B Roll-Over Study
Chih-Wen Wang, Ming-Lung Yu
Received November 28, 2024  Accepted November 30, 2024  
View: 450   Download: 15
Letter to the Editor
Treatment response to nucleos(t)ide analogs in chronic hepatitis B with mildly elevated alanine aminotransferase
Jian Wang, Fei Cao, Chuanwu Zhu, Chao Wu, Rui Huang
Received October 29, 2024  Accepted November 29, 2024  
View: 404   Download: 17
Original Article
Cost-effectiveness and return on investment of hepatitis C virus elimination in China: A modelling study
Meiyu Wu, Jing Ma, Xuehong Wang, Sini Li, Chongqing Tan, Ouyang Xie, Andong Li, Aaron G Lim, Xiaomin Wan
Received August 13, 2024  Accepted December 2, 2024  
View: 886   Download: 122
Correspondence
HCV Self-Testing: Bridging Screening Gaps and Ensuring Cost-Effectiveness for Both High-Risk and Universal Populations
Gyeongseon Shin, Beom Kyung Kim, SeungJin Bae, Hankil Lee, Sang Hoon Ahn
Received November 23, 2024  Accepted November 26, 2024  
View: 404   Download: 22
Original Article
Current Burden of Steatotic Liver Disease and Fibrosis among Adults in the United States, 2017-2023
Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed
Received November 3, 2024  Accepted November 26, 2024  
View: 2023   Download: 361  Crossref: 5
Editorial
Universal self-testing as a cost-effective weapon to eliminate hepatitis C virus in the Republic of Korea
Eun Sun Jang
Received November 5, 2024  Accepted November 7, 2024  
View: 418   Download: 9
Correspondence
Correspondence to editorials on “Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial”
Woo Hyun Paik, Do Hyun Park
Received November 4, 2024  Accepted November 7, 2024  
View: 392   Download: 25
Review
Stem cell exosomes: new hope and future potential for relieving liver fibrosis
Lihua Li, Yongjie Liu, Kunpeng Wang, Jinggang Mo, Zhiyong Weng, Hao Jiang, Chong Jin
Received September 29, 2024  Accepted November 5, 2024  
View: 1782   Download: 261
Editorial
Stabilizing Hepatic Fatty Acid Oxidation: USP29 Secures Acyl-CoA Synthesis through ACSL5
Myeung Gi Choi, Na Young Lee, Ja Hyun Koo
Received October 31, 2024  Accepted November 1, 2024  
View: 594   Download: 51
A novel clinical trial for primary sclerosing cholangitis from Asia: all regional endeavors should improve global management of PSC
Atsumasa Komori
Received October 25, 2024  Accepted November 1, 2024  
View: 437   Download: 27
Correspondence
Correspondence on Letter Regarding “Contemporary Awareness of Viral Hepatitis between 2012 and 2022 among Korean Adults”
Chang Hun Lee, In Hee Kim, Sook-Hyang Jeong
Received October 25, 2024  Accepted November 1, 2024  
View: 474   Download: 9
Editorial
Challenges and Innovations in PSC Clinical Trials: Evaluating HK-660S and the Path Forward
Nilanga Nishad
Received October 24, 2024  Accepted October 31, 2024  
View: 380   Download: 23
Momentum Towards Simplifying and Expanding Treatment for Chronic Hepatitis B: The Body of Evidence Continues to Grow
Robert J. Wong
Received October 22, 2024  Accepted October 28, 2024  
View: 358   Download: 15
Letter to the Editor
Prevalence of steatotic liver disease and associated fibrosis in the general population: an epidemiological survey
Lin Guan, Xinhe Zhang, Shanghao Liu, Xiaolong Qi, Yiling Li
Received October 17, 2024  Accepted October 28, 2024  
View: 623   Download: 59
Snapshot
MODULATION OF LYMPHATIC VESSELS IN MANAGEMENT OF LIVER DISEASE AND COMPLICATIONS
Aarti Sharma, Pinky Juneja, Shiv K Sarin, Savneet Kaur
Received September 12, 2024  Accepted October 16, 2024  
View: 494   Download: 43
Correspondence
Reply to: “From invasive to intuitive: the emerging role of non-invasive models in hepatic decompensation”
Chuan Liu, Ling Yang, Hong You, Gao-Jun Teng, Xiaolong Qi
Received August 27, 2024  Accepted August 29, 2024  
View: 658   Download: 30
Editorial
From Invasive to Intuitive: The Emerging Role of Non-Invasive Models in Hepatic Decompensation
Akhil Deshmukh, Rakhi Maiwall
Received August 13, 2024  Accepted August 13, 2024  
View: 1500   Download: 18

Clinical and
Molecular
Hepatology

Print ISSN: 2287-2728
Online ISSN: 2287-285X

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